By Robbie Whelan 

On a recent weekday afternoon in Brooklyn, N.Y., Abdul Azam, store manager at Greenfield Pharmacy, sold soft drinks to teenagers, rang up orders for elderly customers buying medicine and scanned bar codes for a pile of parcels being shipped by United Parcel Service Inc.

Mr. Azam's pharmacy is one of a growing number of UPS Access Point locations -- small businesses like drug stores, dry cleaners or cafés with a small storage area where UPS drivers can leave packages for customers to retrieve later.

The managers at Greenfield, which sits just a block from the neighborhood's main subway station, have set up a storage rack in a back room where a pharmacist offers health consultations to customers. Mr. Azam scans packages with a device provided to him by UPS, collects a small fee for each one, and holds them until their owners come, show photo ID, and take them away.

For Mr. Azam, the Access Point location is helpful because customers picking up a package might also buy a tube of toothpaste or a bottle of aspirin: "We have a lot of new faces coming in" because of the package pickup service, he said.

But for UPS, Access Point locations solve the more crucial problem of failed deliveries: When recipients aren't home to receive packages, drivers have to make costly second and even third return trips. UPS said last month that it will expand the number of Access Point locations from just a few thousand locations now to 20,000 in North America, including new ones in Boston and the San Francisco Bay and the Washington, D.C., areas, by year-end.

As online shopping grows in popularity, more parcel-delivery services and retailers, plagued by the failed-package-delivery problem, are experimenting with ways to eliminate the often inefficient, maddening "last mile" of the supply chain altogether.

E-commerce hasn't turned out to be as profitable as delivery companies had hoped. Dropping off items purchased online at homes scattered across a neighborhood adds time, miles and costs to each delivery, while Amazon.com Inc. and its peers are able negotiate low prices based on their huge volumes.

Dropping off packages in bulk and creating incentives for consumers to fetch their parcels at nearby retailers or locker banks dramatically improves the economics of delivery.

As a result, UPS, FedEx Corp. and Deutsche Post DHL Group's DHL unit are investing heavily in new systems geared towards getting e-commerce customers to collect their orders anywhere but their homes.

FedEx offers a 24-hour locker system called "Ship&Get" in 31 cities in Texas, as well as in Memphis, Tenn., situating most lockers outside FedEx stores or Walgreens pharmacies. In August of last year, the U.S. Postal Service installed 17 "Gopost" lockers in New York and Washington as part of a pilot program. DHL, whose "Packstation" lockers are ubiquitous in Germany, is testing lockers in Plantation, Fla., and plans to install more in Orlando, New York and Miami this summer.

In Chicago, UPS is testing out brown-and-yellow, ATM-like smart lockers adjacent to a Staples store and an Aldi supermarket; customers can enter a numeric code and retrieve their packages.

Self-service pickup stations and lockers have been popular for years in Europe, where home delivery can be difficult and more of the population lives in dense urban centers than in the U.S.

DHL started building self-service lockers in Germany in 2001. Since then, the company has installed 2,700 locker banks, mostly in train stations, and opened 12,000 staffed parcel pickup points, including newsstands and small shops. The company hopes to expand the locker program elsewhere in Europe and the U.S.

Andrej Busch, chief executive of DHL Parcel Europe, said the cost of maintaining locker banks is offset by savings the company generates by not having to deliver each package to an individual customer's address. Most business-to-consumer deliveries are paid for by the shipping fees on each package. By leaving as many as 100 packages at a time at bulk drop-off points, DHL can spread the cost of each delivery over many dozens of shipping fees.

"The more parcels you can deliver to a single location, the lower the cost," Mr. Busch said. In the U.S., however, the challenge is finding the right place for pickup stations. "It's very, very early to say if this is going to work" in the U.S., he said. Fewer Americans commute by train than Europeans do, he said, and more Americans visit shopping centers as part of their regular routines. DHL is exploring putting lockers at shopping centers to "better cater to the American lifestyle."

For brick-and-mortar retailers, adding lockers outside stores for after-hour pickups would help eliminate the need to pay to ship online orders often covered by free shipping offers.

Several manufacturers of lockers are actively pitching their products to U.S. retailers and parcel-carriers, hoping to replicate their success on the other side of the Atlantic. InPost, Ltd., a Polish company that designs lockers that can be opened with a code sent by text message to the customer, recently presented its lockers at a logistics industry conference in Atlanta. The company has installed lockers that, it says, can save online retailers 30% per package on shipping costs in Poland, the Czech Republic, Russia and Ukraine; most recently, it installed about 1,000 in the U.K.

"The e-commerce shipper has a huge incentive to decrease their logistics cost," said Rafal Brzoska, InPost's founder.

InPost and its competitors are hoping, ultimately, that big-name retailers will commit to the "click-and-collect" model using lockers and implement it en masse in the U.S. Although few retailers have actually adopted locker technology, some say they are considering it.

"The idea of a locker concept is very much on our minds," said Terry Lundgren, chief executive of Macy's Inc., in a recent interview with The Wall Street Journal, although the company has no immediate plans to start using pick-up lockers, a spokesman said.

Any parcel-carrier or retailer experimenting with lockers is to some extent following the lead of Amazon, which began putting Amazon Lockers in grocery and convenience stores and drugstore outlets in Seattle, New York State and near Washington in 2011.

But some logistics industry experts doubt the need for lockers and pickup points. Satish Jindel, a long-time industry consultant and president of data firm ShipMatrix, Inc., said that failed deliveries aren't a big enough problem to warrant the investment parcel companies are making. A ShipMatrix analysis of 300 million deliveries from shippers to consumers by the major carriers found that only 1.5% of all parcels require a second delivery attempt, and only 0.8% of all parcels require a third attempt.

Mr. Jindel called UPS's Access Point program "an operations-driven initiative, not a market-driven" one. "It's only for deliveries in a bad neighborhood," he said. "What works in Europe is not going to work here."

Write to Robbie Whelan at robbie.whelan@wsj.com

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