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Monopar Therapeutics Inc

Monopar Therapeutics Inc (MNPR)

0.64
0.005
(0.79%)
Closed July 23 4:00PM
0.64
0.00
( 0.00% )
Pre Market: 9:07AM

Your Hub for Real-Time streaming quotes, Ideas and Live Discussions

Key stats and details

Current Price
0.64
Bid
0.6368
Ask
0.66
Volume
60
0.00 Day's Range 0.00
0.2739 52 Week Range 1.73
Market Cap
Previous Close
0.64
Open
-
Last Trade
20
@
0.6468
Last Trade Time
07:00:00
Financial Volume
-
VWAP
-
Average Volume (3m)
116,474
Shares Outstanding
17,484,175
Dividend Yield
-
PE Ratio
-1.33
Earnings Per Share (EPS)
-0.48
Revenue
-
Net Profit
-8.4M

About Monopar Therapeutics Inc

Monopar Therapeutics Inc is a clinical-stage biopharmaceutical company focused on developing proprietary therapeutics designed to extend life or improve the quality of life for cancer patients. The company's pipeline consists of?Validive?for the prevention of chemoradiotherapy-induced severe oral mu... Monopar Therapeutics Inc is a clinical-stage biopharmaceutical company focused on developing proprietary therapeutics designed to extend life or improve the quality of life for cancer patients. The company's pipeline consists of?Validive?for the prevention of chemoradiotherapy-induced severe oral mucositis in oropharyngeal cancer patients, camsirubicin?for the treatment?of advanced soft tissue sarcoma, a late-stage preclinical antibody, MNPR-101, for advanced cancers and severe COVID-19 and an early-stage camsirubicin analog, MNPR-202, for various cancers. Show more

Sector
Pharmaceutical Preparations
Industry
Pharmaceutical Preparations
Headquarters
Wilmington, Delaware, USA
Founded
1970
Monopar Therapeutics Inc is listed in the Pharmaceutical Preparations sector of the NASDAQ with ticker MNPR. The last closing price for Monopar Therapeutics was $0.64. Over the last year, Monopar Therapeutics shares have traded in a share price range of $ 0.2739 to $ 1.73.

Monopar Therapeutics currently has 17,484,175 shares outstanding. The market capitalization of Monopar Therapeutics is $11.19 million. Monopar Therapeutics has a price to earnings ratio (PE ratio) of -1.33.

MNPR Latest News

Monopar Announces First Patient Enrolled in First-in-Human Phase 1 Trial for Its Novel Radiopharmaceutical MNPR-101-Zr

WILMETTE, Ill., July 09, 2024 (GLOBE NEWSWIRE) -- Monopar Therapeutics Inc. (Nasdaq: MNPR), a clinical-stage radiopharma company focused on developing innovative treatments for cancer patients...

Monopar Announces MNPR-101-RIT Abstract Accepted as a Top-Rated Oral Presentation at EANM’24

WILMETTE, Ill., June 25, 2024 (GLOBE NEWSWIRE) -- Monopar Therapeutics Inc. (Nasdaq: MNPR), a clinical-stage radiopharma company focused on developing innovative treatments for cancer patients...

PeriodChangeChange %OpenHighLowAvg. Daily VolVWAP
1-0.099-13.39648173210.7390.750.605553830.65644454CS
4-0.1526-19.25309109260.79260.79260.605621570.70968306CS
12-0.01-1.538461538460.651.080.56511164740.7738739CS
260.252465.11867905060.38761.730.30927991131.00315512CS
52-0.1769-21.65503733630.81691.730.273916942560.92109751CS
156-4.87-88.38475499095.516.980.27396124831.00952468CS
260-23.5-97.348798674424.14480.27394303151.61922219CS

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MNPR Discussion

View Posts
PonkenPlonken PonkenPlonken 2 months ago
who killed the radiostar?
looking very great down here
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Laster Laster 2 months ago
Stock up 50% recently. Quietly moving higher.
They will report some data soon. Running in anticipation?
I like this stock a lot.
I think it has more to go.
JMO
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TIMGZ TIMGZ 5 months ago
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=173913331
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glenn1919 glenn1919 5 months ago
MNPR................................................https://stockcharts.com/h-sc/ui?s=MNPR&p=W&b=5&g=0&id=p86431144783
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Invest-in-America Invest-in-America 5 months ago
MNPR: And let alone try to explain that sudden (late-day) circa 240% soaring by @OCEA!!! And when one searches iHub's "ALL POSTS" about OCEA, one gets ambiguous posts about "Reddit was all over it", & "One guy threw $300,000 at it". BOY, that sure explains it all!!! (BONKERS STUFF, Bro!!)
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BurgerKing82 BurgerKing82 5 months ago
If there really is 15 million shares OS...That could explain the run...Granted it is a Day 2 on a Friday,the Run fizzled
🤡 1 🤮 1
BurgerKing82 BurgerKing82 5 months ago
Wow it just crashed....idk what's next
🤡 1
TimeFades TimeFades 5 months ago
Gamma squeeze
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TimeFades TimeFades 5 months ago
Still strong
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Invest-in-America Invest-in-America 5 months ago
MNPR: So am I, Dude!! NOTHING anymore makes any reasonable sense at all!!! (Their cheap FLUFF "news" of yesterday --- a mere Pre-Clinical Cancer stuff routine --- was patently UN-impressive at its core!! Yet today it soars!!)
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BurgerKing82 BurgerKing82 5 months ago
Off to a bad Start...surprised there isn't any posters,on this board...Some wild moves in either direction
🤡 1
da_stock_analyst da_stock_analyst 5 months ago
#MNPR 🔥 gap fill to $2-$3 coming? Big upside! $MNPR
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BurgerKing82 BurgerKing82 5 months ago
How many shares OS?
💩 1 🤮 1
TimeFades TimeFades 5 months ago
A lot of dumping
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TimeFades TimeFades 5 months ago
Spring tight ready for 1.5
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TimeFades TimeFades 5 months ago
Yup keeps popping off trend line
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Invest-in-America Invest-in-America 5 months ago
MNPR: You yourself have posted this sentiment countless times, Boss!!! NONE of this 'Wall Street' stuff makes ANY (rational) sense at all!!!
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TheFinalCD TheFinalCD 5 months ago
yep and still goin
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Invest-in-America Invest-in-America 5 months ago
MNPR: The obvious WINNER of this day!!! (And all behind a mere PHASE-1 Cancer study routine!!! How the fluck can anyone call this stuff???!!!)
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TimeFades TimeFades 5 months ago
Level 2 just switched bullish
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Awl416 Awl416 5 months ago
Monopar Announces Promising Preclinical Data for its MNPR-101 Radiopharma Program Targeting Advanced Cancers
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Invest-in-America Invest-in-America 5 months ago
MNPR: WOW!! I hear-ya behind ALL of those notes, Boss!!! (And heck, I wouldn't mind being YOUR son --- his favorite 'WHEELS' is that red VET, no doubt??? Or, he's already FLIPPED a stock by himself, & bought his OWN Vet??? Naturally!!!)
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TheFinalCD TheFinalCD 5 months ago
OH IVE BEEN BURNT BAD BEFORE

I WAS JUST TELLING MY 17YR OLD SON WHO I AM TEACHING HIM ABOUT THE MARKET

I TOLD HIM I LOST -$80K ON A PHASE 1 THAT GAPPED AND TRAPPED ME AND SO MANY OTHERS

THAT WAS BRUTAL


AND I DID IT A FEW TIMES AFTER, THEN GAVE UP ON PHASE 1 STOCKS
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Fredric Fredric 5 months ago
💪🏿
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Invest-in-America Invest-in-America 5 months ago
MNPR: Well then, CONGRATS to ya, Dude!!! (& GOD BLESS!!!)
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Fredric Fredric 5 months ago
Yet n still I made money. You're expecting to much.

Just take your profits n let it be. Arguing about it isn't gonna change that.the price is going back up
N my free shares looking good

Learn to have fun. Not cry. We know companies send out pr to stop the bleeding n gain investors attention

That's why we invest.we don't marry. Everyone wants money.

Take it accordingly

Good day sir. I'm off to the next investment
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Invest-in-America Invest-in-America 5 months ago
MNPR: There was NOTHING to be made in the Pre-Market, either, Clown behind this scam!!! In case you didn't know that!!!
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Fredric Fredric 5 months ago
Took original plus extra holding a few for just in case.

That's how u trade
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Fredric Fredric 5 months ago
Riding free shares
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Fredric Fredric 5 months ago
Smh 🤦🏿‍♂️ HOMEBOY

You missed the point. Keep up.. Best bet is to trade with the big boys premarket in sell at open

Or buy after hours sell at premarket or open.

Flip in the case of last minute pr

Stop looking for a reason to argue

No one will listen to your rubbish

We don't need your explanation. Just say what you gotta say n leave it at that
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Invest-in-America Invest-in-America 5 months ago
MNPR: Myself, I am NOT "embarrassed", because I wasn't dumb enough to even THINK about buying this baloney sandwich (Pre-Colombian-Technology) "News". And certainly YOU --- Admiral TFCD --- weren't stupid enough either.
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Invest-in-America Invest-in-America 5 months ago
MNPR: And that "bet" is now OVER, Homeboy!! (Cheap --- merely Phase-1 "news" --- & still hyping old RADIATION gadgets!!! Stay AWAY from this kind of Pre-Colombian medical "technology"!!!)
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Fredric Fredric 5 months ago
Best bet
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Invest-in-America Invest-in-America 5 months ago
MNPR: This type of LAST MINUTE news is deliberately launched as such --- as if everyone doesn't yet know that. (HA-HAAAA!! Flip it really QUICK, if ya all grabbed some of this clever PR launch!!)
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Fredric Fredric 5 months ago
We will see
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Fredric Fredric 5 months ago
I hate when halts. Its gonna one of those days

Instituionals halting to take profit

It willhold for while think we see 1000% minimum

I was hoping for 50$ runner on strength n hype.but if they keep halting it we will see 10 -15$

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TheFinalCD TheFinalCD 5 months ago
LETS SEE IF THIS HOLDS OR ANOTHER ALL DAY FADER???
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Fredric Fredric 5 months ago
👀 very
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Fredric Fredric 5 months ago
Premarket is always where the big money buy and sell.
We must trade accordingly.

This is no different. Just gott get in where we fit in
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TheFinalCD TheFinalCD 5 months ago
ITS FLYING BUT BE CAREFUL iVE LOST SO MUCH $$$$ ON PHASE 1 PREMARKET PUMPS

IM EMBARRASSED



https://www.globenewswire.com/news-release/2024/02/20/2831765/0/en/Monopar-Receives-Clearance-to-Proceed-with-First-in-Human-Phase-1-Trial-of-Novel-Radiopharmaceutical-MNPR-101-Zr-in-Advanced-Cancers.html
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Awl416 Awl416 5 months ago
Wild
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Fredric Fredric 5 months ago
Could be an interesting opener. Very good news lets see how the crowd reacts.

Some interest premarket

Might see nice jump at open with these cheap prices
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Awl416 Awl416 5 months ago
Monopar Receives Clearance to Proceed with First-in-Human Phase 1 Trial of Novel Radiopharmaceutical MNPR-101-Zr in Advanced Cancers
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subslover subslover 9 months ago
Monopar Presents Data Showing Tumor Reduction Benefit of Camsirubicin from Ongoing Phase 1b at the 2023 Connective Tissue Oncology Society (CTOS) Annual Meeting
WILMETTE, Ill., Nov. 01, 2023 (GLOBE NEWSWIRE) -- Monopar Therapeutics Inc. (Nasdaq: MNPR), a clinical-stage biopharmaceutical company focused on developing proprietary therapeutics designed to extend life or improve the quality of life for cancer patients, will present data from its ongoing Phase 1b open-label, dose-escalating clinical trial of camsirubicin in patients with advanced soft tissue sarcoma (ASTS) later today at the 2023 Connective Tissue Oncology Society (CTOS) Annual Meeting, which is bringing together the world’s leading sarcoma specialists. Monopar’s poster presentation can be found at the following link: https://www.monopartx.com/pipeline/Camsirubicin/mnpr-201-001-clinical-trial.

Clinical Trial Results To-Date

The Phase 1b clinical trial has enrolled 14 ASTS patients (9 female and 5 male) to-date ranging in age from 26 to 81 years (median = 52.5 years) across five dose cohorts. The trial is currently ongoing and is in the fifth dose level cohort (650 mg/m2).

So far, 9 out of the 14 patients have had stable disease (SD, as defined by RECIST 1.1 criteria) after camsirubicin treatment. All patients in the fourth and fifth cohorts achieved stable disease, including the three most recently treated patients, each of whom also experienced an ~20% tumor size reduction at last study scan. One of these patients had unresectable cancer at study entry, but after the tumor size reduction, the patient became eligible for resection and underwent successful surgical removal of their cancer with clear margins.

No dose-limiting toxicity, as defined in the protocol, has been observed to-date. A medically complex patient in the 650 mg/m2 dose cohort has an ongoing left ventricular ejection fraction (LVEF) decrease that is being monitored. This patient has a BMI of 42.5, one kidney, hypertension, a long standing heart murmur, and a maternal history of heart failure. No toxicities have occurred requiring expansion of a dose cohort, and the maximum tolerated dose (MTD) has not been reached.

Camsirubicin Background

ASTS is a deadly cancer with inadequate treatment options. Doxorubicin is currently the first-line standard of care treatment for most types of ASTS, and the average life expectancy from time of diagnosis for these patients is only about 12 to 15 months. Because of the risk of irreversible heart damage, patients discontinue doxorubicin treatment after just 6 to 8 cycles. Camsirubicin was designed to retain the anti-cancer activity while avoiding the irreversible heart damage that is seen with doxorubicin. The value-driving hypothesis for camsirubicin is straightforward: modifying doxorubicin to reduce cardiac damage could enable both higher and longer dosing, resulting in better efficacy and patient outcomes.
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Monksdream Monksdream 10 months ago
MNPR new 52 week low
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Monksdream Monksdream 11 months ago
MNPR new 52 week low
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subslover subslover 12 months ago
Monopar Provides Encouraging Camsirubicin Clinical Data Update
WILMETTE, Ill., Aug. 08, 2023 (GLOBE NEWSWIRE) -- Monopar Therapeutics Inc. (Nasdaq: MNPR), a clinical-stage biopharmaceutical company focused on developing innovative treatments for cancer, today provided an update from its currently enrolling multi-center open-label Phase 1b clinical trial of camsirubicin in patients with advanced soft tissue sarcoma (ASTS). Both patients treated to date at the 650 mg/m2 dose level have experienced tumor size reductions – of 18% and 20% respectively – after the first two cycles of camsirubicin treatment. Both patients are set to receive additional cycles of camsirubicin treatment, as well, which may result in further tumor size reduction.

The Phase 1b clinical trial data is continuing to support Monopar’s dose-response hypothesis with camsirubicin. The best response seen prior to the current 650 mg/m2 dose level was at the immediately prior dose level (520 mg/m2), which was a 21% reduction in tumor size in a patient after receiving six cycles of camsirubicin treatment. This patient’s cancer was unresectable at study entry, but after the tumor size reduction, became eligible and the patient underwent successful surgical removal of their cancer with clear margins. Furthermore, all three patients at the 520 mg/m2 dose level achieved stable disease and had either a net reduction or no overall change in tumor size per RECIST 1.1 while on study drug.

Additionally, no drug­related cardiotoxicity has been observed in the trial to date as evaluated by the industry standard left ventricular ejection fraction (LVEF), and no toxicities have been experienced by any patient that have required expanding the size of a dose cohort. Further, 71% of camsirubicin patients have experienced no hair loss, and only approximately 14% have experienced >50% hair loss, with the remainder having low grade hair loss. This compares favorably to the approximately 50% of doxorubicin treated patients in recent ASTS clinical trials reporting some amount of hair loss, with the majority of these patients experiencing >50% hair loss. Only 14% of camsirubicin patients in the Phase 1b trial have experienced mild-to-severe oral mucositis. This compares favorably to the roughly 35-40% of doxorubicin-treated patients in recent ASTS clinical trials that experienced mild-to-severe oral mucositis.

ASTS is a deadly cancer with inadequate treatment options. Doxorubicin is currently the first-line standard of care treatment for most types of ASTS, and the average life expectancy from time of diagnosis for these patients is only about 12 to 15 months. Because of the risk of irreversible heart damage, patients discontinue doxorubicin treatment after just 6 to 8 cycles. Camsirubicin has been designed to retain the anti-cancer activity while avoiding the irreversible heart damage that is seen with doxorubicin. The value-driving hypothesis for camsirubicin is straightforward: modifying doxorubicin in order to reduce cardiac damage could enable higher and longer dosing, resulting in better efficacy and patient outcomes.

Camsirubicin Clinical Trial Design and GEIS Collaboration

The purpose of this dose escalation Phase 1b trial is to determine the maximum tolerated dose (MTD) of camsirubicin. Once the MTD is reached, Monopar has a clinical collaboration agreement in place with the Spanish Sarcoma Group (Grupo Español de Investigación en Sarcomas, or GEIS) to conduct a multi-country randomized Phase 2 clinical trial. The Phase 2 plan is to evaluate camsirubicin head-to-head against doxorubicin in patients with ASTS, with GEIS as the study sponsor with support from Monopar.

Further information about this actively enrolling, open-label, dose-escalation Phase 1b clinical trial is available at www.ClinicalTrials.gov under study identifier NCT 05043649.

About Monopar Therapeutics Inc.

Monopar Therapeutics is a clinical­stage biopharmaceutical company focused on developing innovative treatments for cancer patients. Monopar's pipeline consists of camsirubicin (Phase 1b) for the treatment of advanced soft tissue sarcoma; MNPR­101, a late­stage preclinical antibody for radiopharmaceutical use in advanced cancers; and MNPR­202, an early­stage camsirubicin analog for various cancers. For more information, visit: www.monopartx.com.

Forward-Looking Statements

Statements contained in this press release regarding matters that are not historical facts are "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. The words “may,” “will,” “could,” “would,” “should,” “expect,” “plan,” “anticipate,” “intend,” “believe,” “estimate,” “predict,” “project,” “potential,” “continue,” “target” and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Examples of these forward-looking statements include statements concerning: that additional cycles of camsirubicin treatment may result in further tumor size reduction; that the hypothesis for camsirubicin is straightforward: modifying doxorubicin in order to reduce cardiac damage could enable higher and longer dosing, resulting in better efficacy and patient outcomes; and Monopar’s plans to conduct a multi-country randomized Phase 2 clinical trial once the MTD is reached evaluating camsirubicin head-to-head against doxorubicin in patients with ASTS, with GEIS as the study sponsor with support from Monopar. The forward-looking statements involve risks and uncertainties including, but not limited to: the camsirubicin Phase 1b trial not proving safety and efficacy at higher doses; not successfully recruiting additional patients and initiating additional clinical trial sites for the camsirubicin Phase 1b clinical trial within expected timeframes, if at all; the Company’s inability to raise sufficient funds or engage a partner to continue the camsirubicin clinical program beyond the Phase 1b clinical trial; GEIS not conducting the camsirubicin Phase 2 clinical trial; and the significant general risks and uncertainties surrounding the research, development, regulatory approval, and commercialization of therapeutics. Actual results may differ materially from those expressed or implied by such forward-looking statements. Risks are described more fully in Monopar's filings with the Securities and Exchange Commission. All forward-looking statements contained in this press release speak only as of the date on which they were made. Monopar undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made. Any forward-looking statements contained in this press release represent Monopar’s views only as of the date hereof and should not be relied upon as representing its views as of any subsequent date.

CONTACT:??

Monopar Therapeutics Inc.
Investor Relations??
Kim R. Tsuchimoto??
Chief Financial Officer??
kimtsu@monopartx.com

Follow Monopar on social media for updates:?
Twitter: @MonoparTx? LinkedIn: Monopar Therapeutics

https://www.globenewswire.com/newsroom/ti?nf=ODg4OTAzMyM1NzQxNzkxIzIxOTM4NjM=
https://ml.globenewswire.com/media/Mjc5OTExN2QtZGQwZC00YTgxLTk3OGUtMzA0ZDk0MmY4YjU1LTEyMDU0MTY=/tiny/Monopar-Therapeutics-Inc-.png

Source: Monopar Therapeutics Inc.
© 2023 GlobeNewswire, Inc.
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AJ Freely AJ Freely 12 months ago
$MNPR - 👆Up 9.9% Pre-Market/ Current Price $0.83
Monopar Provides Encouraging Camsirubicin Clinical Data Update
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retireat40 retireat40 1 year ago
1.00 right now
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Monksdream Monksdream 1 year ago
MNPR new 52 week low
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