Three key characteristics will define science this year — integrative, fast and small. Scientists will need to move out of their comfort zones and explore unknown domains. As science becomes more and more complicated, they will need to search for solutions in fields other than theirs. The biggest discoveries will be made through collaborations at the interface of science and technology.
Though genomics caused the gold rush in the earlier half of this decade, it does not provide a complete picture. Scientists have come to recognise the fact that genetic information is not of much use unless one can understand the work-horses of the body — the proteins. Proteins are modified by sugars or glycome, which forms the microenvironment around a cell. To get to the root of a disease and to develop newer and safer approaches of treatment, it will be necessary to understand how the flow of information between the genome, proteome and glycome is altered in the disease state.