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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 10-Q
(Mark One)
QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the quarterly period ended March 31, 2022

-OR-
TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

Commission File Number: 001-34885

AMYRIS, INC.
(Exact name of registrant as specified in its charter) 
Delaware
55-0856151
(State or other jurisdiction of
incorporation or organization)
(I.R.S. Employer
Identification No.)
Amyris, Inc.
5885 Hollis Street, Suite 100
Emeryville, CA 94608
(510) 450-0761
(Address and telephone number of principal executive offices)

Securities registered pursuant to Section 12(b) of the Act:
Title of each classTrading Symbol(s)Name of each exchange on which registered
Common Stock, $0.0001 par value per shareAMRSThe Nasdaq Stock Market LLC

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.    Yes  ☒    No  ☐

Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit such files).    Yes  ☒    No  ☐

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and "emerging growth company" in Rule 12b-2 of the Exchange Act.
Large accelerated filer
Accelerated filer
Non-accelerated filerSmaller reporting company
Emerging growth company

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes ☐  No ☒

Shares outstanding of the Registrant's common stock:
Class
Outstanding as of May 3, 2022
Common Stock, $0.0001 par value per share
319,714,436




AMYRIS, INC.
TABLE OF CONTENTS
Page
PART I
Item 1.
Item 2.
Item 3.
Item 4.
PART II
Item 1.
Item 1A.
Item 2.
Item 3.
Item 4.
Item 5.
Item 6.







2



PART I
ITEM 1. FINANCIAL STATEMENTS (UNAUDITED)
AMYRIS, INC.
CONDENSED CONSOLIDATED BALANCE SHEETS
(Unaudited)
(In thousands, except shares and per share amounts)March 31,
2022
December 31, 2021
Assets
Current assets:
Cash and cash equivalents$287,886 $483,462 
Restricted cash174 199 
Accounts receivable, net of allowance of $965 and $945, respectively
37,400 37,074 
Accounts receivable - related party, net of allowance of $0 and $0, respectively
7,279 5,667 
Contract assets3,883 4,227 
Contract assets - related party8,816 — 
Inventories82,296 75,070 
Prepaid expenses and other current assets43,202 33,513 
Total current assets470,936 639,212 
Property, plant and equipment, net125,264 72,835 
Restricted cash, noncurrent4,651 4,651 
Recoverable taxes from Brazilian government entities22,572 16,740 
Right-of-use assets under financing leases, net457 7,342 
Right-of-use assets under operating leases, net58,937 32,428 
Goodwill136,005 131,259 
Intangible assets, net56,094 39,265 
Other assets23,534 10,566 
Total assets$898,450 $954,298 
Liabilities, Mezzanine Equity and Stockholders' (Deficit) Equity
Current liabilities:
Accounts payable$88,292 $79,666 
Accrued and other current liabilities80,554 71,457 
Financing lease liabilities12 140 
Operating lease liabilities8,120 7,689 
Contract liabilities1,554 2,530 
Debt, current portion1,055 896 
Related party debt, current portion (includes instrument measured at fair value of $86,630 and $107,427, respectively)
86,630 107,427 
Total current liabilities266,217 269,805 
Long-term debt, net of current portion672,005 309,061 
Financing lease liabilities, net of current portion58 61 
Operating lease liabilities, net of current portion37,059 19,829 
Derivative liabilities5,247 7,062 
Acquisition-related contingent consideration (Note 3 and Note 7)40,251 64,762 
Other noncurrent liabilities3,490 4,510 
Total liabilities1,024,327 675,090 
Commitments and contingencies
Mezzanine equity:
Contingently redeemable common stock5,000 5,000 
Contingently redeemable noncontrolling interest31,437 28,520 
Stockholders’ (deficit) equity:
Preferred stock - $0.0001 par value, 5,000,000 shares authorized as of March 31, 2022 and December 31, 2021; zero shares issued and outstanding as of March 31, 2022 and December 31, 2021
— — 
Common stock - $0.0001 par value, 450,000,000 shares authorized as of March 31, 2022 and December 31, 2021; 317,975,269 and 308,899,906 shares issued and outstanding as of March 31, 2022 and December 31, 2021, respectively
32 31 
Additional paid-in capital2,337,634 2,656,838 
Accumulated other comprehensive loss(37,483)(52,769)
Accumulated deficit(2,458,973)(2,357,661)
Total Amyris, Inc. stockholders’ (deficit) equity(158,790)246,439 
Noncontrolling interest(3,524)(751)
Total stockholders' (deficit) equity(162,314)245,688 
Total liabilities, mezzanine equity and stockholders' (deficit) equity$898,450 $954,298 

See the accompanying notes to the unaudited condensed consolidated financial statements.






3



AMYRIS, INC.
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
(Unaudited)
Three Months Ended March 31,
(In thousands, except shares and per share amounts)20222021
Revenue:
Renewable products (includes related party revenue of $4,412 and $1,662, respectively)
$43,465 $28,179 
Licenses and royalties (includes related party revenue of $8,816 and $143,612, respectively)
9,313 143,800 
Collaborations, grants and other (includes related party revenue of $2,000 and $2,000, respectively)
4,931 4,880 
Total revenue (includes related party revenue of $15,228 and $147,274, respectively)
57,709 176,859 
Cost and operating expenses:
Cost of products sold48,995 22,659 
Research and development26,358 23,332 
Sales, general and administrative106,916 37,922 
Total cost and operating expenses182,269 83,913 
(Loss) income from operations(124,560)92,946 
Other income (expense):
Interest expense(5,263)(5,813)
Gain (loss) from change in fair value of derivative instruments1,815 (22,745)
Gain (loss) from change in fair value of debt20,796 (326,785)
Loss upon extinguishment of debt— (27,313)
Other expense, net(3,052)(678)
Total other income (expense), net14,296 (383,334)
Loss before income taxes and loss from investment in affiliate(110,264)(290,388)
Benefit from (provision for) income taxes820 (55)
(Loss) income from investment in affiliate(789)392 
Net loss(110,233)(290,051)
Loss (income) attributable to noncontrolling interest2,928 (1,200)
Net loss attributable to Amyris, Inc.(107,305)(291,251)
Less: loss allocated to participating securities— 2,099 
Net loss attributable to Amyris, Inc. common stockholders, basic$(107,305)$(289,152)
Net loss per share attributable to common stockholders, basic$(0.34)$(1.08)
Weighted-average shares of common stock outstanding used in computing net loss per share of common stock, basic312,896,452 267,733,555 
Net loss per share attributable to common stockholders, diluted$(0.37)$(1.08)
Weighted-average shares of common stock outstanding used in computing net loss per share of common stock, diluted323,711,682 267,733,555 

See the accompanying notes to the unaudited condensed consolidated financial statements.






4




AMYRIS, INC.
CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS
(Unaudited)

Three Months Ended March 31,
(In thousands)20222021
Comprehensive loss:
Net loss$(110,233)$(290,051)
Foreign currency translation adjustment15,286 (2,038)
Total comprehensive loss(94,947)(292,089)
Loss (income) attributable to noncontrolling interest2,928 (1,200)
Comprehensive loss attributable to Amyris, Inc.$(92,019)$(293,289)

See the accompanying notes to the unaudited condensed consolidated financial statements.






5



AMYRIS, INC.
CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (DEFICIT)
AND MEZZANINE EQUITY
(Unaudited)

Preferred StockCommon Stock
(In thousands, except number of shares)SharesAmountSharesAmountAdditional Paid-in CapitalAccumulated Other Comprehensive LossAccumulated DeficitNoncontrolling InterestTotal Stockholders' DeficitMezzanine Equity - Contingently Redeemable Common Stock Mezzanine Equity - Contingently Redeemable Noncontrolling Interest
Balances at December 31, 2021 $ 308,899,906 $31 $2,656,838 $(52,769)$(2,357,661)$(751)$245,688 $5,000 $28,520 
Cumulative effect of change in accounting principle for ASU 2020-06 (see "Significant Accounting Policies" in Note 1)— — — — (367,974)— 5,993 — (361,981)— — 
Acquisitions— — — — — — — 155 155 — 2,917 
Issuance of common stock and payment of minimum employee taxes withheld upon net share settlement of restricted stock— — 528,704 — (3)— — — (3)— — 
Issuance of common stock as purchase consideration in business combinations— — 7,121,806 33,093 — — — 33,094 — — 
Issuance of common stock upon exercise of stock options— — 33,250 — 98 — — — 98 — — 
Issuance of common stock upon exercise of warrants— — 1,391,603 — 3,994 — — — 3,994 — — 
Stock-based compensation— — — — 11,588 — — — 11,588 — — 
Foreign currency translation adjustment— — — — — 15,286 — — 15,286 — — 
Net loss attributable to Amyris, Inc.— — — — — — (107,305)(2,928)(110,233)— — 
Balances as of March 31, 2022 $ $317,975,269 $32 $2,337,634 $(37,483)$(2,458,973)$(3,524)$(162,314)$5,000 $31,437 
Balances at December 31, 20208,280 $ 244,951,446 $24 1,957,224 $(47,375)$(2,086,692)$4,774 $(172,045)$5,000 $ 
Issuance of common stock and payment of minimum employee taxes withheld upon net share settlement of restricted stock— — 496,341 — (2)— — — (2)— — 
Issuance of common stock upon conversion of debt principal, net of 2,600,000 pre-delivery shares returned to Amyris
— — 5,827,164 110,574 — — — 110,575 — — 
Issuance of common stock upon exercise of stock options— — 377,542 — 1,920 — — — 1,920 — — 
Issuance of common stock upon exercise of warrants— — 15,557,480 32,217 — — — 32,219 — — 
Issuance of common stock upon exercise of warrants - related party— — 6,056,944 — — — — — — — — 
Stock-based compensation— — — — 4,281 — — — 4,281 — — 
Foreign currency translation adjustment— — — — (2,038)— — (2,038)— — 
Net loss attributable to Amyris, Inc.— — — — — $(291,251)$1,200 (290,051)— $— 
Balances at March 31, 20218,280 $ $273,266,917 $27 $2,106,214 $(49,413)$(2,377,943)$5,974 $(315,141)$5,000 $ 

See the accompanying notes to the unaudited condensed consolidated financial statements.






6



AMYRIS, INC.
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
(Unaudited)
Three Months Ended March 31,
(In thousands)20222021
Operating activities
Net loss$(110,233)$(290,051)
Adjustments to reconcile net loss to net cash used in operating activities:
Accretion of debt discount962 713 
Amortization of intangible assets892 — 
Amortization of right-of-use assets under operating leases754 750 
Depreciation and amortization2,400 2,114 
(Gain) loss from change in fair value of debt(20,796)326,785 
(Gain) loss from change in fair value of derivative instruments(1,815)22,745 
Loss (gain) from investment in affiliate789 (392)
Loss on foreign currency exchange rates1,519 408 
Loss upon extinguishment of debt— 27,313 
Stock-based compensation11,588 4,281 
Changes in assets and liabilities:
Accounts receivable(1,554)17,275 
Contract assets(8,472)(3,208)
Inventories(5,001)(5,686)
Deferred cost of products sold - related party— 5,129 
Prepaid expenses and other assets(23,881)(8,207)
Accounts payable5,007 4,154 
Accrued and other liabilities6,026 4,011 
Lease liabilities(9,658)(1,185)
Contract liabilities(969)1,702 
Net cash provided by (used in) operating activities(152,442)108,651 
Investing activities
Purchases of property, plant and equipment(33,751)(2,493)
Acquisitions, net of cash acquired(13,535)— 
Net cash used in investing activities(47,286)(2,493)
Financing activities
Issuance costs incurred in connection with debt modification— (2,500)
Payment of minimum employee taxes withheld upon net share settlement of restricted stock units(3)(2)
Principal payments on debt— (23,196)
Principal payments on financing leases(131)(912)
Proceeds from exercises of common stock options98 1,920 
Proceeds from exercises of warrants3,994 32,219 
Net cash provided by financing activities3,958 7,529 
Effect of exchange rate changes on cash, cash equivalents and restricted cash169 (44)
Net increase in cash, cash equivalents and restricted cash(195,601)113,643 
Cash, cash equivalents and restricted cash at beginning of period488,312 31,422 
Cash, cash equivalents and restricted cash at end of the period$292,711 $145,065 
Reconciliation of cash, cash equivalents and restricted cash to the condensed consolidated balance sheets
Cash and cash equivalents$287,886 $143,821 
Restricted cash, current174 283 
Restricted cash, noncurrent4,651 961 
Total cash, cash equivalents and restricted cash$292,711 $145,065 

See the accompanying notes to the unaudited condensed consolidated financial statements.






7



AMYRIS, INC.
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS, Continued
(Unaudited)
Three Months Ended March 31,
(In thousands)20222021
Supplemental disclosures of cash flow information:
Cash paid for interest$52 $3,275 
Supplemental disclosures of non-cash investing and financing activities:
Acquisition of intangible assets in connection with business combinations$18,417 $— 
Acquisition of right-of-use assets under operating leases$27,165 $— 
Common stock and warrants issued in exchange for debt principal and accrued interest reduction$— $110,575 
Common stock issued as purchase consideration in business combinations$33,094 $— 
Derecognition of derivative liabilities to equity upon extinguishment of debt$— $59 
Goodwill recorded in connection with business combinations$7,666 $— 
Noncontrolling interest recorded in connection with business combinations$3,072 $— 
Unpaid property, plant and equipment balances in accounts payable and accrued liabilities at end of period$4,995 $1,121 

See the accompanying notes to the unaudited condensed consolidated financial statements.






8



AMYRIS, INC.
NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
(Unaudited)

1. Basis of Presentation and Summary of Significant Accounting Policies

Amyris, Inc. and subsidiaries (collectively, Amyris or the Company) is a biotechnology company delivering sustainable solutions for people and the planet. The Company creates, manufactures and commercializes consumer products and ingredients. Currently, the largest driver of the Company's revenue is derived from marketing and selling Clean Beauty, Personal Care and Health & Wellness consumer products through direct-to-consumer ecommerce platforms and a growing network of retail partners. The Company also sells sustainable ingredients to sector leaders that serve Flavor & Fragrance (F&F), Nutrition, Food & Beverage, and Clean Beauty & Personal Care end markets. The Company's ingredients and consumer products are powered by the Company's fermentation-based Lab-to-MarketTM technology platform, which leverages state-of-the-art machine learning, robotics and artificial intelligence, enabling the Company to rapidly bring new innovation to market.

The accompanying unaudited condensed consolidated financial statements of Amyris, Inc. should be read in conjunction with the audited consolidated financial statements and notes thereto included in the Company's Annual Report on Form 10-K for the year ended December 31, 2021 (the 2021 Form 10-K), from which the condensed consolidated balance sheet as of December 31, 2021 is derived. The accompanying condensed consolidated financial statements have been prepared in accordance with U.S. generally accepted accounting principles (U.S. GAAP) for interim financial information and with the instructions to Form 10-Q and Article 10 of Regulation S-X. Accordingly, the accompanying interim condensed consolidated financial statements do not include all the information and notes required by U.S. GAAP for complete financial statements. The accompanying condensed consolidated financial statements reflect all adjustments, consisting of normal recurring adjustments, that are, in the opinion of management, necessary to a fair statement of the results for the interim periods presented. Interim results are not necessarily indicative of results for a full year.

Significant Accounting Policies

Note 1, "Basis of Presentation and Summary of Significant Accounting Policies", to the audited consolidated financial statements in the 2021 Form 10-K includes a discussion of the significant accounting policies and estimates used in the preparation of the Company’s condensed consolidated financial statements. There have been no material changes to the Company's significant accounting policies and estimates during the three months ended March 31, 2022.

Use of Estimates and Judgements

The preparation of financial statements in conformity with U.S. GAAP requires management to make estimates, judgements and assumptions that affect the reported amounts of assets and liabilities, disclosures of contingent assets and liabilities at the date of the financial statements, and the reported amounts of revenues and expenses during the reporting period. Actual results could differ from those estimates, and such differences may be material to the condensed consolidated financial statements. Significant estimates and judgements used in these consolidated financial statements are discussed in the relevant accounting policies below or specifically discussed in the Notes to Consolidated Financial Statements where such transactions are disclosed.






9




Accounting Update Recently Adopted

In the three months ended March 31, 2022, the Company adopted this accounting update:

Convertible Debt, and Derivatives and Hedging. In August 2020, the FASB issued ASU 2020-06, Debt—Debt with Conversion and Other Options (Subtopic 470-20) and Derivatives and Hedging—Contracts in Entity’s Own Equity (Subtopic 815-40): Accounting for Convertible Instruments and Contracts in an Entity’s Own Equity, to improve financial reporting associated with accounting for convertible instruments and contracts in an entity’s own equity. ASU 2020-06 became effective for the Company in the first quarter of 2022. Adoption of this standard on January 1, 2022 in connection with the 2026 Convertible Senior Notes (see Note 4, "Debt"), decreased additional paid-in capital by $368.0 million, increased debt by the same amount and decreased accumulated deficit by $6.0 million for debt discount accretion expense that was recorded prior to adoption.

Accounting Standards or Updates Not Yet Adopted

Credit Losses. In June 2016, the FASB issued ASU 2016-13, Financial Instruments—Credit Losses (Topic 326), Measurement of Credit Losses on Financial Instruments. ASU 2016-13 requires entities to measure all expected credit losses for most financial assets held at the reporting date based on an expected loss model which includes historical experience, current conditions, and reasonable and supportable forecasts. Entities will now use forward-looking information to better form their credit loss estimates. ASU 2016-13 also requires enhanced disclosures to help financial statement users better understand significant estimates and judgments used in estimating credit losses, as well as the credit quality and underwriting standards of an entity's portfolio. Because the Company met the SEC definition of a smaller reporting company when ASU 2016-13 was issued, this new accounting standard will be effective for the Company in the first quarter of 2023. The Company is currently evaluating the impact this standard will have on its consolidated financial statements and related disclosures.

Business Combinations: Accounting for Contract Assets and Contract Liabilities from Contracts with Customers
In October 2021, the FASB issued ASU 2021-08, Business Combinations (Topic 805): Accounting for Contract Assets and Contract Liabilities from Contracts with Customers. This update requires that an acquirer recognize and measure contract assets and contract liabilities acquired in a business combination in accordance with Topic 606, Revenue from Contracts with Customers. This standard will be effective for the Company in the first quarter of 2023 and will be applied prospectively to business combinations occurring on or after the effective date of the standard. Early adoption is permitted, including adoption in an interim period. The Company is currently evaluating the guidance and the impact on its consolidated financial statements and related disclosures.






10




2. Balance Sheet Details

Allowance for Doubtful Accounts
(In thousands)Balance at Beginning of PeriodProvisionsWrite-offs, NetBalance at End of Period
Three months ended March 31, 2022$945 $20 $— $965 
Three months ended March 31, 2021$137 $17 $— $154 

Inventories
(In thousands)March 31, 2022December 31, 2021
Raw materials$27,764 $25,733 
Work-in-process6,949 6,941 
Finished goods47,583 42,396 
Inventories$82,296 $75,070 

Prepaid Expenses and Other Current Assets
(In thousands)March 31, 2022December 31, 2021
Prepayments, advances and deposits$34,444 $25,140 
Non-inventory production supplies3,762 3,956 
Recoverable taxes from Brazilian government entities1,298 1,188 
Other3,698 3,229 
Total prepaid expenses and other current assets$43,202 $33,513 

Property, Plant and Equipment, Net
(In thousands)March 31, 2022December 31, 2021
Manufacturing facilities and equipment$69,126 $51,855 
Leasehold improvements48,483 45,780 
Computers and software9,481 9,174 
Furniture and office equipment, vehicles and land3,789 3,688 
Construction in progress89,656 48,032 
220,535 158,529 
Less: accumulated depreciation and amortization(95,271)(85,694)
Property, plant and equipment, net$125,264 $72,835 

During the three months ended March 31, 2022 and 2021, depreciation and amortization expense, including amortization of right-of-use assets under financing leases, was as follows:
Three Months Ended March 31,
(In thousands)20222021
Depreciation and amortization expense$2,400 $2,114 

Goodwill

The changes in the carrying amount of goodwill were as follows:
(In thousands)
March 31, 2022
Balance at beginning of year
$131,259 
Acquisitions
7,666 
Effect of currency translation adjustment(2,920)
Ending balance
$136,005 






11




Additions to goodwill during the three months ended March 31, 2022 related to acquisitions completed during the period. See Note 7, "Acquisitions".

Intangible Assets, Net

During the three months ended March 31, 2022, the Company recorded $18.4 million of intangible assets which related to customer relationships, trademarks and trade names, branded products, and software as a result of the acquisitions completed during the period. See Note 7, "Acquisitions".

The following table summarizes the components of intangible assets (in thousands, except estimated useful life):
March 31, 2022December 31, 2021
Amounts in thousandsEstimated Useful Life
(in Years)
GrossAccumulated AmortizationNetGrossAccumulated AmortizationNet
Trademarks and trade names, and branded products10$25,704 $(953)$24,751 $11,484 $(496)$10,988 
Customer relationships
5 - 16
8,638 (474)8,164 8,197 (267)7,930 
Developed technology and software applications
5 - 12
23,003 (400)22,603 19,962 (200)19,762 
Patents17600 (24)576 600 (15)585 
Total intangible assets$57,945 $(1,851)$56,094 $40,243 $(978)$39,265 

Amortization expense for intangible assets was $0.9 million for the three months ended March 31, 2022 and is included in general and administrative expenses.

Total future amortization of intangible assets as of March 31, 2022 is as follows (in thousands):
Amounts in thousands
2022 (remainder)
$3,188 
2023
5,875 
2024
7,027 
2025
7,177 
20266,933 
Thereafter
25,894 
Total future amortization
$56,094 

Leases

Operating Leases

The Company has operating leases primarily for administrative offices, laboratory equipment and other facilities. The operating leases have remaining terms that range from 1 to 18 years, and often include one or more options to renew. These renewal terms can extend the lease term for an additional 1 to 5 years and are included in the lease term when it is reasonably certain that the Company will exercise the option. The operating leases are classified as ROU assets under operating leases on the Company's condensed consolidated balance sheets and represent the Company’s right to use the underlying asset for the lease term. The Company’s obligation to make operating lease payments is included in "Lease liabilities" and "Lease liabilities, net of current portion" on the Company's condensed consolidated balance sheets. Operating lease right-of-use assets and liabilities are recognized at commencement date based on the present value of lease payments over the lease term. The Company had $58.9 million and $32.4 million of right-of-use assets as of March 31, 2022 and December 31, 2021, respectively. Operating lease liabilities were $45.2 million and $27.5 million as of March 31, 2022 and December 31, 2021, respectively. During the three months ended March 31, 2022 and 2021, respectively, the Company recorded $3.7 million and $1.8 million of operating lease amortization that was charged to expense, of which $0.3 million and $0.2 million was recorded to cost of products sold.

Because the rate implicit in each lease is not readily determinable, the Company uses its incremental borrowing rate to determine the present value of the lease payments. The Company has certain contracts for real estate and marketing which may contain lease and non-lease components which it has elected to treat as a single lease component.







12



Information related to the Company's right-of-use assets and related lease liabilities were as follows:

Three Months Ended March 31,
20222021
Cash paid for operating lease liabilities, in thousands$3,045$1,185
Right-of-use assets obtained in exchange for new operating lease obligations, in thousands$18,759$—
Weighted-average remaining lease term8.72.7
Weighted-average discount rate19.0%18.0%

Financing Leases

The Company has financing leases primarily for laboratory equipment. Assets purchased under financing leases are included in "Right-of-use assets under financing leases, net" on the condensed consolidated balance sheets. For financing leases, the associated assets are depreciated or amortized over the shorter of the relevant useful life of each asset or the lease term. Accumulated amortization of assets under financing leases totaled $1.3 million and $6.8 million as of March 31, 2022 and December 31, 2021, respectively.

Maturities of Financing and Operating Leases

Maturities of lease liabilities as of March 31, 2022 were as follows:
Years ending December 31:
(In thousands)
Financing
Leases
Operating
Leases
Total Leases
2022 (Remaining Nine Months)$16 $10,038 $10,054 
202322 11,638 11,660 
202421 9,145 9,166 
202521 8,964 8,985 
202616 8,953 8,969 
Thereafter— 51,221 51,221 
Total lease payments96 99,959 100,055 
Less: amount representing interest(26)(54,780)(54,806)
Total lease liability$70 $45,179 $45,249 
Current lease liability$12 $8,120 $8,132 
Noncurrent lease liability58 37,059 37,117 
Total lease liability$70 $45,179 $45,249 

Other Assets

(In thousands)March 31, 2022December 31, 2021
Investment in non-trade receivable(1)
$10,049 $— 
Equity-method investments in affiliates9,654 9,443 
Deposits447 129 
Other3,384 994 
Total other assets$23,534 $10,566 
______________
(1) In March 2022, the Company loaned a privately held company $10 million in exchange for a senior secured convertible promissory note (the Note) which matures in March 2025, unless earlier redeemed or converted into equity of the privately held company. The Note bears interest at 8% per annum and is convertible, at the Company's option, into equity of the privately held company upon maturity of the Note or in the event of an initial public offering, equity financing, or corporate transaction (such as a sale or merger), in each case, at a conversion price that is dependent on a variety of factors. In addition, the Note is redeemable prior to maturity, at the issuer's option, in the event of one or more equity or debt financings, one or more asset sales, or an initial public offering, in each case equal to or greater than $50 million in the aggregate. The Company concluded that the arrangement qualifies for accounting as a loan as required by ASC 310-10. The Company will periodically evaluate the collectibility of the loan, and an allowance for credit losses will be recorded when the Company concludes that all or a portion of the loan balance is no longer collectible.






13










14



Accrued and Other Current Liabilities
(In thousands)March 31, 2022December 31, 2021
Business acquisitions contingent consideration payable(1)
$24,872 $— 
Accrued interest12,957 9,572 
Payroll and related expenses11,178 9,151 
Liability in connection with acquisition of equity-method investment9,309 8,735 
Beauty Labs deferred consideration payable(2)
5,369 30,000 
Asset retirement obligation(3)
4,145 3,336 
Professional services3,057 2,447 
Contract termination fees1,407 1,345 
Tax-related liabilities1,233 988 
License fee payable1,050 1,050 
Other5,977 4,833 
Total accrued and other current liabilities$80,554 $71,457 
______________
(1)    Business acquisitions contingent consideration payable is the current portion of total acquisition-related contingent consideration.
(2)    Approximately $23.7 million of the $30.0 million of Beauty Labs deferred consideration was settled with Amyris common stock in March 2022.
(3)    The asset retirement obligation represents liabilities incurred but not yet discharged in connection with the Company's 2013 abandonment of a partially constructed facility in Pradópolis, Brazil.







15




3. Fair Value Measurement

Liabilities Measured and Recorded at Fair Value on a Recurring Basis

The following tables summarize liabilities measured at fair value, and the respective fair value by input classification level within the fair value hierarchy:
(In thousands)March 31, 2022December 31, 2021
Level 1Level 2Level 3TotalLevel 1Level 2Level 3Total
Liabilities
Foris Convertible Note (LSA Amendment)$— $— $86,630 $86,630 $— $— $107,427 $107,427 
Freestanding derivative instruments issued in connection with debt and equity instruments— — 5,247 5,247 — — 7,062 7,062 
Total liabilities measured and recorded at fair value$— $— $91,877 $91,877 $— $— $114,489 $114,489 

The Company did not hold any financial assets to be measured and recorded at fair value on a recurring basis as of March 31, 2022 and December 31, 2021. Also, there were no transfers between the levels during the three months ended March 31, 2022 or the year ended December 31, 2021.

The Company’s assessment of the significance of a particular input to the fair value measurement in its entirety requires management to make judgements and consider factors specific to the asset or liability. The method of determining the fair value of embedded derivative liabilities is described subsequently in this note. Market risk associated with embedded derivative liabilities relates to the potential reduction in fair value and negative impact to future earnings from a decrease in interest rates.

Changes in fair value of derivative liabilities are presented as gains or losses in the condensed consolidated statements of operations in the line captioned "Gain (loss) from change in fair value of derivative instruments".

Changes in the fair value of debt that is accounted for at fair value are presented as gains or losses in the condensed consolidated statements of operations in the line captioned "Gain (loss) from change in fair value of debt".

Fair Value of Debt — Foris Convertible Note

At March 31, 2022, the contractual outstanding principal of the Foris Convertible Note was $50.0 million, and fair value was $86.6 million. The Company remeasured the fair value of the Foris Convertible Note under a binomial lattice model (which is discussed in further detail below) using the following inputs: (i) $4.36 stock price, (ii) 21% discount yield, (iii) 0.52% risk free interest rate (iv) 45% equity volatility and (v) 5% probability of change in control. The Company assumed that if a change of control event were to occur, it would occur at the end of the calendar year. For the three months ended March 31, 2022, the Company recorded a gain of $20.8 million related to change in fair value of the Foris Convertible Note. The most sensitive input to the valuation model is the Company’s stock price in relation to the $3.00 conversion price.

Binomial Lattice Model

A binomial lattice model was used to determine whether the Foris Convertible Note would be converted, called or held at each decision point. Within the lattice model, the following assumptions are made: (i) the convertible note will be converted early if the conversion value is greater than the holding value and (ii) the convertible note will be called if the holding value is greater than both (a) redemption price and (b) the conversion value at the time. If the convertible note is called, the holder will maximize their value by finding the optimal decision between (1) redeeming at the redemption price and (2) converting the convertible note. Using this lattice method, the Company valued the Foris Convertible Note using the "with-and-without method", where the fair value of the Foris Convertible Note including the embedded features is defined as the "with," and the fair value of the Foris Convertible Note excluding the embedded features is defined as the "without." This method estimates the fair value of the Foris Convertible Note by considering the incremental value of the Foris Convertible Note with the embedded features. The lattice model uses the stock price, conversion price, maturity date, risk-free interest rate, estimated stock volatility, estimated credit spread and other instrument-specific assumptions. The Company remeasures the fair value of the Foris Convertible Note and records the change as a gain or loss from change in fair value of debt in the statement of operations for each reporting period.

Derivative Liabilities Recognized in Connection with the Issuance of Debt Instruments







16



The following table provides a reconciliation of the beginning and ending balances for the Company's derivative liabilities recognized in connection with the issuance of debt instruments, either freestanding or embedded, measured at fair value using significant unobservable inputs (Level 3):
(In thousands)Derivative Liability
Balance at December 31, 2021$7,062 
Change in fair value of derivative instruments(1,815)
Derecognition on settlement or extinguishment— 
Balance at March 31, 2022$5,247 

Valuation Methodology and Approach to Measuring the Derivative Liabilities

The Company's outstanding derivative liabilities at March 31, 2022 and December 31, 2021 represent the fair value of a freestanding equity instrument. See Note 6, "Stockholders' Deficit" for further information regarding the host instrument. There is no current observable market for this type of derivative and, as such, the Company determined the fair value of the freestanding instrument using the Black-Scholes-Merton option pricing model, which is discussed in more detail below.

The Company used the Black-Scholes-Merton option pricing model to determine the fair value of its liability classified warrants as of March 31, 2022 and December 31, 2021. Input assumptions for the freestanding instrument are as follows:
Range for the Period
Input assumptions for liability classified warrants:March 31, 2022December 31, 2021
Fair value of common stock on issue date
$4.36
$5.41
Exercise price of warrants
$2.87
$2.87
Expected volatility
106%
107%
Risk-free interest rate
2.28%
0.07% – 0.28%
Expected term in years
2
2
Dividend yield0.0 %0.0 %

Changes in valuation assumptions can have a significant impact on the valuation of the freestanding derivative liabilities and debt that the Company elects to account for at fair value. For example, all other things being equal, generally, an increase in the Company’s stock price, change of control probability, risk-adjusted yields, term to maturity/conversion or stock price volatility increases the value of the derivative liability.

Acquisition related contingent consideration

The fair value of acquisition related contingent consideration (Earnout Payments) was determined using a Monte Carlo simulation to estimate the probability of the acquired business units achieving the relevant financial and operational milestones. The model results reflect the time value of money, non-performance risk within the required time frame and the risk due to uncertainty in the estimated cash flows. Key inputs to the Monte Carlo simulation for the MenoLabs acquisition were: Revenue Risk Adjustment of 6.2% and Annual Revenue Volatility of 35%. A significant decrease or increase in an acquired business unit’s financial performance and the timing of such changes could materially decrease or increase the fair value of contingent consideration period over period. Contingent consideration is recorded in other liabilities in the accompanying consolidated balance sheets.

The fair value of contingent consideration is classified as Level 3. The changes in fair value are as follows:
(In thousands)March 31, 2022
Beginning balance January 1, 2022
$64,762 
MenoLabs acquisition440 
Adjustment(79)
Change in fair value of contingent consideration
— 
Ending balance March 31, 2022
$65,123 







17



Any change in the fair value of the contingent consideration liability is recognized in general and administrative expense and reflects the changes in the business unit’s expected performance over the remaining earnout period and the Company’s estimate of the likelihood of achieving the applicable operational milestones (see Note 7, “Acquisitions”).

Assets and Liabilities Recorded at Carrying Value

Financial Assets and Liabilities

The carrying amounts of certain financial instruments, such as cash equivalents, accounts receivable, prepaid expenses and other current assets, accounts payable and other current accrued liabilities, approximate fair value due to their relatively short maturities and low market interest rates, if applicable. Loans payable and credit facilities are recorded at carrying value, which is representative of fair value at the date of acquisition. The Company estimates the fair value of these instruments using observable market-based inputs (Level 2). The carrying amount (the total amount of net debt presented on the balance sheet) of the Company's debt at March 31, 2022 and at December 31, 2021, excluding the debt instruments recorded at fair value, was $673.1 million and $310.0 million, respectively. The fair value of such debt at March 31, 2022 and at December 31, 2021 was $249.3 million and $328.0 million, respectively, and was determined by (i) discounting expected cash flows using current market discount rates estimated for certain of the debt instruments and (ii) using third-party fair value estimates for the remaining debt instruments.

4. Debt

Net carrying amounts of debt are as follows:
March 31, 2022December 31, 2021
(In thousands)PrincipalUnaccreted Debt DiscountChange in Fair ValueNetPrincipalUnaccreted Debt DiscountChange in Fair ValueNet
Convertible notes
2026 convertible senior notes$690,000 $(17,995)$— $672,005 $690,000 $(380,939)$— $309,061 
Related party convertible notes
Foris convertible note (due July 2022)50,041 — 36,589 86,630 50,041 — 57,386 107,427 
Loans payable and credit facilities
Other loans payable (revolving)1,055 — — 1,055 896 — — 896 
Total debt$741,096 $(17,995)$36,589 759,690 $740,937 $(380,939)$57,386 417,384 
Less: current portion(87,686)(108,323)
Long-term debt, net of current portion$672,004 $309,061 

Interest expense was as follows:
Three Months Ended March 31,
(In thousands)20222021
Contractual interest expense in connection with debt$3,415 $3,553 
Debt discount accretion962 713 
Interest expense in connection with debt4,377 4,266 
Financing lease interest expense165 
Discount accretion on liability in connection with acquisition of equity-method investment and with partnership liability, and other883 1,382 
Total interest expense$5,263 $5,813 

Adoption of ASU 2020-06

ASU 2020-06 became effective for the Company in the first quarter of 2022. The January 1, 2022 adoption of this standard, in connection with the 2026 Convertible Senior Notes, decreased additional paid-in capital by $368.0 million, increased debt by the same amount, and decreased the accumulated deficit by $6.0 million for debt discount accretion expense that was recorded prior to adoption.

Future Minimum Payments







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Future minimum payments under the Company's debt agreements as of March 31, 2022 are as follows:
(In thousands)Convertible NotesRelated Party Convertible NotesLoans
Payable and Credit Facilities
Total
2022 (Remaining Nine Months)$10,321 $59,578 $157 $70,056 
202310,350 — 1,129 11,479 
202410,350 — — 10,350 
202510,350 — — 10,350 
2026700,379 — — 700,379 
Thereafter— — — — 
Total future minimum payments741,750 59,578 1,286 802,614 
Less: amount representing interest(51,750)(9,537)(231)(61,518)
Present value of minimum debt payments690,000 50,041 1,055 741,096 
Less: current portion of debt principal— (50,041)— (50,041)
Noncurrent portion of debt principal$690,000 $— $1,055 $691,055 

5. Mezzanine Equity

Gates Foundation

Contingently redeemable common stock as of March 31, 2022 and December 31, 2021 is comprised of proceeds from shares of common stock sold on May 10, 2016 to the Bill & Melinda Gates Foundation (the Gates Foundation). In connection with the stock sale, the Company and the Gates Foundation entered into an agreement under which the Company agreed to expend an aggregate amount not less than the proceeds from the stock sale to develop a yeast strain that produces artemisinic acid and/or amorphadiene at a low cost and to supply such artemisinic acid and amorphadiene to companies qualified to convert artemisinic acid and amorphadiene to artemisinin for inclusion in artemisinin combination therapies used to treat malaria. If the Company defaults on its obligation to use the proceeds from the stock sale as set forth above or defaults under certain other commitments in the agreement, the Gates Foundation will have the right to request that the Company redeem, or facilitate the purchase by a third party, the shares then held by the Gates Foundation at a price per share equal to the greater of (i) the closing price of the Company’s common stock on the trading day prior to the redemption or purchase, as applicable, or (ii) an amount equal to $17.10 plus a compounded annual return of 10%. The Company concluded a redemption event was not probable to occur. As of March 31, 2022, the Company's remaining research and development obligation under this arrangement was $0.2 million.

Ingredion Contingently Redeemable Noncontrolling Interest in Subsidiary

On June 1, 2021, the Company entered into a Membership Interest Purchase Agreement (MIPA) with Ingredion Corporation (Ingredion) to purchase 31% of the member units in RealSweet LLC (RealSweet), a 100% owned Amyris, Inc. subsidiary. Total consideration was $28.5 million in the form of a $10 million cash payment, the exchange of a $4 million payable previously due to Ingredion and $14.5 million of manufacturing intellectual property rights. The terms of the MIPA provide both parties with put/call rights under certain circumstances, including the occurrence of either or both of the following: (i) a change in ownership of fifty percent (50%) or more of the voting shares of such Member; or (ii) a change in the right to appoint or remove a majority of the board of directors of such Member. The Company concluded this change in control provision was not solely within its control and Ingredion’s contingently redeemable noncontrolling interest should be reflected outside of permanent equity in accordance with SEC’s Accounting Series Release 268, Presentation in Financial Statements of Redeemable Preferred Stocks (ASR 268).

The redemption price of this common-share noncontrolling interest is considered to be at fair value on the redemption date. Ingredion’s noncontrolling interest is not currently redeemable and the Company concluded a contingent redemption event is not probable to occur. The primary redemption contingency relates to a decrease in Ingredion’s ownership percentage below 8.4%, which is not likely to occur given that capital transactions require the unanimous consent of each member. Consequently, the noncontrolling interest will not be subsequently remeasured to its redemption amount until such contingency event and the related redemption are probable to occur; however, the Company will continue to reflect the attribution of any losses and distribution of dividends to the noncontrolling interest each quarter in accordance with ASC 810-10. At the transaction date, the Company recorded the $28.5 million noncontrolling interest in RealSweet as Mezzanine equity - contingently redeemable noncontrolling interest, which represented the value of Ingredion’s 31% ownership interest in the net assets of the RealSweet subsidiary. Under the terms of the MIPA, Amyris, Inc., is funding the construction costs of the project, which are estimated to






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be approximately $115 million. As of March 31, 2022, the Company has funded approximately $68 million towards the project and has $38 million of contractual purchase commitments for construction related costs.

EcoFabulous Contingently Redeemable Noncontrolling Interest in Subsidiary

On January 26, 2022, the Company and certain of its subsidiaries entered into an Agreement and Plan of Merger for the acquisition of 70% of No Planet B LLC (d/b/a EcoFabulous), a privately held company. In connection with the merger, the name of No Planet B LLC has been changed to EcoFab, LLC (EcoFab). No Planet B Investments, LLC holds 30% of the outstanding units of membership interests in EcoFab as of the effective time of the merger (the Minority Member). See Note 7, "Acquisitions". Concurrently, the Company and No Planet B Investments, LLC entered into the EcoFab, LLC Agreement, the terms of which provide the Minority Member a right to require EcoFab to repurchase its 30% noncontrolling interest after (i) EcoFab achieving Net Revenues in excess of $100 million on an annualized basis or, if earlier, (ii) December 31, 2026. The Company concluded this provision was not solely within its control and EcoFab’s contingently redeemable noncontrolling interest should be reflected outside of permanent equity in accordance with SEC’s Accounting Series Release 268, Presentation in Financial Statements of Redeemable Preferred Stocks (ASR 268) and ASC 480-10-S99, “Distinguishing Liabilities from Equity” (ASC 480).

The redemption price of this noncontrolling interest is considered to be at fair value on the redemption date. EcoFab’s noncontrolling interest is not currently redeemable and the Company concluded a contingent redemption event is probable to occur as the redemption date is no later than December 31, 2026. As a result, the noncontrolling interest will be recorded at the higher of (1) the cumulative amount that would result from applying the measurement guidance in ASC 810-10 (i.e., initial carrying amount, increased or decreased for the noncontrolling interest’s share of net income or loss, OCI or other comprehensive loss, and dividends) or (2) the redemption price. When it is determined the redemption price exceeds the noncontrolling interest’s carrying amount, the Company will record an ASC 480 measurement adjustment. As of March 31, 2022, the Company recorded $2.9 million EcoFab noncontrolling interest as Mezzanine equity - contingently redeemable noncontrolling interest, which included $3.1 million of the initial value of the Minority Member’s 30% ownership interest in the net assets of EcoFab and $0.2 million of losses attributable to the Minority Member during the period.

6. Stockholders' (Deficit) Equity

Warrants and Rights Activity Summary

In connection with various debt and equity transactions (see Note 4, “Debt” above, and Note 4, "Debt" and Note 6, “Stockholders’ Deficit” in Part II, Item 8 of the 2021 Form 10-K), the Company has issued warrants exercisable for shares of common stock. The following table summarizes warrants outstanding at March 31, 2022:
TransactionYear IssuedExpiration DateNumber Outstanding as of December 31, 2021ExercisesExpiredExercise Price per Share of Warrants ExercisedNumber Outstanding as of March 31, 2022Exercise Price per Share as of March 31, 2022
Blackwell / Silverback warrants 2020 July 10, 20221,000,000 — — 1,000,000 $3.25 
January 2020 warrant exercise right shares 2020 January 31, 2022431,378 (431,378)— $2.87 — $— 
May 2019 6.50% Note Exchange warrants 2019 January 31, 2022960,225 (960,225)— $2.87 — $— 
May 2017 cash warrants 2017 July 10, 20221,492,652 — 1,492,652 $2.87 
May 2017 dilution warrants 2017 July 10, 202256,910 — — 56,910 $— 
July 2015 related party debt exchange 2015 July 29, 202558,690 — — 58,690 $0.15 
3,999,855 (1,391,603)— $2.87 2,608,252 

Warrant Exercises

During the three months ended March 31, 2022, warrant-holders exercised warrants to purchase 1,391,603 shares of the Company’s common stock at a weighted-average exercise price of $2.87 per share, for proceeds to the Company of $4.0 million.






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7. Acquisitions

The purchase accounting for the net assets acquired, including goodwill, and the fair value of the contingent consideration and noncontrolling interest for the following acquisitions is preliminarily recorded based on available information and incorporates management's best estimates. The purchase accounting for taxes remains preliminary pending receipt of certain information required to finalize the determination of fair value. The net assets acquired in the transaction are generally recorded at their estimated acquisition-date fair values, while transaction costs associated with the acquisition are expensed as incurred. These transactions were accounted for by the acquisition method, and accordingly, the results of operations were included in the Company’s consolidated financial statements from their respective acquisition dates. Pro forma financial information is not presented as amounts are not material to the Company’s consolidated financial statements.

EcoFab LLC.

On January 26, 2022, the Company and certain of its subsidiaries entered into an Agreement and Plan of Merger for the acquisition of 70% of No Planet B LLC (d/b/a EcoFabulous), a privately held company. EcoFabulous is focused on delivering high performance, makeup artist-quality clean beauty products in ecofriendly packaging, and priced for Gen Z consumers. In connection with the merger, the name of No Planet B LLC has been changed to EcoFab, LLC (EcoFab). No Planet B Investments, LLC holds 30% of the outstanding units of membership interests in EcoFab as of the effective time of the merger, which is accounted for as Mezzanine equity - contingently redeemable noncontrolling interest. See Note 5, "Mezzanine Equity".

The purchase consideration for the acquisition of EcoFab consisted of $1.7 million in cash and 1,292,776 shares of Amyris stock with a fair value of $5.5 million. The noncontrolling interest had a fair value of $3.1 million as of the acquisition date.

The following table summarizes the purchase price allocation:
(In thousands)
Trademarks, trade names and other intellectual property
$8,705 
Customer relationships
512 
Goodwill
1,023 
Less: noncontrolling interest$(3,072)
Total consideration
$7,168 

Goodwill associated with this acquisition is expected to be deductible for tax purposes.

The Company has determined that (i) EcoFab is a variable-interest entity (VIE) due to insufficient equity at risk, (ii) the Company is the primary beneficiary of EcoFab due to its power to direct the activities that most significantly affect EcoFab’s economic performance, and (iii) the Company has the ability to exert significant influence over EcoFab through its 70% equity ownership. As a result, the Company accounts for its investment in EcoFab on a consolidation basis in accordance with ASC 810, Consolidation.

MenoLabs, LLC.

On March 9, 2022, Amyris and Amyris Clean Beauty, Inc., a wholly owned subsidiary of Amyris, entered into an Asset Purchase Agreement with MenoLabs, LLC, (MenoLabs), an Arizona limited liability company, to purchase substantially all of the assets and assume the liabilities of MenoLabs. The transaction closed on March 10, 2022 (the Closing Date). MenoLabs was founded to fundamentally change how menopause is addressed by offering research-backed all-natural treatments of menopause symptoms. Prior to the Closing Date, Amyris and MenoLabs entered into that certain Loan Agreement and Promissory Note in January 2022, pursuant to which Amyris loaned to MenoLabs the aggregate principal amount of $0.5 million. In connection with the acquisition of MenoLabs, Amyris has assumed the Bridge Loan. The acquisition of MenoLabs will serve as a catalyst to accelerate growth and establish a leadership position in the fast-growing menopause market.

MenoLabs was acquired for total purchase consideration of $16.2 million, consisting of $11.3 million in cash, the Bridge Loan of $0.5 million, 852,234 shares of Amyris stock with a fair value of $3.9 million, and contingent consideration with a fair value of $0.4 million. The contingent consideration consists of two potential payments of up to $10 million each during the twelve (12) month period beginning on the first day of the first calendar month commencing after the Closing Date and the fourth quarter of 2024 respectively if both MenoLabs’s product revenues and profit margin meet the targets set forth for such period in the Asset Purchase Agreement (the Earnout Payments). The Earnout Payments will be in the form of cash or in an aggregate number of shares of Amyris Stock equal to the earnout achieved divided by the stock price on achievement date, at Amyris’s sole discretion. The $0.4 million fair value of the Earnout Payments is recorded as other liabilities in the accompanying condensed consolidated balance sheets. Allocation of the contingent consideration payments between short-term






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and long-term liabilities on the accompanying consolidated balance sheets is based on management’s best estimates of when the relevant milestone will be achieved.

The following table summarizes the purchase price allocation:
(In thousands)
Net tangible assets
$311 
Branded products
5,600 
Application (App)
3,600 
Goodwill
6,642 
Total consideration
$16,153 

Goodwill associated with this acquisition is expected to be deductible for tax purposes.






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8. Net Loss per Share Attributable to Common Stockholders

The Company follows the two-class method when computing net loss per common share when shares are issued that meet the definition of participating securities. The two-class method requires income available to common stockholders for the period to be allocated between common stock and participating securities based upon their respective rights to receive dividends as if all income for the period had been distributed. The two-class method also requires losses for the period to be allocated between common stock and participating securities based on their respective rights if the participating security contractually participates in losses. The Company’s convertible preferred stock are participating securities as they contractually entitle the holders of such shares to participate in dividends and contractually require the holders of such shares to participate in the Company’s losses.

The following table presents the calculation of basic and diluted loss per share:

Three Months Ended March 31,
(In thousands, except shares and per share amounts)20222021
Numerator:
Net loss attributable to Amyris, Inc.$(107,305)$(291,251)
Less: loss allocated to participating securities— 2,099 
Net loss attributable to Amyris, Inc. common stockholders, basic$(107,305)$(289,152)
Interest on convertible debt457 — 
Gain from change in fair value of debt(12,650)— 
Gain from change in fair value of derivative instruments(1,815)— 
Net loss attributable to Amyris, Inc. common stockholders, diluted$(121,313)$(289,152)
Denominator:
Weighted-average shares of common stock outstanding used in computing net loss per share of common stock, basic312,896,452 267,733,555 
Net loss per share, basic$(0.34)$(1.08)
Weighted-average shares of common stock outstanding312,896,452 267,733,555 
Effect of dilutive convertible debt10,146,017 — 
Effect of dilutive common stock warrants669,213 — 
Weighted-average shares of common stock equivalents used in computing net loss per share of common stock, diluted323,711,682 267,733,555 
Net loss per share, diluted$(0.37)$(1.08)

For the three months ended March 31, 2022 and 2021, basic income per share differed from diluted loss per share, because the inclusion of all potentially dilutive securities outstanding was dilutive. The following table presents outstanding shares of potentially dilutive securities:
Three Months Ended March 31,
20222021
Period-end common stock warrants2,492,65213,416,235
Convertible promissory notes(1)
86,683,38919,540,447
Period-end stock options to purchase common stock3,800,3146,205,576
Period-end restricted stock units17,305,3376,653,640
Contingently issuable common shares1,718,475
Period-end preferred stock1,943,661
Total potentially dilutive securities excluded from computation of diluted loss per share112,000,16747,759,559
______________
(1)    The potentially dilutive effect of convertible promissory notes was computed based on conversion ratios in effect as of the respective period end dates. A portion of the convertible promissory notes issued carries a provision for a reduction in conversion price under certain circumstances, which could potentially increase the dilutive shares outstanding. Another portion of the convertible promissory notes issued carries a provision for an increase in the conversion rate under certain circumstances, which could also potentially increase the dilutive shares outstanding.

9. Commitments and Contingencies

Guarantor Arrangements






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The Company has agreements whereby it indemnifies its executive officers and directors for certain events or occurrences while the executive officer or director is serving in his or her official capacity. The indemnification period remains enforceable for the executive officer's or director’s lifetime. The maximum potential amount of future payments the Company could be required to make under these indemnification agreements is unlimited; however, the Company has a director and officer insurance policy that limits its exposure and enables the Company to recover a portion of any future payments. As a result of its insurance policy coverage, the Company believes the estimated fair value of these indemnification agreements is minimal. Accordingly, the Company had no liabilities recorded for these agreements as of March 31, 2022 and December 31, 2021.

The Foris Convertible Note (see Note 4, "Debt") is collateralized by first-priority liens on substantially all of the Company's assets, including Company intellectual property, other than certain Company intellectual property licensed to DSM, the Company's international subsidiaries and the Company’s ownership interests in joint ventures. Certain of the Company’s subsidiaries have guaranteed the Company’s obligations under the Foris Convertible Note.

In October 2021, the Company entered into a 10-year manufacturing partnership agreement with Renfield Manufacturing, LLC (Renfield) to provide manufacturing services and third-party logistics processes, including inventory management, warehousing, and fulfillment for certain of the Company’s consumer product lines. The Company also provided a $0.5 million letter of credit and guarantee to the lessor of the Renfield manufacturing facility, which extends through August 2032. If Renfield fails to perform under the facility lease, the Company can terminate the manufacturing agreement. The Company expects that its potential future performance under the guarantee is not probable of occurrence. Accordingly, the Company had no liabilities recorded for the guarantee as of March 31, 2022 and December 31, 2021.

Other Matters

Certain conditions may exist as of the date the financial statements are issued, which may result in a loss to the Company but will only be recorded when one or more future events occur or fail to occur. The Company's management assesses such contingent liabilities, and such assessment inherently involves an exercise of judgement. In assessing loss contingencies related to legal proceedings that are pending against and by the Company or unasserted claims that may result in such proceedings, the Company's management evaluates the perceived merits of any legal proceedings or unasserted claims as well as the perceived merits of the amount of relief sought or expected to be sought.

If the assessment of a contingency indicates that it is probable that a material loss has been incurred and the amount of the liability can be estimated, then the estimated liability would be accrued in the Company's financial statements. If the assessment indicates that a potential material loss contingency is not probable but is reasonably possible, or is probable but cannot be reasonably estimated, then the nature of the contingent liability, together with an estimate of the range of possible loss if determinable and material, would be disclosed. Loss contingencies considered to be remote by management are generally not disclosed unless they involve guarantees, in which case the guarantee would be disclosed.

On April 3, 2019, a securities class action complaint was filed against Amyris and our CEO, John G. Melo, and former CFO, Kathleen Valiasek, in the U.S. District Court for the Northern District of California. The complaint seeks unspecified damages on behalf of a purported class that would comprise all persons and entities that purchased or otherwise acquired our securities between March 15, 2018 and March 19, 2019. The complaint, which was amended by the lead plaintiff on September 13, 2019, alleges securities law violations based on statements and omissions made by the Company during such period. On October 25, 2019, the defendants filed a motion to dismiss the securities class action complaint, which was denied by the court on October 5, 2020. The Company filed its answer to the securities class action complaint on October 26, 2020. In early 2021, the parties attended court-ordered mediation, but as the case did not settle, the parties commenced discovery. On July 30, 2021, plaintiffs filed a motion seeking class certification and the Company filed its opposition on September 24, 2021; after briefing and argument, it was granted in part on December 8, 2021. On December 22, 2021, the Company filed a petition seeking interlocutory review of that order in the U.S. Court of Appeals for the Ninth Circuit, which was fully briefed on January 14, 2022. On February 4, 2022, the parties reached a tentative settlement of the securities class action, which requires the court’s review and approval. On March 24, 2022, the parties submitted the proposed settlement agreement to the Court. If the settlement is approved by the Court, the settlement amount will be covered by the Company’s directors and officers insurance policy.

Subsequent to the filing of the securities class action complaint described above, on June 21, 2019 and October 1, 2019, respectively, two separate purported shareholder derivative complaints were filed in the U.S. District Court for the Northern District of California (Bonner v. Doerr, et al., and Carlson v. Doerr, et al.) based on similar allegations to those made in the






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securities class action complaint and naming the Company, and certain of the Company’s current and former officers and directors, as defendants. The derivative lawsuits sought to recover, on the Company’s behalf, unspecified damages purportedly sustained by the Company in connection with allegedly misleading statements and omissions made in connection with the Company’s securities filings. The derivative lawsuits were dismissed on October 18, 2019 (Bonner) and December 10, 2019 (Carlson), without prejudice. On November 3, 2020, Bonner re-filed its derivative complaint against the Company in San Mateo County Superior Court. The Company filed its demurrer to the complaint on January 13, 2021 and attended a preliminary hearing on April 22, 2021. An additional shareholder derivative complaint (Kimbrough v. Melo, et al.), substantially identical to the Bonner complaint, was filed on December 18, 2020 in the United States District Court for the Northern District of California. On February 19, 2021, the Company filed its motion to dismiss the Kimbrough complaint. In response, the Kimbrough complaint was dismissed in federal court on March 4, 2021 and refiled in state court on March 12, 2021. By agreement, the Kimbrough and Bonner complaints were consolidated for all purposes on April 9, 2021. The motion to dismiss was granted without prejudice on June 30, 2021. After obtaining an extension, Bonner amended his complaint on February 22, 2022. On March 24, 2022, the Company filed a motion seeking full dismissal with prejudice of claims alleged in Bonner’s amended complaint. An oral argument on the Company's motion to dismiss is scheduled for June 9, 2022. The Company believes the amended complaint lacks merit, and intends to continue to defend itself vigorously. Given the early stage of these proceedings, it is not yet possible to reliably determine any potential liability that could result from these matters.

On September 10, 2020, LAVVAN, Inc. (Lavvan) filed a suit against the Company in the United States District Court for the Southern District of New York alleging breach of contract, patent infringement, and trade secret misappropriation in connection with that certain Research, Collaboration and License Agreement between Lavvan and Amyris, dated March 18, 2019, as amended (Cannabinoid Agreement). The Company filed motions to compel arbitration or to dismiss on October 2, 2020. On October 30, Lavvan filed its opposition to the motions and the Company filed its reply to such opposition on November 13, 2020. The Court denied the Company's motions on July 26, 2021, and the Company appealed the Court's ruling regarding its motion to compel arbitration on July 27, 2021 and filed its appeal to the U.S. Court of Appeals for the Second Circuit on November 4, 2021. While the appellate briefing process was completed on January 19, 2022, the Court has not yet scheduled oral argument. The Company believes the suit lacks merit and intends to continue to defend itself vigorously. Given the early stage of these proceedings, it is not yet possible to reliably determine any potential liability that could result therefrom.

The Company is subject to disputes and claims that arise or have arisen in the ordinary course of business and that have not resulted in legal proceedings or have not been fully adjudicated. Such matters that may arise in the ordinary course of business are subject to many uncertainties and outcomes, and are not predictable with reasonable assurance; therefore, an estimate of all the reasonably possible losses cannot be determined at this time. If one or more of these legal disputes or claims resulted in settlements or legal proceedings that were resolved against the Company for amounts in excess of management’s expectations, the Company’s condensed consolidated financial statements for the relevant reporting period could be materially adversely affected.

10. Revenue Recognition, and Contract Assets and Liabilities

Disaggregation of Revenue

The following table presents revenue by major product and service, as well as by primary geographical market, based on the location of the customer:
Three Months Ended March 31,
(In thousands)20222021
Renewable ProductsLicenses and RoyaltiesCollaborations, Grants and OtherTotalRenewable ProductsLicenses and RoyaltiesCollaborations, Grants and OtherTotal
North America$32,956 $433 $1,476 $34,865 $20,090 $— $250 $20,340 
Europe7,289 8,880 3,263 19,432 2,972 143,800 2,346 149,118 
Asia1,488 — 192 1,680 4,405 — 2,284 6,689 
South America1,019 — — 1,019 313 — — 313 
Other713 — — 713 399 — — 399 
$43,465 $9,313 $4,931 $57,709 $28,179 $143,800 $4,880 $176,859 

The following table presents revenue by major product and service, as well as by management classification:






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Three Months Ended March 31,
(In thousands)20222021
Renewable ProductsLicenses and RoyaltiesGrants, Collaborations and OtherTotalRenewable ProductsLicenses and RoyaltiesGrants, Collaborations and OtherTotal
Consumer$32,642 $433 $1,476 $34,551 $15,653 $— $— $15,653 
Technology access10,823 8,880 3,455 23,158 12,526 143,800 4,880 161,206 
$43,465 $9,313 $4,931 $57,709 $28,179 $143,800 $4,880 $176,859 

Significant Revenue Agreements and Customers

In connection with the significant revenue agreements discussed below and others previously disclosed (see Note 10, “Revenue Recognition” in Part II, Item 8 of the 2021 Form 10-K), the Company recognized the following revenue:
Three Months Ended March 31,
(In thousands)20222021
Renewable ProductsLicenses and RoyaltiesCollaborations, Grants and OtherTotalRenewable ProductsLicenses and RoyaltiesCollaborations, Grants and OtherTotal
DSM - related party$4,412 $8,816 $2,000 $15,228 $1,662 $143,612 $2,000 $147,274 
Sephora7,633 — — 7,633 4,441 — — 4,441 
PureCircle1,551 — — 1,551 — — — — 
Subtotal revenue from significant revenue agreements13,596 8,816 2,000 24,412 6,103 143,612 2,000 151,715 
Revenue from all other customers29,869 497 2,931 33,297 22,076 188 2,880 25,144 
Total revenue from all customers$43,465 $9,313 $4,931 $57,709 $28,179 $143,800 $4,880 $176,859 

DSM Ingredients Collaboration

Pursuant to the September 2017 research and development collaboration agreement, as amended, the Company provides DSM with research and development services for specific field of use ingredients. The Company concluded the amended agreement contained a single performance obligation to provide research and development services delivered over time and that revenue recognition is based on an input measure of progress as labor hours are expended each quarter. DSM funds the development work with payments of $2.0 million quarterly from January 1, 2022 to June 30, 2022 for services focused on achieving certain fermentation yield and cost targets related to certain molecules. During the three months ended March 31, 2022, the Company recognized $2.0 million of collaboration revenue in connection with the agreement.

DSM License Agreement and Contract Assignment

In March 2021 the Company and DSM entered into a license agreement and asset purchase agreement pursuant to which DSM acquired exclusive rights to the Company’s Flavor and Fragrance (F&F) product portfolio. The Company granted DSM exclusive licenses covering specific intellectual property of the Company and assigned the Company’s rights and obligations under certain F&F ingredients supply agreements to DSM, in exchange for non-refundable upfront consideration totaling $150 million, and up to $235 million of contingent consideration if and when certain commercial milestones are achieved in each of the calendar years 2022 through 2024. The Company determined the licenses to be functional intellectual property and allocated $143.6 million of the transaction price to the licenses and recorded $143.6 million of licenses and royalties revenues in the three-months ended March 31, 2021. The Company also concluded the additional contingent consideration represents variable consideration that is subject to a sales/usage-based threshold and is dependent up on the IP License. The Company is required to apply the royalty recognition constrain guidance in ASC 606-10-55-65 and will recognize revenue at the later of (1) when the underlying sales or usage has occurred and (2) the related performance obligation has been satisfied (or partially satisfied). The Company recorded $8.8 million of license and royalties revenue and a corresponding contract asset under the contingent consideration provisions of the agreements during the three-months ended March 31, 2022.

Contract Assets and Liabilities

When a contract results in revenue being recognized in excess of the amount the Company has invoiced or has the right to invoice to the customer, a contract asset is recognized. Contract assets are transferred to accounts receivable, net when the rights to the consideration become unconditional.







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Contract liabilities consist of payments received from customers, or such consideration that is contractually due, in advance of providing the product or performing services such that control has not passed to the customer.

Trade receivables related to revenue from contracts with customers are included in accounts receivable on the condensed consolidated balance sheets, net of the allowance for doubtful accounts. Trade receivables are recorded for the sale of goods or the performance of services at the point of renewable product sale or in accordance with the contractual payment terms for licenses and royalties, and grants and collaborative research and development services for the amount payable by the customer to the Company.

Contract Balances

The following table provides information about accounts receivable, contract assets and contract liabilities from contracts with customers:
(In thousands)March 31, 2022December 31, 2021
Accounts receivable, net$37,400 $37,074 
Accounts receivable - related party, net$7,279 $5,667 
Contract assets$3,883 $4,227 
Contract assets - related party$8,816 $— 
Contract liabilities$1,554 $2,530 
Contract liabilities, noncurrent(1)
$— $111 

(1)As of March 31, 2022 and December 31, 2021, contract liabilities, noncurrent is presented in Other noncurrent liabilities in the condensed consolidated balance sheets.

Remaining Performance Obligations

The following table provides information regarding the estimated revenue expected to be recognized in the future related to performance obligations that are unsatisfied (or partially unsatisfied) based on the Company's existing agreements with customers as of March 31, 2022.
(In thousands)As of March 31, 2022
Remaining 2022$718 
2023143 
2024143 
2025143 
2026 and thereafter143 
Total from all customers$1,290 

In accordance with the disclosure provisions of ASC 606, the table above excludes estimated future revenues for performance obligations that are part of a contract that has an original expected duration of one year or less or a performance obligation with variable consideration that is recognized using the sales-based royalty exception for licenses of intellectual property.

11. Related Party Transactions

Related Party Debt

Related party debt was as follows:
March 31, 2022December 31, 2021
In thousandsPrincipalUnaccreted Debt DiscountChange in Fair ValueNetPrincipalUnaccreted Debt DiscountChange in Fair ValueNet
Foris convertible note (due July 2022)$50,041 $— $36,589 $86,630 $50,041 $— $57,386 $107,427 






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Related Party Equity

There we no related party equity transactions during the three months ended March 31, 2022.

Related Party Accounts Receivable, Unbilled Receivables and Accounts Payable

Related party accounts receivable, contract assets and accounts payable were as follows:
(In thousands)March 31, 2022December 31, 2021
Accounts receivable - related party$7,279 $5,667 
Accounts payable - related party$4,945 $5,011 

12. Stock-based Compensation

The Company’s stock option activity and related information for the three months ended March 31, 2022 was as follows:
Quantity of Stock OptionsWeighted-
average
Exercise
Price
Weighted-average
Remaining
Contractual
Life, in Years
Aggregate
Intrinsic
Value, in Thousands
Outstanding - December 31, 20213,087,225 $9.91 7.1$2,580 
Granted852,667 $3.95 
Exercised(34,541)$2.83 
Forfeited or expired(105,037)$6.75 
Outstanding - March 31, 20223,800,314 $8.73 7.6$1,155 
Vested or expected to vest after March 31, 20223,800,314 $8.73 7.6$1,155 
Exercisable at March 31, 20221,648,914 $11.52 5.7$461 

Activity related to the Company’s restricted stock units (RSUs) (including performance-based restricted stock units (PSUs)) for the three months ended March 31, 2022 was as follows:
Quantity of Restricted Stock UnitsWeighted-average Grant-date Fair ValueWeighted-average Remaining Contractual Life, in Years
Outstanding - December 31, 202113,731,320 $9.99 2.8
Awarded4,423,978 $3.98 
Released(545,114)$6.25 
Forfeited(304,847)$7.41 
Outstanding - March 31, 202217,305,337 $8.62 2.5
Vested or expected to vest after March 31, 202217,305,337 $8.62 2.5

Stock-based compensation expense during the three months ended March 31, 2022 and 2021 is reflected in the condensed consolidated statements of operations as follows:
Three Months Ended March 31,
(In thousands)20222021
Cost of products sold$78 $63 
Research and development1,617 1,062 
Sales, general and administrative9,893 3,156 
Total stock-based compensation expense$11,588 $4,281 

As of March 31, 2022, $130.2 million of unrecognized compensation expense related to stock options and RSUs is expected to be recognized over a weighted-average period of 3.3 years.






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13. Subsequent Events

None.






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ITEM 2. MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS

The following discussion and analysis should be read in conjunction with our condensed consolidated financial statements and the related notes that appear elsewhere in this Quarterly Report on Form 10-Q. These discussions contain forward-looking statements reflecting our current expectations that involve risks and uncertainties which are subject to safe harbors under the Securities Act of 1933, as amended (the Securities Act), and the Securities Exchange Act of 1934 (the Exchange Act). These forward-looking statements include, but are not limited to, statements concerning our strategy of achieving a significant reduction in net cash outflows during the remainder of 2022 and 2023, aspects of our future operations, our future financial position, expectations for our future revenues, margins and projected costs, expectations regarding demand and acceptance for our technologies and products, introductions of new products, growth opportunities and trends in the market in which we operate, prospects and plans and objectives of management. The words “anticipates,” “believes,” “estimates,” “expects,” “intends,” “may,” “plans,” “projects,” “will,” “would” and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. We may not actually achieve the plans, intentions or expectations disclosed in our forward-looking statements, and you should not place undue reliance on our forward-looking statements. These forward-looking statements involve risks and uncertainties that could cause our actual results to differ materially from those in the forward-looking statements, including, without limitation, the risks set forth in Part II, Item 1A, “Risk Factors” in this Quarterly Report on Form 10-Q, in Part I, Item 1A, “Risk Factors” in our Annual Report on Form 10-K for the fiscal year ended December 31, 2021 (the 2021 Form 10-K) and in our other filings with the Securities and Exchange Commission. We do not assume any obligation to update any forward-looking statements.

Overview

We are a biotechnology company at the forefront of delivering sustainable solutions that are better for people and the planet. To accelerate the world’s transition to sustainable consumption, we create, manufacture and commercialize consumer products and ingredients that reach more than 300 million consumers. Currently, the largest driver of our revenue is derived from marketing and selling Clean Beauty, Personal Care and Health & Wellness consumer products through our direct-to-consumer ecommerce platforms and a growing network of retail partners. We also sell sustainable ingredients to sector leaders that serve Flavor & Fragrance (F&F), Nutrition, Food & Beverage, and Clean Beauty & Personal Care end markets.

We began 2021 with three consumer brands, Biossance® clean beauty skincare, Pipette® clean baby skincare, and PurecaneTM zero-calorie sweetener. During the second half of 2021, we launched five additional consumer brands in the Clean Beauty & Personal Care end market, including Terasana® clean skincare, Costa Brazil® luxury skincare, OLIKATM clean wellness, Rose Inc.TM clean color cosmetics, and JVNTM clean haircare.

Our ingredients and consumer products are powered by our fermentation-based Lab-to-MarketTM technology platform. This technology platform drives the portfolio connection between our proprietary science and formulation expertise, our manufacturing capability at industrial scale, and our ability to commercialize sustainable products that make a difference in people’s lives. We believe that our technology platform offers advantages to traditional methods of sourcing similar ingredients (such as petrochemistry and extraction from organisms). Our technology platform allows for renewable and ethical sourcing of raw materials, less resource-intensive production, minimal impact on sensitive ecosystems, enhanced purity and safety profile, less vulnerability to climate disruption, and improved supply chain resilience. We bring together biology and engineering to generate more sustainable materials that would otherwise be scarce or endangered in nature. Our technology platform leverages state-of-the-art machine learning, robotics and artificial intelligence, enabling us to rapidly bring new innovation to market. Our revenue is generated from consumer product sales, ingredient product sales, research and development collaboration programs and grants, and consumer marketing services.

Our time from lab to market for molecules has decreased from three to four years to less than a year for our most recent molecule, mainly due to our ability to leverage our technology platform with proprietary strain construction, screening and analytics tools, advanced lab automation, and data integration. Our state-of-the-art infrastructure includes industry-leading strain engineering and lab automation located in Emeryville, California, pilot-scale production facilities in Emeryville and Campinas, Brazil, a demonstration-scale facility in Campinas and a commercial scale production facility in Leland, North Carolina (which is part of our Aprinnova joint venture). While a wide variety of feedstocks for production exists, we source Brazilian sugarcane for our large-scale production because of its supply resilience, renewability, low cost, and relative price stability. We are in the process of constructing a new purpose-built, large-scale specialty ingredients facility in Brazil, which we anticipate will allow for the manufacture of up to five products concurrently. We expect construction to be completed in the






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first half of 2022. Pending commissioning of the new facility, we continue to manufacture our products at manufacturing sites in Brazil, the United States and Europe.

Sales and Revenue

We recognize revenue from consumer and ingredient product sales, license fees and royalties, and collaborations and grants.

We have research and development collaboration arrangements for which we receive payments from our collaboration partners, which include Koninklijke DSM N.V. (DSM), Firmenich SA (Firmenich), Yifan Pharmaceutical Co. Ltd. (Yifan) and others. Some of our collaboration arrangements provide for advance payments to us in consideration for grants of exclusivity or research efforts that we will perform. Our collaboration agreements, which may require us to achieve milestones prior to receiving payments, are expected to contribute revenues from product sales and royalties if and when they are commercialized. See Note 10, “Revenue Recognition” in Part II, Item 8 of our 2021 Form 10-K for additional information.

We have several other collaboration molecules in our development pipeline with partners including DSM, Givaudan, Firmenich and Yifan that we expect will contribute revenues from product sales and royalties if and when they are commercialized.

COVID-19 Business Update

We closely monitor the impact of the global COVID-19 pandemic on all aspects of our business, including how it has and will impact our employees, partners, supply chain, and distribution network. Since the start of the pandemic in early 2020, we developed a comprehensive response strategy including establishing a cross-functional COVID-19 task force and implementing business continuity plans to manage the impact of the COVID-19 pandemic on our employees and our business. We have applied recommended public health strategies designed to prevent the spread of COVID-19 and have been focused on the health and welfare of our employees. We have successfully managed to sustain ongoing critical production campaigns and infrastructure while staying in compliance with State and County public health orders.

Accordingly, since the end of the first quarter of 2020, we have initiated several precautions in accordance with local regulations and guidelines to mitigate the spread of COVID-19 infection across our businesses, which has impacted the way we carry out our business, including additional sanitation and cleaning procedures in our laboratories and other facilities, on-site COVID-19 testing, temperature and symptom confirmations, instituting remote working when possible. Our plans to reopen our sites and enable a broad return to work in our offices, laboratories and production facilities will continue to follow local public health plans and guidelines. As the effects of the COVID-19 pandemic and the availability of vaccines continue to evolve, even if our employees more broadly return to work in our offices, laboratories and production facilities, we have the flexibility to resume more restrictive on-site and remote work models, if needed, as a result of spikes or surges in COVID-19 infection, hospitalization rates or otherwise. See “Risk Factors – Business and Operational Risks - Our business is currently adversely affected and could be materially adversely affected in the future by the evolving effects of the COVID-19 pandemic and related global economic slowdown as a result of the recent and potential future impacts on our supply chain, manufacturing and commercialization activities and other business operations" in our 2021 Form 10-K.

The global business challenges associated with the COVID-19 pandemic have been recently compounded by the escalating conflict in Ukraine, which has caused significant instability and disruptions in the capital and credit markets. A severe or prolonged economic downturn could result in a variety of risks to our business, including weakened demand for our products and in our ability to raise additional capital when needed on acceptable terms, if at all. A weak or declining economy could also strain our collaboration partners and our suppliers, possibly resulting in development or supply disruption. We cannot anticipate all the ways in which the foregoing, and the current economic climate and financial market conditions generally, could adversely impact our business.

Critical Accounting Policies and Estimates

Management's discussion and analysis of results of operations and financial condition are based on our consolidated financial statements, which have been prepared in accordance with accounting principles generally accepted in the U.S. (U.S. GAAP). We believe that the critical accounting policies described in this section are those that significantly impact our financial condition and results of operations and require the most difficult, subjective or complex judgements, often as a result of the need to make estimates about the effects of matters that are inherently uncertain. Because of this uncertainty, actual results may vary from these estimates.






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Our most critical accounting estimates include:
Recognition of revenue including arrangements with multiple performance obligations;
Valuation and allocation of fair value to various elements of complex related party transactions;
The valuation of freestanding and embedded derivatives, which impacts gains or losses on such derivatives, the carrying value of debt, interest expense and deemed dividends;
The valuation of debt for which we have elected fair value accounting; and
The valuation of goodwill, intangible assets and contingent consideration payables, which are generated through business acquisitions.

For a more detailed discussion of our critical accounting estimates and policies, see Note 1, "Basis of Presentation and Summary of Significant Accounting Policies" in Part II, Item 8 of our 2021 Form 10-K and Note 1, "Basis of Presentation and Summary of Significant Accounting Policies" in Part I, Item 1 of this Quarterly Report on Form 10-Q.

Recently Issued Accounting Pronouncements

Refer to Note 1, "Basis of Presentation and Summary of Significant Accounting Policies" in Part I, Item 1 of this Quarterly Report on Form 10-Q.

Accounting Pronouncements Issued but Not Yet Adopted

Refer to Note 1, "Basis of Presentation and Summary of Significant Accounting Policies" in Part I, Item 1 of this Quarterly Report on Form 10-Q.

Results of Operations

Revenue
Three Months Ended March 31,
(In thousands)20222021
Revenue
Renewable products$43,465 $28,179 
Licenses and royalties9,313 143,800 
Collaborations, grants and other4,931 4,880 
Total revenue$57,709 $176,859 

Three months ended March 31, 2022

Total revenue decreased by 67% to $57.7 million for the three months ended March 31, 2022 compared to the same period in 2021. The decrease was mainly due to a $134.5 million decrease in license revenue. Excluding the first quarter 2021 license transaction, total revenue increased by $24.5 million. This increase was driven by an $18.9 million increase in consumer products revenue and a $9.1 million increase in royalties revenue, partially offset by a $1.7 million decrease in ingredients products revenue and a $1.4 million decrease in research and development collaboration revenue.

Renewable products revenue increased by 54% to $43.5 million for the three months ended March 31, 2022 compared to the same period in 2021, primarily driven by increased sales in our Biossance consumer product line to Sephora and initial sales of our new product lines that began in the third quarter of 2021.

Licenses and royalties revenue decreased by $134.5 million for the three months ended March 31, 2022 compared to the same period in 2021, due to the March 2021 sale of an intellectual property license to DSM, a related party.






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Costs and Operating Expenses

Costs and operating expenses were as follows:
Three Months Ended March 31,
(In thousands)20222021
Cost of products sold$48,995 $22,659 
Research and development26,358 23,332 
Sales, general and administrative106,916 37,922 
Total cost and operating expenses$182,269 $83,913 

Included in costs and operating expenses were the following amounts of non-cash stock-based compensation expense:
Three Months Ended March 31,
(In thousands)20222021
Cost of products sold$78 $63 
Research and development1,617 1,062 
Sales, general and administrative9,893 3,156 
Total stock-based compensation expense$11,588 $4,281 

Cost of Products Sold

Cost of products sold represents the direct cost to produce our products and includes the costs of raw materials and related transportation costs, labor and overhead, amounts paid to contract manufacturers, inventory write-downs resulting from applying lower of cost or net realizable value inventory adjustments, and costs related to production scale-up. Due to our product mix of higher-margin, higher-volume consumer products and lower-margin, large-batch fermentation ingredients products, our cost of products sold may not change proportionately with changes in renewable product revenue in any given period.

Cost of products sold increased by 116% to $49.0 million for the three months ended March 31, 2022 compared to the same period in 2021, primarily driven by a significant increase in sales volume of our consumer products. Our cost of products sold was also directly impacted by a significant increase in transportation costs and other supply chain logistics costs.

Research and Development Expenses

Research and development expenses increased by 13% to $26.4 million for the three months ended March 31, 2022 compared to the same period in 2021, primarily due to increased headcount and related employee compensation and benefit costs.

Sales, General and Administrative Expenses

Sales, general and administrative expenses increased by 182% to $106.9 million for the three months ended March 31, 2022 compared to the same period in 2021, primarily due to significant increases in sales and marketing spending, employee compensation costs due to a significant increase in headcount, and transaction costs related to our brand and business acquisitions. Increases in sales and marketing costs were the result of our steps to launch new consumer product lines and expand retail distribution and e-commerce sales.







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Other Income (Expense), Net
Three Months Ended March 31,
(In thousands)20222021
Interest expense$(5,263)$(5,813)
Gain (loss) from change in fair value of derivative instruments1,815 (22,745)
Gain (loss) from change in fair value of debt20,796 (326,785)
Loss upon extinguishment of debt— (27,313)
Other expense, net(3,052)(678)
Total other income (expense), net$14,296 $(383,334)

Three months ended March 31, 2022

Total other income, net was $14.3 million for the three months ended March 31, 2022, compared to total other expense of $383.3 million for the same period in 2021. The $397.6 million improvement was primarily comprised of a $347.6 million change from a loss to a gain in the change in fair value of debt, no loss upon extinguishment of debt in 2022 as compared to a $27.3 million loss in 2021, and a $24.6 million change from a loss to a gain in the change in fair value of derivative instruments. The fluctuations to changes in fair value of debt and derivatives were driven by a decrease in our stock price during the three months ended March 31, 2022, resulting in lower fair value of the underlying debt and equity instruments. See Note 3, "Fair Value Measurement" in Part I, Item 1 of this Quarterly Report on Form 10-Q for details regarding our outstanding derivative instruments.

Provision for Income Taxes

For the three months ended March 31, 2022, we recorded a tax benefit of $0.8 million related to a tax benefit in the United Kingdom. For the three months ended March 31, 2021, we recorded a tax provision of $0.1 million related to accrued interest on uncertain tax positions.

Liquidity and Capital Resources
(In thousands)March 31,
2022
December 31,
2021
Working capital$204,719 $369,407 
Cash and cash equivalents$287,886 $483,462 
Debt principal and lease obligations$786,345 $768,656 
Accumulated deficit$(2,458,973)$(2,357,661)
Three Months Ended March 31,
(In thousands)20222021
Net cash provided by (used in):
Operating activities$(152,442)$108,651 
Investing activities$(47,286)$(2,493)
Financing activities$3,958 $7,529 

Liquidity

We have incurred operating losses since our inception, and we expect to continue to incur losses and negative cash flows from operations through at least the next 12 months following the issuance of this Quarterly Report on Form 10-Q. As of March 31, 2022, we had working capital of $204.7 million, an accumulated deficit of $2.5 billion, and cash and cash equivalents of $287.9 million.

As of March 31, 2022, the principal amounts due under our debt instruments (including related party debt) totaled $741.1 million, of which $51.1 million is classified as current. However, substantially all of the current principal due is related party debt that is convertible into shares of the Company’s common stock at $3.00 per share, which we anticipate will convert into common shares at maturity on July 1, 2022. This debt agreement contains various financial and non-financial covenants, including certain restrictions on our business — including restrictions on additional indebtedness, material adverse effect and






34



cross default provisions — that could cause us to be at risk of default. A failure to comply with the covenants and other provisions of this debt instrument, including any failure to make payments when required, would generally result in events of default under such instrument, which could result in the acceleration of a substantial portion of such indebtedness. Acceleration would generally also constitute an event of default under our other outstanding debt instruments, which could result in the acceleration of a substantial portion of our debt repayment obligations.

Based on our cash and cash equivalents of $287.9 million as of March 31, 2022, we believe that we have adequate resources to fund our operations during the next 12 months from the date of filing this Quarterly Report on Form 10-Q. However, our ability to execute our planned operations, including the completion of our new fermentation facility in Brazil, will depend in large part, on our ability to (i) minimize the anticipated negative cash flows from operations during the 12 months from the date of this filing and (ii) achieve certain milestones under the March 2021 DSM transaction and the June 2021 Ingredion transaction (see Note 10, “Revenue” and Note 5, "Mezzanine Equity”, respectively in Part II, Item 8 of our 2021 Form 10-K for additional information), all of which are uncertain and/or outside of our control.

Our operating plan for the remainder of 2022 contemplates a significant reduction in net operating cash outflows as compared to the year ended December 31, 2021, resulting from (i) revenue growth from sales of existing and new products with positive gross margins, (ii) reduced production costs as a result of technical developments and transitioning to the new manufacturing facility during the second half of 2022, and (iii) an increase in cash inflows from milestone royalties under the DSM and Ingredion license agreements. If we are unable to generate sufficient cash inflows from product sales, licenses and collaboration arrangements, we will need to obtain additional funding from new equity or debt financings, which may not occur timely or on reasonable terms, if at all, and agree to burdensome covenants, grant further security interests in our assets, enter into collaboration and licensing arrangements that require us to relinquish commercial rights, or grant licenses on terms that are not favorable.

For details of our debt and equity, see the following Notes in Part I, Item 1 of this Quarterly Report on Form 10-Q:
Note 4, "Debt"
Note 5, "Mezzanine Equity"
Note 6, "Stockholders' Deficit"

Cash Flows during the Three Months Ended March 31, 2022 and 2021

Cash Flows from Operating Activities

Our primary uses of cash from operating activities are costs related to the production and sale of our products and personnel-related expenditures, offset by cash received from renewable product sales, licenses and royalties, and collaborations.

For the three months ended March 31, 2022, net cash used in operating activities was $152.4 million, consisting primarily of a $110.2 million net loss, $3.7 million of unfavorable non-cash adjustments that were primarily comprised of a $20.8 million gain from change in fair value of debt, partially offset by $11.6 million of stock-based compensation expense. Additionally, there was a $38.5 million increase in working capital.

For the three months ended March 31, 2021, net cash provided by operating activities was $108.7 million, consisting primarily of a $290.1 million net loss, partially offset by $384.7 million of favorable non-cash adjustments that were primarily comprised of a $326.8 million loss from change in fair value of debt, a $27.3 million loss upon extinguishment of debt, and a $22.7 million loss from change in fair value of derivative instruments. Additionally, there was a $14.0 million decrease in working capital.

Cash Flows from Investing Activities

For the three months ended March 31, 2022, net cash used in investing activities was $47.3 million, comprised of $33.8 million of property, plant and equipment purchases and $13.5 million of cash paid in business combinations.

For the three months ended March 31, 2021, net cash used in investing activities was $2.5 million, comprised of property, plant and equipment purchases.







35



Cash Flows from Financing Activities

For the three months ended March 31, 2022, net cash provided by financing activities was $4.0 million, primarily comprised of $4.0 million of proceeds from the exercise of warrants.
    
For the three months ended March 31, 2021, net cash provided by financing activities was $7.5 million, primarily comprised of $32.2 million of proceeds from the exercise of warrants and $1.9 million of proceeds from stock option exercises, partly offset by $23.2 million of debt principal payments, $2.5 million of issuance costs in connection with a debt modification, and $0.9 million of principal payments on financing leases.

Contractual Obligations

The following is a summary of our contractual obligations as of March 31, 2022:

Payable by year ending December 31,
(In thousands)
Total20222023202420252026Thereafter
Principal payments on debt$741,096 $50,041 $1,055 $— $— $690,000 $— 
Interest payments on debt
61,466 20,037 10,350 10,350 10,350 10,379 — 
Construction costs in connection with new production facility38,316 38,316 — — — — — 
Contract termination fees2,554 2,554 — — — — — 
Financing leases96 16 22 21 21 16 — 
Operating leases99,959 10,038 11,638 9,145 8,964 8,953 51,221 
Total$943,487 $121,002 $23,065 $19,516 $19,335 $709,348 $51,221 







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ITEM 3. QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK

The market risk inherent in our market risk sensitive instruments and positions is the potential loss arising from adverse changes in the price of our common stock, foreign currency exchange rates, interest rates and commodity prices.

Amyris Common Stock Price Risk

We are exposed to potential losses related to the price of our common stock. At each balance sheet date, the fair value of our derivative liabilities and certain of our outstanding debt instruments for which we have elected fair value accounting, is remeasured using current fair value inputs, one of which is the price of our common stock.

During any particular period, if the price of our common stock increases, there will likely be increases in the fair value of our derivative liabilities and our debt instruments for which we have elected fair value accounting. Such increases in fair value will result in losses in our condensed consolidated statements of operations from change in fair value of derivative instruments and from change in fair value of debt. Conversely, a decrease in the price of our stock during any particular period will likely result in gains in relation to these derivative and debt instruments. Given the current and historical volatility of our common stock price, any changes period-over-period have and could in the future result in a significant change in the fair value of our derivative liabilities and convertible debt instruments and significantly impact our net income during the period of change.

Foreign Currency Exchange Risk

Most of our sales contracts are denominated in U.S. dollars, and therefore our revenues are not currently subject to significant foreign currency risk.
The functional currency of our consolidated Brazilian subsidiary is the local currency (Brazilian Real), in which recurring business transactions occur. We do not use currency exchange contracts as hedges against our investment in that subsidiary.
Our permanent investment in Brazil was $150.7 million as of March 31, 2022 and $133.9 million as of December 31, 2021, using the exchange rate at each date. A hypothetical 10% adverse change in Brazilian Real exchange rates would have had an adverse impact to Other Comprehensive Loss of $15.1 million as of March 31, 2022 and $13.4 million as of December 31, 2021.
We have also evaluated foreign currency exposure in relation to our other non-U.S. Dollar denominated assets and liabilities and determined that there would be an immaterial effect on our results of operations from 10% exchange rate fluctuations between those currencies and the U.S. Dollar.

Interest Rate Risk

Our exposure to market risk for changes in interest rates relates primarily to our outstanding debt obligations, including embedded derivatives therein. We generally invest our cash in investments with short maturities or with frequent interest reset terms. Accordingly, our interest income fluctuates with short-term market conditions. As of March 31, 2022, our investment portfolio consisted of money market funds and certificates of deposit, both of which are highly liquid. Due to the short-term nature of our investment portfolio, we do not believe that an immediate 10% increase in interest rates would have a material effect on the fair value of our portfolio. Since we believe we have the ability to liquidate our investment portfolio, we expect that our operating results or cash flows would not be materially affected by a sudden change in market interest rates on the portfolio.

In addition, while not likely in the current and significantly extended low interest rate environment, changes in interest rates could significantly change the fair value of our embedded derivative liabilities.
    
As of March 31, 2022, all of our outstanding debt was in fixed rate instruments. As a result, changes in interest rates would not affect interest expense and payments in relation to our debt.

Commodity Price Risk
Our primary exposure to market risk for changes in commodity prices relates to our procurement of products from contract manufacturers and other suppliers whose prices are affected by the price of sugar feedstocks. Our suppliers manage exposure to this risk primarily through the use of feedstock pricing agreements.







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ITEM 2. UNREGISTERED SALES OF EQUITY SECURITIES AND USE OF PROCEEDS

None.






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ITEM 4. CONTROLS AND PROCEDURES

Evaluation of Disclosure Controls and Procedures

Our management, with the participation of our chief executive officer (CEO) and chief financial officer (CFO), has evaluated the effectiveness of our disclosure controls and procedures (as defined in Rules 13a- 15(e) and 15d- 15(e) under the Securities Exchange Act of 1934, as amended (Exchange Act)), as of the end of the period covered by this Quarterly Report on Form 10-Q. Based on such evaluation, our CEO and CFO have concluded that as of March 31, 2022, our disclosure controls and procedures are designed at a reasonable assurance level and are effective to provide reasonable assurance that information we are required to disclose in reports that we file or submit under the Exchange Act is recorded, processed, summarized, and reported within the time periods specified in the rules and forms of the Securities and Exchange Commission (SEC), and that such information is accumulated and communicated to our management, including our CEO and CFO, as appropriate, to allow timely decisions regarding required disclosure.

Changes in Internal Control

There were no changes in our internal control over financial reporting identified in management's evaluation pursuant to Rules 13a-15(d) or 15d-15(d) of the Exchange Act during the period covered by this Quarterly Report on Form 10-Q that materially affected, or are reasonably likely to materially affect, our internal control over financial reporting.

Limitations on Effectiveness of Controls and Procedures

In designing and evaluating the disclosure controls and procedures and internal control over financial reporting, management recognizes that any controls and procedures, no matter how well designed and operated, can provide only reasonable assurance of achieving the desired control objectives. In addition, the design of disclosure controls and procedures and internal control over financial reporting must reflect the fact that there are resource constraints and that management is required to apply judgment in evaluating the benefits of possible controls and procedures relative to their costs.






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PART II
ITEM 1. LEGAL PROCEEDINGS

For a description of our significant pending legal proceedings, please see Note 9, "Commitments and Contingencies" in the Notes to Condensed Consolidated Financial Statements included in Part I, Item 1 of this Quarterly Report on Form 10-Q.








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ITEM 1A. RISK FACTORS

The risks described in Part I, Item 1A, "Risk Factors" in our 2021 Form 10-K could materially and adversely affect our business, financial condition and results of operations, and the trading price of our common stock could decline. These risk factors do not identify all risks that we face; our operations could also be affected by factors that are not presently known to us or that we currently consider to be immaterial to our operations. Due to risks and uncertainties, known and unknown, our past financial results may not be a reliable indicator of future performance, and historical trends should not be used to anticipate results or trends in future periods. The “Risk Factors” section of the 2021 Form 10-K remains current in all material respects.

ITEM 3. DEFAULTS UPON SENIOR SECURITIES

None.

ITEM 4. MINE SAFETY DISCLOSURES

Not applicable.

ITEM 5. OTHER INFORMATION

None.






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ITEM 6. EXHIBITS
Exhibit No.DescriptionIncorporation by Reference
FormFile No.ExhibitFiling DateFiled Herewith
31.01x
31.02x
32.01b
x
32.02b
x
101.INSXBRL Instance Document
101.SCHXBRL Taxonomy Extension Schema Document
101.CALXBRL Taxonomy Extension Calculation Linkbase Document
101.DEFXBRL Taxonomy Extension Definition Linkbase Document
101.LABXBRL Taxonomy Extension Label Linkbase Document
101.PREXBRL Taxonomy Extension Presentation Linkbase Document
104Cover Page Interactive Data File (embedded within the Inline XBRL document)
b
This certification shall not be deemed “filed” for purposes of Section 18 of the Exchange Act or otherwise subject to the liability of that section, nor shall it be deemed incorporated by reference into any filing under the Securities Act or the Exchange Act.







42



SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this Quarterly Report on Form 10-Q to be signed on its behalf by the undersigned, thereunto duly authorized.
AMYRIS, INC.
By:
/s/ John G. Melo
John G. Melo
President and Chief Executive Officer
(Principal Executive Officer)
May 10, 2022
By:
/s/ Han Kieftenbeld
Han Kieftenbeld
Chief Financial Officer
(Principal Financial Officer)
May 10, 2022







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