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Charlottes Web Holdings Inc (QX)

Charlottes Web Holdings Inc (QX) (CWBHF)

0.20
0.0035
(1.78%)
Closed March 29 04:00PM

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CWBHF Discussion

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MaxwellE MaxwellE 1 day ago
$.19 is still a little to high for this POS...M
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oilfieldmafia oilfieldmafia 2 days ago
Cheap shares huh....
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2TimeTrader 2TimeTrader 4 days ago
FDA says medical Marijuana has legitimate Medicinal Purpose... 4 Days ago... https://www.abcactionnews.com/news/national/fda-says-marijuana-has-a-legitimate-medicinal-purpose
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2TimeTrader 2TimeTrader 1 week ago
Yea this will.get u cheap shares... Told u.. CBD-Focused Charlotte's Web Narrows Net Loss 75% YoY In Q4, Reports Drop In Revenue https://www.benzinga.com/markets/cannabis/24/03/37871894/cbd-focused-charlottes-web-narrows-net-loss-75-yoy-in-q4-reports-drop-in-revenue
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2TimeTrader 2TimeTrader 3 weeks ago
If Earnings numbers are bad on the 21st this is gonna dip.. Have cash ready to seize the opportunity.... Cheap shares
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GE_Jim GE_Jim 4 weeks ago
FYI- https://www.marijuanamoment.net/fda-official-says-agency-is-actively-exploring-cbd-regulations-as-it-continues-to-monitor-kratom/
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2TimeTrader 2TimeTrader 1 month ago
Mid summer this should be scraping under 0.10 and shares will be scooped up in blocks... An when big news comes those with bottom positions gonna clean up....
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GE_Jim GE_Jim 1 month ago
Hey Darth, just trying to catch up some. Back to 1 you say, no reason to respond to this one, save for a more important subject.
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DarthYoda DarthYoda 1 month ago
The "Autism" trend chart is even more shocking than the earlier chart for ASD, "Autism Spectrum Disorder"...
Does anyone have any politically correct explanations for this chart?...
"Autism"
https://trends.google.com/trends/explore?date=all&geo=US&q=%2Fg%2F121kwpxw&hl=en-US
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Wolf-man jack Wolf-man jack 1 month ago
WQLF SAYS: Great News for CV Sciences stock YQU Understand. Have Mercy Ahooooooo

The MLB sponsorship was a Biggly mistake and is going to continue burning cash to the point that the Pps will continue to plunder. BAT should just make an offer to buyout the itsy itsy bitsy spider web company. In my opinion, It seems that there is an intentional manipulation of the company stock in order to lower its market cap for a possible BAT friendly takeover was their plan from the start. BAT would be foolish to pump more monies into this losing game company. Why not just take over the company and merge the other company. That would allow BAT to bring back one of the seven hostile dwarfs. Glad to have you back. My good riddance remark was the key for your return we do Understand YQU Understand. Lollipops 🍭 Have Mercy WQLF Ahooooooo

WOLFMAN JACK SAID;


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DarthYoda DarthYoda 1 month ago
That ASD trend chart shocked me. It should be on the news.
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DarthYoda DarthYoda 1 month ago
OMG...ASD...https://trends.google.com/trends/explore?date=all&geo=US&q=%2Fm%2F02p3f5&hl=en-US
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DarthYoda DarthYoda 1 month ago
"Could an NLRP3 inhibitor be the one drug to conquer common diseases?":
February 17, 2020
https://cen.acs.org/pharmaceuticals/drug-discovery/Could-an-NLRP3-inhibitor-be-the-one-drug-to-conquer-common-diseases/98/i7
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DarthYoda DarthYoda 1 month ago
CBD's range of powers should make more sense now...
"Pharma Looks to Inflammasome Inhibitors as All-Around Therapies":
Apr 1, 2021
Many major biopharmaceutical companies are developing or acquiring drugs that target the NLRP3 inflammasome, a large intracellular complex that researchers say can spark inflammation and stoke diseases of lifestyle and aging.


https://www.the-scientist.com/pharma-looks-to-inflammasome-inhibitors-as-all-around-therapies-68582
"...finding drugs to selectively stop NLRP3 will be difficult."
https://cen.acs.org/pharmaceuticals/drug-discovery/Could-an-NLRP3-inhibitor-be-the-one-drug-to-conquer-common-diseases/98/i7
"...we emphasize the capacity of cannabidiol to suppress inflammation by blocking the NLRP3 signaling pathway..."
https://link.springer.com/article/10.1007/s00011-023-01831-y
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Fangster Fangster 1 month ago
CW still advertising on Fox News tonight. Been seeing the commercials in the mornings but first time in prime time.

I like it!!!
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DarthYoda DarthYoda 1 month ago
Hmmm...Pericarditis...https://trends.google.com/trends/explore?date=all&geo=US&q=%2Fm%2F032snl&hl=en-US
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DarthYoda DarthYoda 1 month ago
Recreate+MLB+PLL website looking good...
https://recreateyou.com/mlb
https://recreateyou.com/pll
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DarthYoda DarthYoda 1 month ago
"Farmers, businesses push back on Florida Republicans' efforts to restrict THC products"
Feb 16, 2024
https://www.orlandoweekly.com/cannabis/farmers-businesses-push-back-on-florida-republicans-efforts-to-restrict-thc-products-36201768
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DarthYoda DarthYoda 1 month ago
Same goes for ASD..."Multiple inflammasome complexes are activated in autistic spectrum disorders":
2016 Mar 12
Abstract
Background: Inflammasomes are multimeric protein platforms involved in the regulation of inflammatory responses whose activity results in the production of proinflammatory cytokines. Because neuroinflammation is observed in autistic spectrum disorders (ASD), a neurologic condition of childhood resulting in a complex behavioural impairment, we analyzed the inflammasomes activity in ASD. Additionally we verified whether alterations of the gastrointestinal (GI) barriers might play a role in inflammasomes activation.

Methods: The activity of the inflammasomes, the concentration of the inflammasomes-derived proinflammatory cytokines interleukin (IL)-1ß and IL-18, and serum parameters of GI damage were analyzed in 25 ASD children, 23 healthy siblings (HS) and 30 unrelated age-matched healthy controls (HC).

Results: A significant upregulation of the AIM2 and the NLRP3 inflammasomes and an increased production of IL-1ß and IL-18 that was associated with a consistent reduction of IL-33, an anti inflammation cytokine were observed in ASD alone. Notably, in a possible immune-mediated attempt to dampen inflammation, IL-37, a suppressor of innate inflammatory responses, was significantly augmented in these same children. Finally, intestinal fatty acid binding protein (IFABP), an index of altered GI permeability, was significantly increased in serum of ASD and HS.

Conclusions: These results show that the inflammasomes are activated in ASD and shed light on the molecular mechanisms responsible for ASD-associated neuroinflammation. The observation that GI alterations could be present as well in ASD offers a possible link between such alterations and neuroinflammation. Therapeutic strategies targeting inflammasome activation could be useful in ASD.
https://pubmed.ncbi.nlm.nih.gov/26979869/
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DarthYoda DarthYoda 1 month ago
"Inflammasomes"...Looks like we're on to something here...CBD/Hemp extract has shown promise for all of these conditions as well...
"...Inflammasome Activation Is Pathogenic in Multiple Neurological Diseases":
Feb. 14, 2024
This article provides increasing evidence that activation of several types of inflammasomes and extracellular ASC specks contribute to the development and progression of multiple neurological diseases including Alzheimer’s disease (AD), Parkinson’s disease (PD), multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), epilepsy, traumatic brain injury (TBI), and stroke.

Many neurological conditions involve an underlying chronic inflammasome-mediated inflammatory process that worsens the trajectory of these conditions.
Beyond NLRP3, evidence suggests that other inflammasomes, including but not restricted to NLRP1, NLRC4, and AIM2, and their downstream effectors contribute to neuropathology in AD, PD, ALS, MS, stroke, epilepsy, and TBI.
https://markets.businessinsider.com/news/stocks/zyversa-therapeutics-highlights-review-article-substantiating-that-inflammasome-activation-is-pathogenic-in-multiple-neurological-diseases-1033066259
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DarthYoda DarthYoda 1 month ago
Re: Social benefit projects...I was happy with what these guys were doing with Realm of Caring and thought they would do more together. Maybe the FDA would pick on them for it now. I don't know, but I do think CW should do all, most, or at least some of their social benefit work through RoC. It made more sense IMO.
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DarthYoda DarthYoda 1 month ago
Well, whaddya know. FDA grants orphan drug status for a CBD formulation to protect from a very popular "vaccine" side effect, based on the NLRP3 inflammasome I posted about a couple weeks ago..."Cannabidiol Formulation Granted Orphan Drug Designation for Pericarditis":
February 15, 2024
The Food and Drug Administration (FDA) has granted Orphan Drug designation to CardiolRx™ (cannabidiol oral solution) for the treatment of recurrent pericarditis. The NLRP3 inflammasome is known to play a key role in the inflammation and fibrosis associated with pericarditis.
https://www.empr.com/home/news/drugs-in-the-pipeline/cannabidiol-formulation-granted-orphan-drug-designation-for-pericarditis/
"The NLRP3 inflammasome: a vital player in inflammation and mediating the anti-inflammatory effect of CBD":
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=173751754
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Wolf-man jack Wolf-man jack 1 month ago
🐺 WISE WOLF SAYS 🐺

Get ready to push the button for the 10 cents coming soon 🔜 Possibly next week…. Have Mercy WQLF Ahooooooo
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Wolf-man jack Wolf-man jack 1 month ago
AP 17 SAID;

https://investorshub.advfn.com/boards/read_msg.aspx?message_id=171562405

https://investorshub.advfn.com/boards/read_msg.aspx?message_id=173860431
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Wolf-man jack Wolf-man jack 1 month ago
🐺 WOLF SAYS; It appears that there is now a “Hail Mary” attempt to pump this stock back up. Will this succeed? We shall see real soon You Understand. Have Mercy WQLF Ahooooooo

Dr. Joong J Fang Said; It appears that it is Getting closer to a buyout by the CANCER STICK company. They must be waiting for the price of the stock to fall to the single digits. The environment is ripe for this LOW CAP Stock to be easily taken over. IMO
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DarthYoda DarthYoda 1 month ago
"Why to consider botanical drug INDs?":
Dietary supplements:
-Cannot make medical claims: dietary supplements are restricted from making medical claims, limiting their market positioning.
-Low market barrier and high competition
-High product development cost leading to low-profit margin
What a botanical drug IND provides:
-A botanical drug IND allows you to make distinct medical claims, creating a market barrier
-Botanical drugs are not required to show specific active ingredients.
-Botanical drugs can be developed from a single plant or a blend of multiple plants, providing flexibility in product development.
-No need to describe the mechanism of action
-The success rate is significantly higher when developing known safe and effective botanical products compared to synthesizing or purifying new chemical molecules.
-The concept of botanical drugs primarily exists within the FDA regulatory framework and is specific to the process of regulatory filing and approval. Once botanical products receive approval as prescription drugs and enter the market, there is no perceived difference from chemical drugs.
https://www.botanicaldrug.org/service
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DarthYoda DarthYoda 1 month ago
"Botanical Drug Development Guidance for Industry":
https://www.fda.gov/media/93113/download
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DarthYoda DarthYoda 1 month ago
https://www.fda.gov/about-fda/center-drug-evaluation-and-research-cder/frequently-asked-questions-botanical-drug-product-development
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DarthYoda DarthYoda 1 month ago
Fwiw, I was happy to see the CEO of Ben and Jerry's in the picture at all as I sent the company an email suggesting they work with Ben and Jerry's years ago. I meant something more like a business venture though and not just another board member as I think this company has had way too many execs and board members passing through already. They need permanent long term people who are dedicated to the bigger long term goals. Hopefully, something bigger can come out of them working together. I saw he took no shares when he joined the Board, which is different than usual...
https://www.otcmarkets.com/filing/html?id=17247304&guid=5Qd-kKhdNG6Vvhh
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DarthYoda DarthYoda 1 month ago
I am aware of the very real effect of full spectrum hemp extract on Autism and I think that should be one of the best and most widespread uses for it. I am still waiting for an autistic spectrum relative's federal legal situation(drug tests) to finish up after many years so they can try it for the first time. I think it could be a life changer for them. My pessimism here comes only from the business side, not the science side at all.
I also am not a fan of corporate America's version of "social equity". "Get woke, go broke" is a well known saying now for a reason. I'd like to see CW drop the B corp designation, donate to an appropriate charity when it makes sense, and stop giving away money, products, and company IP based on sexual preference and skin color. Corporate wokeness is just racism and bigotry and was supposed to be illegal in America. I grew up in a genuinely multicutural way, in one of the most multicultural neighborhoods in America, with friends and girlfriends of all races, so the fake woke shit is just nails on a chalk board to me. Gay people are not victims who deserve free money just because they are gay and it's not ok to give away shareholder IP to farmers just because they are Black farmers and not White or Asian farmers.
I honestly can't believe I've found my self explaining this stuff to adults who run million or billion dollar corporations in 2024, but here we are, that's our country now, a confused cult. I never expected Big Tobacco to be involved here, and am surprised I stuck around after they showed up. However, if they can stick to CW's original mission, I am all for their redemption. This company's social goals were originally supposed to be about disabled children and adults who lacked access to the plant. That is a mission I can respect. Those people really do need the products and support. I wont be lead astray like the kids today though into cheering for a social philosophy that I know is the exact opposite direction of where the country was headed 15-25 years ago, when we were much more on the right track. I want to see the original mission succeed and will criticize deviation from that, especially when it is morally bankrupt and detrimental to shareholders.
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Fangster Fangster 1 month ago
Good stuff! For those that understand partnership structuring, they should like this disclosure. Sure, the preferred is first in line but a ton of potential upside to the common interests otherwise.

I read the technical stuff you post albeit the science is above me but I get what I need from it. Lots white papers turning up on the medicinal side of CBD. I’m not suggesting defloia will be the next best thing but pharma grade botanicals are going to be an explosive sector. Question is when it starts.
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Fangster Fangster 1 month ago
I get the pessimism on the stock. However, AJNA -001 is going to put eyes on CW this year and maybe sooner than later.
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DarthYoda DarthYoda 1 month ago
???...Select symbol
Canada
CWEB:TORTSX
United States
CWBHF:QXEOTCQX International
Germany
6CW:FRAFrankfurt Stock Exchange
6CW:DEUGerman Composite
6CW:DUSDusseldorf Stock Exchange
6CW:BERBerlin Stock Exchange
6CW:MUNMunich Stock Exchange
6CW:STUStuttgart Stock Exchange
https://markets.ft.com/data/equities/tearsheet/summary?s=6CW:BER
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2TimeTrader 2TimeTrader 1 month ago
I'm gonna wait till mid July August if this goes under 0.10 I'm gonna load up.. News looming of DEA rescheduling, and FDA news of regulations for CBD and Hemp... An Banking still be addressed... All excellent catalysts and After November Presidential elections Cannabis sector really heats up... Patience will pay.. Good luck everyone...
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DarthYoda DarthYoda 1 month ago
https://defloria.bio/ On April 6, 2023, the Company announced the formation of DeFloria LLC, a Delaware limited liability company (“DeFloria”) with AJNA BioSciences PBC (“AJNA”), and a subsidiary of British American Tobacco PLC (LSE: BATS and NYSE: BTI) (“BAT”). BAT holds a 100% equity interest in the preferred units of DeFloria and the Company and AJNA each hold 50% of the joint venture’s voting common units. The Company’s contribution to the joint venture was a license permitting the use of certain proprietary hemp intellectual properties, including clinical and consumer data.

Effective February 12, 2024, the Company and DeFloria entered into a Master Services Agreement (“Services Agreement”) pursuant to which the Company will be compensated for the provision of certain services to DeFloria. The services include assistance with Standard Operating Procedures (SOPs), product testing, stability testing, lab liaison, sampling of product, sample submission, data review, Out of Specification (OOS) evaluation, BMCS, document creation, documentation transition project, BR review, spec/RF creation, clinical trials advisory, OOS and risk mitigation testing.
https://www.otcmarkets.com/filing/html?id=17276969&guid=8dd-keHwt05eJth
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DarthYoda DarthYoda 1 month ago
New 8-K...not sure why the big drop...
https://www.otcmarkets.com/filing/html?id=17276969&guid=8dd-keHwt05eJth
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DarthYoda DarthYoda 1 month ago
Couldn't resist...
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=173852245
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=173852354
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Wolf-man jack Wolf-man jack 1 month ago
WOLF SAYS; In Reality you only had two choice You Understand. You could have had a V-8 or CVSI Undervalued CVSI stock. In the past the itsy itsy bitsy spider 🕷️ web company had an eight and ten fold advantage in Pps over CVSI. It has now been cut to 2.5 times the price per share of CWBHF over CVSI. Soon they will be at an equilibrium as soon as CWBHF Q-4/2023 10-K dismal returns are expected and released next month. Have Mercy WQLF oooooohA 🐺

🤓 SAID;

Well, this company has destroyed my long term interest in seeing hemp become a legitimate thriving industry. I wont be posting here anymore and am moving on…

WOLFMAN JACK SAYS; Good Riddance. Have Mercy Ahooooooo

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GE_Jim GE_Jim 1 month ago
Good luck to you as well
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DarthYoda DarthYoda 1 month ago
Well, this company has destroyed my long term interest in seeing hemp become a legitimate thriving industry. I wont be posting here anymore and am moving on to spend my time on something other than hoping for the government to fix the purposely broken hemp industry or for this company to do anything at all in the interest of its shareholders. Good luck to you guys.
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DarthYoda DarthYoda 2 months ago
https://www.charlottesweb.com/blog/cbd-oil-price-reduction
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DarthYoda DarthYoda 2 months ago
Google "Fentanyl DEA" and just look at what's been going on all over the country in just this past week...
https://www.google.com/search?q=fentanyl+DEA&sca_esv=2afe524f36ca658b&tbm=nws&source=lnms&sa=X&ved=2ahUKEwikxcG7_JyEAxVfkokEHekrAk0Q_AUoAXoECAEQAw&biw=1488&bih=790&dpr=1.25
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DarthYoda DarthYoda 2 months ago
My younger cousin died from somehow running into fentanyl back in October. Our government did that on purpose.
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DarthYoda DarthYoda 2 months ago
The problem is we don't have a legitimate government across the board and that has been the case for a long time now. I'm also convinced the entire way that public markets are set up is a purposeful scam. From the pinks to the big boards. The entire format is a joke for being 2024. L2 is a joke. Disclosure, auditing, reporting is a joke. Accountability to shareholders is a joke. SEC is a major joke. FDA needs to be prosecuted for crimes against humanity and treason. I can go on and on, but you get it.
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GE_Jim GE_Jim 2 months ago
That’s a good overview. CBD or THC, grass, the story has the same roadblocks. Doesn’t matter if its Congress, HHS, DEA, FDA, it’s all about somebody in government to sign off on it. It’s been a long road already and still many more pitfalls to go, IMO.
I do believe at some point everything will be given a green light for some real open field running, but until then were all just waiting on the government.
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DarthYoda DarthYoda 2 months ago
Ok scumbags. No more DD for you. Back to vacation.
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DarthYoda DarthYoda 2 months ago
Once again the scamming traders wait for me to post before dumping shares. Never fails. The gay corporate banking mafia strikes again.
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DarthYoda DarthYoda 2 months ago
I put very little weight on what the Feds say about rescheduling cannabis and think other bills could pass first. Probably smart to still keep an eye on those other bills.
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DarthYoda DarthYoda 2 months ago
"Federal Marijuana Banking Act Gains Three New US House Sponsors, Now Has 103":
Feb 7, 2024
Just one day after the SAFE Banking Act gained its 100th sponsor in the United States House of Representatives, three new lawmakers have joined as cosponsors.
https://themarijuanaherald.com/2024/02/federal-marijuana-banking-act-gains-three-new-us-house-sponsors-now-has-103/
https://themarijuanaherald.com/2024/02/us-house-bill-to-allow-marijuana-banking-gains-100th-sponsor/
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DarthYoda DarthYoda 2 months ago
"A summary of pending federal cannabis legislation":
February 7, 2024
https://www.reuters.com/legal/litigation/where-things-stand-summary-pending-federal-cannabis-legislation-2024-02-07/
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