TIDMSUMM 
 
+------------------------------------------------------------------------------+ 
|TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARESi                               | 
+------------------------------------------------------------------------------+ 
 
+----------------------------------------------+-------------------------------+ 
|1. Identity of the issuer or the underlying   |                               | 
|issuer                                        |                    Summit plc | 
|of existing shares to which voting rights are |                               | 
|attached:  ii                                 |                               | 
+----------------------------------------------+-------------------------------+ 
|2 Reason for the notification (please tick the appropriate box or boxes):     | 
+---------------------------------------------------------------------+--------+ 
|An acquisition or disposal of voting rights                          |    X   | 
+---------------------------------------------------------------------+--------+ 
|An acquisition or disposal of qualifying financial instruments which |        | 
|may result in the acquisition of shares already issued to which      |        | 
|voting rights are attached                                           |        | 
+---------------------------------------------------------------------+--------+ 
|An acquisition or disposal of instruments with similar economic      |        | 
|effect to qualifying financial instruments                           |        | 
+---------------------------------------------------------------------+--------+ 
|An event changing the breakdown of voting rights                     |        | 
+---------------------------------------------------------------------+--------+ 
|Other (please specify):                                              |        | 
+--------------------------------------+------------------------------+--------+ 
|3. Full name of person(s) subject to  | Polar Capital Global Healthcare Growth| 
|the                                   |                  and Income Trust Plc | 
|notification obligation: iii          |                                       | 
+--------------------------------------+---------------------------------------+ 
|4. Full name of shareholder(s)        |                                       | 
|(if different from 3.):iv             |                                       | 
+--------------------------------------+---------------------------------------+ 
|5. Date of the transaction and date on|                                       | 
|which the threshold is crossed or     |                         25 April 2012 | 
|reached:v                             |                                       | 
+--------------------------------------+---------------------------------------+ 
|6. Date on which issuer notified:     |                         25 April 2012 | 
+--------------------------------------+---------------------------------------+ 
|7. Threshold(s) that is/are crossed or|                                    3% | 
|reached:vi, vii                       |                                       | 
+--------------------------------------+---------------------------------------+ 
 
+-------------------------------------------------------------------------------+ 
|8. Notified details:                                                           | 
+-------------------------------------------------------------------------------+ 
|A: Voting rights attached to shares viii, ix                                   | 
+-------------+---------------------+-------------------------------------------+ 
|Class/type of|Situation previous   |Resulting situation after the triggering   | 
|shares       |to the triggering    |transaction                                | 
|             |transaction          |                                           | 
|if possible  +---------+-----------+-----------+---------------+---------------+ 
|using        |Number   |Number     |Number     |Number of      |% of  voting   | 
|the ISIN CODE|of       |of         |of shares  |voting         |rights x       | 
|             |Shares   |Voting     |           |rights         |               | 
|             |         |Rights     +-----------+------+--------+------+--------+ 
|             |         |           |Direct     |Direct|Indirect|Direct|Indirect| 
|             |         |           |           |xi    |xii     |      |        | 
+-------------+---------+-----------+-----------+------+--------+------+--------+ 
|             |         |           |           |      |        |      |        | 
|             |0        |           | 10,833,334|      |        | 3.08%|        | 
| GB00B02T3K57|         |           |           |      |        |      |        | 
+-------------+---------+-----------+-----------+------+--------+------+--------+ 
 
+-------------------------------------------------------------------------------+ 
|B: Qualifying Financial Instruments                                            | 
+-------------------------------------------------------------------------------+ 
|Resulting situation after the triggering transaction                           | 
+---------------+----------+---------------------+----------------+-------------+ 
|Type of        |Expiration|Exercise/            |Number of voting|% of voting  | 
|financial      |date xiii |Conversion Period xiv|rights that may |rights       | 
|instrument     |          |                     |be              |             | 
|               |          |                     |acquired if the |             | 
|               |          |                     |instrument is   |             | 
|               |          |                     |exercised/      |             | 
|               |          |                     |converted.      |             | 
+---------------+----------+---------------------+----------------+-------------+ 
|               |          |                     |                |             | 
+---------------+----------+---------------------+----------------+-------------+ 
 
+-------------------------------------------------------------------------------+ 
|C: Financial Instruments with similar economic effect to Qualifying Financial  | 
|Instruments xv, xvi                                                            | 
+-------------------------------------------------------------------------------+ 
|Resulting situation after the triggering transaction                           | 
+--------------+--------+----------+------------+----------------+--------------+ 
|Type of       |Exercise|Expiration|Exercise/   |Number of voting|% of voting   | 
|financial     |price   |date xvii |Conversion  |rights          |rights xix, xx| 
|instrument    |        |          |period xviii|instrument      |              | 
|              |        |          |            |refers to       |              | 
|              |        |          |            |                |              | 
+--------------+--------+----------+------------+----------------+-------+------+ 
|              |        |          |            |                |Nominal|Delta | 
|              |        |          |            |                +-------+------+ 
|              |        |          |            |                |       |      | 
+--------------+--------+----------+------------+----------------+-------+------+ 
 
+-------------------------------------------------------------------------------+ 
|Total (A+B+C)                                                                  | 
+------------------------------------+------------------------------------------+ 
|Number of voting rights             |Percentage of voting rights               | 
+------------------------------------+------------------------------------------+ 
| 10,833,334                         | 3.08%                                    | 
+------------------------------------+------------------------------------------+ 
 
+--------------------------------------------------------------------------+ 
|9. Chain of controlled undertakings through which the voting rights and/or| 
|the                                                                       | 
|financial instruments are effectively held, if applicable: xxi            | 
+--------------------------------------------------------------------------+ 
|                                                                          | 
|                                                                          | 
+--------------------------------------------------------------------------+ 
 
+--------------------------------------------------------------------------+ 
|Proxy Voting:                                                             | 
+-------------------------------------------------+------------------------+ 
|10. Name of the proxy holder:                    |                        | 
+-------------------------------------------------+------------------------+ 
|11. Number of voting rights proxy holder will    |                        | 
|cease                                            |                        | 
|to hold:                                         |                        | 
+-------------------------------------------------+------------------------+ 
|12. Date on which proxy holder will cease to hold|                        | 
|voting rights:                                   |                        | 
+-------------------------------------------------+------------------------+ 
 
+------------------------------+-------------------------------------------+ 
|                              |                                           | 
|13. Additional information:   |                                           | 
+------------------------------+-------------------------------------------+ 
|14. Contact name:             | Polar Capital LLP - Operations Department | 
+------------------------------+-------------------------------------------+ 
|15. Contact telephone number: |                       +44 (0)207 227 2700 | 
+------------------------------+-------------------------------------------+ 
 
 
 
 
 
 
This announcement is distributed by Thomson Reuters on behalf of 
Thomson Reuters clients. The owner of this announcement warrants that: 
(i) the releases contained herein are protected by copyright and 
    other applicable laws; and 
(ii) they are solely responsible for the content, accuracy and 
     originality of the information contained therein. 
 
Source: Summit Corporation PLC via Thomson Reuters ONE 
[HUG#1606130] 
 

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