By Noémie Bisserbe 

PARIS--Sanofi SA Chief executive Christopher Viehbacher said Tuesday the French drug maker would continue to focus on targeted acquisitions despite the recent resurgence in megadeals in the pharmaceutical sector.

Its U.S. rival Pfizer Inc. said Monday it had approached U.K.-based AstraZeneca regarding a takeover valued at nearly $100 billion, just a week after Novartis AG and GlaxoSmithKline PLC announced a series of transactions worth more than $20 billion--the latest in a series of deals that are fundamentally reshaping the industry.

"We have always been clear. If we can continue to bolt on to our growth platforms we'll continue to do so," Mr. Viehbacher told reporters. "And because we believe that we have critical mass in these areas, we don't feel the need to pay any price to acquire further businesses," he added.

Like other global pharmaceutical companies, Sanofi has been struggling with patent expiries on some of its best selling drugs, and efforts by cash-strapped governments in Europe to reduce health care spending.

Since taking over as CEO in December 2008, Mr. Viehbacher has steered the company into new business areas such as biotech, animal health and emerging markets.

But these moves have been slow to pay off. Inventory glitches and a crackdown on sales practices in China hurt revenue, forcing the company to cut earnings forecasts twice last year.

The recent spate of deal-making in the pharmaceutical sector as drug makers seek to create businesses capable of competing as leaders in their fields, has led analysts to speculate that pressure may increase on cash-rich Sanofi to look at acquisitions to revive growth.

Sanofi on Tuesday reported a 9.6% rise in first-quarter net profit, helped by lower costs related to earlier acquisitions.

The Paris-based pharmaceutical giant said net profit increased to EUR1.08 billion ($1.50 billion) in the three months ended March 31 from EUR989 million a year ago.

However, business net income, the company's term for adjusted income excluding the impact of acquisitions and divestments, fell 3.2% to EUR1.55 billion, below analyst forecasts of EUR1.57 billion.

Revenue declined 2.6% to EUR7.84 billion, dented by foreign exchange losses and lower animal health and vaccine sales.

Vaccine sales dropped 9.9% to EUR628 million in the first quarter because of a delay in supply of its infant pediatric vaccine Pentaxim in Mexico and China, while animal health revenue declined by 6.7% to EUR517 million due to generic competition. Pharmaceutical sales were also down 1.6% to EUR6.70 billion.

Genzyme, the drug maker's biotech unit posted a 22% jump in revenue to EUR566 million, driven by stronger sales of Aubagio, a medicine used to treat multiple sclerosis.

The company confirmed its guidance for 2014 of a 4% to 7% increase in business earnings per share at constant exchange rates.

Write to Noémie Bisserbe at noémie.bisserbe@wsj.com

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