FORM 4 [ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

ORTENZIO ROCCO A
2. Issuer Name and Ticker or Trading Symbol

SELECT MEDICAL HOLDINGS CORP [ SEM ]
5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__X__ Director                    _____ 10% Owner
__X__ Officer (give title below)    _____ Other (specify below)
Vice Chairman and Co-Founder
(Last)          (First)          (Middle)

C/O SELECT MEDICAL HOLDINGS CORPORATION, 4714 GETTYSBURG ROAD
3. Date of Earliest Transaction (MM/DD/YYYY)

2/8/2021
(Street)

MECHANICSBURG, PA 17055
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 2/8/2021  G  V 1445195 D$0 3804805 I By the Rocco A. Ortenzio Descendants Trust (1)
Common Stock 2/8/2021  G  V 3804805 D$0 0 I By the Rocco A. Ortenzio Descendants Trust (1)
Common Stock         1445195 (2)I By the Rocco A. Ortenzio Separate Non-Exempt Descendants Trust (1)
Common Stock         3804805 (3)I By the Rocco A. Ortenzio Separate Exempt Descendants Trust (1)
Common Stock         847143 D  
Common Stock         1178560 I By the Rocco A. Ortenzio Revocable Trust dated 8/14/07, as amended (1)
Common Stock         1242890 I By the Rocco A. Ortenzio October 2019 GRAT (1)
Common Stock         2000000 I By the Rocco A. Ortenzio July 2020 GRAT (1)
Common Stock         30601 I By Select Investments III, L.P. (1)
Common Stock         16182 I By Select AP Investors, L.P. (1)
Common Stock         10000 I By spouse (1)
Common Stock         56669 I By the Rocco A. Ortenzio 2014 Trust for Robert A. Ortenzio (1)
Common Stock         56668 I By the Rocco A. Ortenzio 2014 Trust for Martin J. Ortenzio (1)
Common Stock         56668 I By the Rocco A. Ortenzio 2014 Trust for John M. Ortenzio (1)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
6. Date Exercisable and Expiration Date7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares

Explanation of Responses:
(1) The reporting person beneficially owns the reported securities indirectly, but disclaims beneficial ownership of the reported securities except to the extent of his pecuniary interest therein.
(2) These shares were previously owned by the Rocco A. Ortenzio Descendants Trust and were transferred to the Rocco A. Ortenzio Separate Non-Exempt Descendants Trust on February 8, 2021.
(3) These shares were previously owned by the Rocco A. Ortenzio Descendants Trust and were transferred to the Rocco A. Ortenzio Separate Exempt Descendants Trust on February 8, 2021.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
ORTENZIO ROCCO A
C/O SELECT MEDICAL HOLDINGS CORPORATION
4714 GETTYSBURG ROAD
MECHANICSBURG, PA 17055
X
Vice Chairman and Co-Founder

Signatures
/s/ Michael E. Tarvin, as attorney-in-fact2/9/2021
**Signature of Reporting PersonDate

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