Agilent Announces New Ion Mobility LC/Q-TOF and Enhanced Solutions for Biotherapeutics at ASMS 2021
November 01 2021 - 8:06AM
Business Wire
Advancing biopharma and life science
research workflows
Agilent Technologies Inc. (NYSE: A) announced today the new
Agilent 6560C Ion Mobility LC/Q-TOF, enhancements to the VWorks
automation software suite, and new AssayMAP large capacity
cartridges. These solutions will be on show at the American Society
for Mass Spectrometry Conference (ASMS) which is being held October
31 - November 4, 2021, in Philadelphia, PA. These products improve
the analysis of proteins and peptides to speed up the development
of new protein-based therapeutics in biopharma.
As the market for protein biotherapeutics expands, pressure
increases to improve the efficiency and efficacy of the development
process. Researchers need more powerful, insightful instrumentation
and software, as well as automation. There is also more focus on
regulatory compliance, requiring organizations to maintain data
integrity. These new Agilent products address specific stages of
the development workflow, from sample preparation to secure
protocols, and software to complex protein structural analysis.
“By expanding our instrument portfolio, software solutions, and
sample preparation capabilities, Agilent delivers significant value
for the development of biotherapeutics in this fast-growing market,
allowing for deeper characterization of proteins,” said Sudharshana
Seshadri, vice president and general manager of Agilent’s Mass
Spectrometry Division. “These introductions reinforce Agilent’s
commitment to supporting and enhancing the speed of discovery and
development of novel protein biotherapeutics to improve the quality
of life.”
Brandon Ruotolo, professor of chemistry at University of
Michigan, agrees and is already seeing benefits from the new
Collision Induced Unfolding (CIU) capability. “The CIU technology
has been transformative for my research,” said Ruotolo. He added,
“It has greatly enhanced our ability to develop rapid, structurally
sensitive assays targeting systems ranging from large protein
assemblies to biotherapeutic antibodies. I can’t wait to see what
the future holds.”
The new 6560C Ion Mobility Q-TOF adds new capabilities that
enhance flexibility and performance over its predecessors for more
precise measurements of large protein complexes such as
biotherapeutic antibodies and large protein assemblies. Protein
folding and structural analysis are now possible by CIU, and HRdm
2.0 postprocessing generates IM resolution of up to 250.
New features of the VWorks 14.1 automation software suite
enhance support for 21 CFR Part 11 and Annex 11 with e-signatures
and secure protocols for AssayMAP. VWorks 14.1 offers seamless
adoption of automation and the Bravo platform into regulated
environments to improve sample throughput, enhance reproducibility
and reduce errors.
The AssayMAP large capacity cartridges extend the portfolio of
available chemistries with the introduction of Protein A affinity
purification cartridges and reversed phase cartridges for antibody
enrichment and peptide cleanup, respectively. These products enable
automated sample preparation upstream of multiple critical quality
analyses across the biotherapeutic development process.
ASMS attendees are invited to visit Agilent's Exhibition Booth
No. 701 at the Pennsylvania Convention Center. Agilent is a
corporate member of ASMS and a co-sponsor of the annual event.
Follow Agilent at ASMS on Twitter, using the conference hashtag:
#ASMS2021.
About Agilent Technologies
Agilent is a leader in life sciences, diagnostics, and applied
chemical markets, delivering innovative technology solutions that
provide trusted answers to researchers’ most challenging scientific
questions. The company generated revenue of $5.34 billion in fiscal
year 2020 and employs 16,400 people worldwide. Information about
Agilent is available at www.agilent.com. To receive the latest
Agilent news, please subscribe to the Agilent Newsroom. Follow
Agilent on LinkedIn, Twitter, and Facebook.
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Media Contact Naomi Goumillout Agilent Technologies
+1.781.266.2819 naomi.goumillout@agilent.com
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