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LONDON MARKETS: Shire Leads FTSE 100 Lower; Banks, Miners Off

By Sara Sjolin, MarketWatch LONDON (MarketWatch) -- Shire PLC led U.K. shares lower on Monday after a rival was cleared to market a generic version of one of Shire's drugs, while banks and miners declined ahead of euro-zone events later in the week. The FTSE 100 index fell 0.6% to 5,481.55, after closing out last week with a 0.6% gain. Pharma firm Shire tumbled the most in the index, down more than 10%, after the U.S. Food and Drug Administration approved a rival's generic version of its hyperactivity drug Adderall XR. Analysts at Goldman Sachs said that the approval is a "negative relative to our expectations" and that they had not expected a generic approval before 2014. "We assume Shire loses 50% of its market share," they said. Among other stocks driving losses in the U.K., mining firms headed south while metals prices were mixed. Heavyweight Rio Tinto PLC (RIO) lost 1%, Evraz PLC shed 0.8% and Vedanta Resources PLC gave up 0.9%. Banks were lower as investors looked toward a much anticipated European Union summit at the end of the week for any announcements on closer fiscal integration in the region and the creation of a banking union. Standard Chartered PLC ticked 0.9% lower, Lloyds Banking Group PLC (LYG) shed 0.7% and Barclays PLC gave up 0.6%. Food retailer Wm Morrison Supermarkets PLC dropped 2.3% after announcing that group Finance Director Richard Pennycook plans to step down from the board and leave the firm at the end of June 2013.

Stock News for Companhia Vale (RIO)
DateTimeHeadline
04/27/201509:33:47Rio Tinto plc's "Buy" Rating Reiterated at Deutsche Bank (RIO)
04/27/201501:03:35Asian Shares Rise, Mining Stocks Lift Sydney-- Update
04/25/201511:00:0310 Most Profitable Companies in Commodities
04/24/201512:36:12LONDON MARKETS: FTSE 100 Advances As HSBC Shares Jump
04/24/201506:59:12LONDON MARKETS: FTSE 100 On Track For A Weekly Advance; HSBC...
04/24/201504:12:46LONDON MARKETS: FTSE 100 Rises, On Track For A Weekly Advance
04/23/201513:24:28LONDON MARKETS: FTSE 100 Turns Higher As Miners Climb
04/23/201513:18:57LONDON MARKETS: FTSE 100 Turns Higher As Miners Climb
04/22/201509:22:04Rio Tinto plc Receives Outperform Rating from BNP Paribas (RIO)
04/22/201500:39:18BHP Iron Ore Output Rises Despite Glut Fears
04/21/201512:22:18LONDON MARKETS: FTSE 100 Rises As Sky Shares Jump, But Rio Tinto...
04/21/201509:34:46Rio Tinto plc Stock Rating Reaffirmed by JPMorgan Chase & Co...
04/21/201509:25:24RBC Capital Reaffirms "Sector Performer" Rating for Rio Tinto...
04/21/201509:22:53LONDON MARKETS: FTSE 100 Rises As Sky Shares Jump, But Rio Tinto...
04/21/201504:17:08LONDON MARKETS: FTSE 100 Climbs As ARM, Sky Bounce Higher
04/21/201503:37:27Rio Tinto plc Lowered to Equal Weight at Barclays (RIO)
04/21/201500:00:19Rio Tinto Iron-Ore Shipments Set to Rise
04/20/201523:54:04Rio Tinto Iron-Ore Shipments Set to Rise After Weak Start to...
04/20/201522:50:55Rio Tinto Quarterly Iron-Ore Shipments Fall
04/20/201518:00:30EUROPE MARKETS: European Stocks Buoyed By China Stimulus Move;...

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