I am not sure whether people are reading too much into this. Surely its just some shareholdings being placed in a nominee account now that they are in the CREST system. Ormiston Gore is controlled by Barry and its holding of 2,300,000 shares is clearly shown in the AIM listing document and is unchanged here.
As for Beth Edwards holding it would come as no surprise that a number of Bioprogress people got involved in the initial Cyan placing at 10p a share 2 years ago. At that time Bio were flying high and most of the investors had links to Bio and Barry in one way or another as would be fairly obvious comparing many of the names on this thread with Bio 2 years ago.