Among the companies with shares expected to actively trade in Monday's session are Supernus Pharmaceuticals Inc. (SUPN), Edwards Group Ltd. (EVAC) and GTx Inc. (GTXI).

Supernus Pharmaceuticals, a specialty pharmaceutical company, received final approval from the U.S. Food and Drug Administration for its epilepsy treatment, Trokendi XR. Shares jumped 33% to $8.85 premarket as the company said it expects to launch the product and for it to be available in pharmacies over the next few weeks.

Edwards Group has agreed to be acquired by Atlas Copco AB (ATCO-A.SK, ATLKY) for up to $1.2 billion in a deal that will boost the vacuum pump maker's prospects for growth. The deal is valued at up to about $1.6 billion, including the assumption of debt. Atlas Copco will pay up to $10.50 a share to buy Edwards, representing a 24% premium to the company's Friday's closing price. The price includes a fixed cash payment of $9.25 at closing and an additional payment of up to $1.25 a share post-closing, depending on Edwards achieving certain milestones. Edwards shares rose 23% to $10.40 premarket.

GTx said two late-stage clinical trials of its treatment for patients with non-small cell lung cancer receiving chemotherapy failed to meet their endpoints. Shares tumbled 70% to $1.24 premarket.

Cobalt International Energy Inc. (CIE) said Monday that it had confirmed oil in a West African well, while it had not found oil in a well in the Gulf of Mexico. Shares of the oil-and-gas exploration company fell 12% to $25.80 premarket.

RBC Capital Markets downgraded Trulia Inc. (TRLA) to sector perform from outperform while maintaining its $47 price target, saying in a note to clients that with shares trading near its price target, the risk-reward profile for the online real-estate-listing service's stock has become "less compelling." Shares fell 4.6% to $44.00 premarket.

Activist investor Carl Icahn increased his ownership stake in energy producer Chesapeake Energy Corp. (CHK) to 9.98%, according to a regulatory filing. Chesapeake shares rose 2.8% to $25.70 in premarket trading.

 
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ConocoPhillips (COP) has sold its midstream asset in Trinidad and Tobago for $600 million to the National Gas Company of Trinidad and Tobago Ltd., as the exploration-and-production company continues to divest noncore assets.

Pinnacle Entertainment Inc. (PNK) has agreed to sell its Lumiere Casino and Hotels in St. Louis to Tropicana Entertainment Inc. (TPA) for $260 million in cash.

Saks Inc.'s (SKS) fiscal second-quarter loss widened as the retailer's overhead costs increased and sales grew more slowly than expected. The high-end retailer, which agreed in July to be acquired by Canadian firm Hudson's Bay Co. (HBC.T) in a $2.4 billion deal, said its moderate sales growth was driven by categories such as women's designer apparel and accessories, children's apparel and men's accessories.

Moody's Investors Service upgraded Sprouts Farmers Market Inc. (SFM) a notch, noting that the grocery chain's recent public launch eased its debt burden.

After a string of heavy losses and share-price declines, U.S. Steel Corp. (X) said Chief Executive John Surma is stepping down and will be succeeded by Mario Longhi, effective Sept. 1.

Write to Anna Prior at anna.prior@wsj.com

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