I am a firm holder of AZM but..
From a GP's point of view, Xenical is very successful because the side effects are brought on by the patient consuming fat and fatty products. Therefore it stops the patient eating these products and losing weight not just due to the drug but due to an improved diet.
With Cetillistat, the side effects are reduced allowing the patient to consume fatty products, and if the are chronically obese they are likely to carry on with this poor diet thinking that the drug will reduce their weight.
There are obviously two ways of thinking about the side effects but just thought people should know that they can be a good thing.