I have volonteered for that program, QAZWSX123 - don't know whether I will have placebo or not. I had been 5 years in remission, prior to which I had a course of 6-mp medication.
Anyway, aside from my health, the thread is concerned with CEN - the only reason that this has become a little diverted is to relate a current user of morphine who is not suffering any of the more common side effects.
I think that if P3 for M6g is successful AND the question of patent protection is addressed, then there is a case to prescribe an alternative to a proven drug for those who do display unwanted or uncontrolled side effects such as nausea.