Lexicon Pharmaceuticals to Host Conference Call and Webcast Today, March 22, 2019 to Provide a Regulatory Update on Sotaglifl...
March 22 2019 - 2:16PM
Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) today announced that
management will conduct a conference call and live webcast today,
Friday, March 22, 2019, at 2:45 p.m. EDT (1:45 p.m. CDT) to provide
a regulatory update on sotagliflozin, an investigational oral
treatment for adults with type 1 diabetes, and to discuss next
steps for the sotagliflozin program.
Dial-in InformationU.S. Dial-in
Number: (888) 645-5785International Dial-in Number:
(970) 300-1531Conference ID: 6163588
Replay InformationU.S. Dial-in
Number: (855) 859-2056Replay International Dial-in
Number: (404) 537-3406Conference ID: 6163588
The dial-in replay will be available for 14 days
following the call. An audio webcast will be available online in
the investor relations section of the company website at
www.lexpharma.com/investors, with a webcast replay accessible for
14 days after the call.
About Sotagliflozin
Discovered using Lexicon’s unique approach to
gene science, sotagliflozin is an investigational oral dual
inhibitor of two proteins responsible for glucose regulation known
as sodium-glucose co-transporter types 1 and 2 (SGLT1 and SGLT2).
SGLT1 is responsible for glucose absorption in the gastrointestinal
tract, and SGLT2 is responsible for glucose reabsorption by the
kidney.
Lexicon entered into a collaboration and license
agreement with Sanofi in November 2015 under which Lexicon granted
Sanofi an exclusive, worldwide (excluding Japan), royalty-bearing
right and license to develop, manufacture and commercialize
sotagliflozin. Lexicon is responsible for all clinical development
activities relating to type 1 diabetes and has exercised an
exclusive option to co-promote and have a significant role, in
collaboration with Sanofi, in the commercialization of
sotagliflozin for the treatment of type 1 diabetes in the U.S.
Sanofi is responsible for all clinical development and
commercialization of sotagliflozin for the treatment of type 2
diabetes worldwide (excluding Japan) and is solely responsible for
the commercialization of sotagliflozin for the treatment of type 1
diabetes outside the U.S. (excluding Japan).
Sanofi has received a complete response letter
from the U.S. Food and Drug Administration regarding its New Drug
Application (NDA) for sotagliflozin in type 1 diabetes. The
European Medicines Agency’s Committee for Medicinal Products for
Human Use (CHMP) has adopted a positive opinion on the Marketing
Authorization Application (MAA) for sotagliflozin as an adjunct to
insulin therapy to improve blood sugar (glycemic) control in adults
with type 1 diabetes mellitus with a body mass index (BMI) ≥ 27
kg/m2, who have failed to achieve adequate glycemic control despite
optimal insulin therapy; the European Commission is expected to
make a final decision on the MAA in the coming months.
Sotagliflozin is in Phase 3 development for type 2 diabetes.
Sotagliflozin has not yet been approved for use in either type 1 or
type 2 diabetes in the U.S., Europe or any other jurisdiction.
About Lexicon
Pharmaceuticals
Lexicon is a fully integrated biopharmaceutical
company that is applying a unique approach to gene science based on
Nobel Prize-winning technology to discover and develop precise
medicines for patients with serious, chronic conditions. Through
its Genome5000™ program, Lexicon scientists have studied the role
and function of nearly 5,000 genes over the last 20 years and have
identified more than 100 protein targets with significant
therapeutic potential in a range of diseases. Through the precise
targeting of these proteins, Lexicon is pioneering the discovery
and development of innovative medicines to safely and effectively
treat disease. In addition to its first commercial product,
XERMELO® (telotristat ethyl), Lexicon has a
pipeline of promising drug candidates in clinical and pre-clinical
development in diabetes and metabolism and neuropathic pain. For
additional information please visit www.lexpharma.com.
Safe Harbor Statement
This press release contains “forward-looking
statements,” including statements relating to Lexicon’s growth and
future operating results, discovery and development of products,
strategic alliances and intellectual property, as well as other
matters that are not historical facts or information. All
forward-looking statements are based on management’s current
assumptions and expectations and involve risks, uncertainties and
other important factors, specifically including those relating to
Lexicon’s ability to meet its capital requirements, successfully
conduct preclinical and clinical development of its drug
candidates, obtain necessary regulatory approvals, achieve its
operational objectives, obtain patent protection for its
discoveries and establish strategic alliances, as well as
additional factors relating to manufacturing, intellectual property
rights, and the therapeutic or commercial value of its drug
candidates, that may cause Lexicon’s actual results to be
materially different from any future results expressed or implied
by such forward-looking statements. Information identifying
such important factors is contained under “Risk Factors” in
Lexicon’s annual report on Form 10-K for the year ended December
31, 2018, as filed with the Securities and Exchange
Commission. Lexicon undertakes no obligation to update or
revise any such forward-looking statements, whether as a result of
new information, future events or otherwise.
For Investor Inquiries:
Kimberly Lee, D.O.Head of Investor Relations and
Corporate StrategyLexicon Pharmaceuticals(281)
863-3383klee@lexpharma.com
For Media Inquiries:
Chas SchultzExecutive Director, Corporate
Communications and Patient AdvocacyLexicon Pharmaceuticals(281)
863-3421cschultz@lexpharma.com
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