By Colin Kellaher

 

Bristol-Myers Squibb Co. and Exelixis Inc. on Monday said a pivotal phase 3 study evaluating Opdivo in combination with Cabometyx compared to sunitinib in previously untreated advanced or metastatic renal-cell carcinoma met its key endpoints.

The companies said the study met the primary endpoint of progression-free survival at final analysis, along with the secondary endpoints of overall survival at a pre-specified interim analysis and objective response rate.

The companies said the combination Bristol's Opdivo and Exelixis' Cabometyx showed a favorable safety profile and could become an important new first-line option for patients with metastatic renal-cell carcinoma, the most common type of kidney cancer in adults.

 

Write to Colin Kellaher at colin.kellaher@wsj.com

 

(END) Dow Jones Newswires

April 20, 2020 07:35 ET (11:35 GMT)

Copyright (c) 2020 Dow Jones & Company, Inc.
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