FORM 3
        
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Shine Daniel P

2. Date of Event Requiring Statement (MM/DD/YYYY)
1/1/2016 

3. Issuer Name and Ticker or Trading Symbol

THERMO FISHER SCIENTIFIC INC. [TMO]

(Last)        (First)        (Middle)

81 WYMAN STREET

4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                            _____ 10% Owner
___ X ___ Officer (give title below)          _____ Other (specify below)
Senior Vice President /

(Street)

WALTHAM, MA 02451       

(City)              (State)              (Zip)
5. If Amendment, Date Original Filed (MM/DD/YYYY)

 

6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person


Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4) 		2. Amount of Securities Beneficially Owned
(Instr. 4) 		3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5) 		4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock   16944   D    

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 4) 		2. Date Exercisable and Expiration Date
(MM/DD/YYYY) 		3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4) 		4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5) 		6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (Right to Buy)     (1) 3/5/2017   Common Stock   6000   $49.49   D    
Stock Option (Right to Buy)     (2) 2/23/2018   Common Stock   16900   $54.97   D    
Stock Option (Right to Buy)     (3) 12/12/2019   Common Stock   9375   $65.15   D    
Stock Option (Right to Buy)     (4) 2/26/2020   Common Stock   15400   $73.24   D    
Stock Option (Right to Buy)     (5) 2/26/2021   Common Stock   14800   $124.28   D    
Stock Option (Right to Buy)     (6) 2/25/2022   Common Stock   12600   $131.07   D    

Explanation of Responses:
( 1)  The option became exercisable in four equal annual installments. The first installment became exercisable on March 5, 2011, and the next three installments became exercisable on March 5, 2012, 2013 and 2014.
( 2)  The option became exercisable in four equal annual installments. The first installment became exercisable on February 23, 2012, and the next three installments became exercisable on February 23, 2013, 2014 and 2015.
( 3)  The option is exercisable in four equal annual installments. The first, second and third installments became exercisable on December 12, 2013, 2014 and 2015, and the fourth installment will become exercisable on December 12, 2016.
( 4)  The option is exercisable in four equal annual installments. The first and second installments became exercisable on February 26, 2014 and 2015, and the third and fourth installments will become exercisable on February 26, 2016 and 2017.
( 5)  The option is exercisable in four equal annual installments. The first installment became exercisable on February 26, 2015, and the second, third and fourth installments will become exercisable on February 26, 2016, 2017 and 2018.
( 6)  The option is exercisable in four equal annual installments beginning on February 25, 2016.

Remarks:
Exhibit List Exhibit 24 - Confirming Statement

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
Shine Daniel P
81 WYMAN STREET
WALTHAM, MA 02451

Senior Vice President

Signatures
/s/ Barbara J. Lucas, Attorney-in-Fact for Daniel P. Shine 1/7/2016
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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