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LONDON MARKETS: Shire Leads FTSE 100 Lower; Banks, Miners Off

By Sara Sjolin, MarketWatch LONDON (MarketWatch) -- Shire PLC led U.K. shares lower on Monday after a rival was cleared to market a generic version of one of Shire's drugs, while banks and miners declined ahead of euro-zone events later in the week. The FTSE 100 index fell 0.6% to 5,481.55, after closing out last week with a 0.6% gain. Pharma firm Shire tumbled the most in the index, down more than 10%, after the U.S. Food and Drug Administration approved a rival's generic version of its hyperactivity drug Adderall XR. Analysts at Goldman Sachs said that the approval is a "negative relative to our expectations" and that they had not expected a generic approval before 2014. "We assume Shire loses 50% of its market share," they said. Among other stocks driving losses in the U.K., mining firms headed south while metals prices were mixed. Heavyweight Rio Tinto PLC (RIO) lost 1%, Evraz PLC shed 0.8% and Vedanta Resources PLC gave up 0.9%. Banks were lower as investors looked toward a much anticipated European Union summit at the end of the week for any announcements on closer fiscal integration in the region and the creation of a banking union. Standard Chartered PLC ticked 0.9% lower, Lloyds Banking Group PLC (LYG) shed 0.7% and Barclays PLC gave up 0.6%. Food retailer Wm Morrison Supermarkets PLC dropped 2.3% after announcing that group Finance Director Richard Pennycook plans to step down from the board and leave the firm at the end of June 2013.

Stock News for Companhia Vale (RIO)
DateTimeHeadline
02/08/201611:24:00Rio Tinto Full-year 2015 -- Forecast
02/05/201616:02:00Six Members Resign From London Metal Exchange--Update
02/05/201615:50:00Six Members Resign From London Metal Exchange
02/05/201615:37:00Six Members Resign From London Metal Exchange
01/26/201617:25:00Rio Tinto to Sell Mount Pleasant Coal Deposit for US$224 Million...
01/18/201617:18:00Rio Tinto Records 11% Jump in Annual Iron-Ore Shipments
01/14/201611:28:00Rio Tinto Freezes All Salaries Including CEO's for 2016
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01/07/201607:10:00Oil and Mining Stocks Drag FTSE 100 Lower
01/06/201605:30:00Global Stocks Pressured by North Korea, China
12/30/201501:06:00Australia Shares Climb to Two-Month High
12/23/201523:13:00Australian Shares End Week Higher, Lifted by Resources Stocks
12/23/201517:27:00ADRs End Higher; Oil Majors Rise
12/20/201521:10:00Japan Leads Asian Shares Lower
12/18/201508:20:00Moody's Review of BHP's Credit Rating Piles On Pressure
12/18/201505:10:00Global Stocks Slip as Commodity Price Worries Return
12/18/201502:07:00Australia Shares End Flat, but Market Gains for the Week
12/15/201511:34:00Copper Prices Fall on Supply Outlook, Fed Jitters
12/15/201503:00:00Rio Tinto Lines Up Billions to Expand Massive Mongolian Mine
12/15/201502:36:00Rio Tinto Lines Up More Than $4 Billion to Expand Mongolian Copper...

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