A wave of newly insured patients coupled with fewer uninsured patients and a higher rate of admissions drove Universal Health Services Inc.'s revenue and profit growth in the first quarter, the hospital operator said Monday.

Shares, up 45% over the past 12 months, rose 2% in recent late trading to $123, just shy of a 52-week-high set Friday during regular trading.

Like its industry peers, Universal Health--which operates medical, surgical and behavioral-health facilities--has benefited from an increase in insured patients under the Affordable Care Act. UHS officials, however, said in a call with analysts following fourth-quarter results that they expect a bump from higher federal reimbursements under expanded Medicaid state programs to level off in 2015 as no additional states are projected to sign on to the expanded coverage.

In the most recent period, the provision for doubtful accounts--money set aside to cover the cost of unpaid bills--rose 4% to $94.6 million.

For the most recent period, the company reported a profit of $174.3 million, or $1.73 a share, compared with $138.1 million, or $1.38 a share, a year earlier. Excluding costs associated with the offering of electronic health records at its acute-care hospitals and other items, profit rose to $1.78 a share from $1.36 a share a year earlier.

Net revenue rose nearly 15% to $2.23 billion.

Analysts had projected earnings of $1.56 a share on revenue of $2.13 billion.

On a same-facility basis, acute-care hospitals reported a 12.2% increase in revenue with adjusted admissions up 5.7% and adjusted patient days increasing 7.5%. Meanwhile, revenue from its behavioral health hospitals rose 6.3%, with adjusted admissions increasing 6% and adjusted patient days 2.6%.

Write to Maria Armental at maria.armental@wsj.com

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