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LONDON MARKETS: Shire Leads FTSE 100 Lower; Banks, Miners Off

By Sara Sjolin, MarketWatch LONDON (MarketWatch) -- Shire PLC led U.K. shares lower on Monday after a rival was cleared to market a generic version of one of Shire's drugs, while banks and miners declined ahead of euro-zone events later in the week. The FTSE 100 index fell 0.6% to 5,481.55, after closing out last week with a 0.6% gain. Pharma firm Shire tumbled the most in the index, down more than 10%, after the U.S. Food and Drug Administration approved a rival's generic version of its hyperactivity drug Adderall XR. Analysts at Goldman Sachs said that the approval is a "negative relative to our expectations" and that they had not expected a generic approval before 2014. "We assume Shire loses 50% of its market share," they said. Among other stocks driving losses in the U.K., mining firms headed south while metals prices were mixed. Heavyweight Rio Tinto PLC (RIO) lost 1%, Evraz PLC shed 0.8% and Vedanta Resources PLC gave up 0.9%. Banks were lower as investors looked toward a much anticipated European Union summit at the end of the week for any announcements on closer fiscal integration in the region and the creation of a banking union. Standard Chartered PLC ticked 0.9% lower, Lloyds Banking Group PLC (LYG) shed 0.7% and Barclays PLC gave up 0.6%. Food retailer Wm Morrison Supermarkets PLC dropped 2.3% after announcing that group Finance Director Richard Pennycook plans to step down from the board and leave the firm at the end of June 2013.

Stock News for Companhia Vale (RIO)
DateTimeHeadline
05/24/201603:58:00Rio Tinto Appoints New Head of Technology and Innovation
05/24/201603:37:00Rio Tinto PLC Statement re senior management changes
05/17/201600:40:00High Oil Prices Help Sentiment in Asia-Pacific Markets
05/17/201600:03:00Asian Shares: High Oil Prices Help Sentiment in Asia-Pacific...
05/12/201600:30:00Asia Stocks Dented by Weaker U.S., Japan Earnings
05/11/201616:50:00Miner Faces Scrutiny for Payments in Africa
05/11/201611:36:00Global Mining, Metals M&A Activity Continues to Shrink
05/10/201618:00:00Rio Tinto et Indspire présentent leur programme de bourse de...
05/10/201618:00:00Rio Tinto and Indspire showcase $2 million award program for...
05/10/201600:40:00Asia Stocks Mixed on Weaker Commodities, Yen
05/09/201618:43:00ADRs End Lower; AngloGold Ashanti, ArcelorMittal Decline
05/06/201604:00:00Rio Tinto Announces Latest Stage in Oyu Tolgoi Project
05/06/201603:23:00Rio Tinto To Start Next Stage Of Development At Mongolia Mine
05/06/201603:03:00Rio Tinto Maps Growth in Gloom -- WSJ
05/05/201608:32:00Rio Tinto Cuts Debt by $1.5 Billion Through Debt Tender Offers
05/05/201604:38:00Rio Tinto's Incoming CEO Focused on Cash, Projects -- Update
05/04/201620:15:00Rio Tinto's Incoming CEO Focused on Cash, Projects
05/04/201600:30:00Most Asian Stock Markets Fall Amid Renewed Weakness in Oil
04/28/201609:00:00Anglo American to Sell Brazilian Businesses to China Molybdenum...
04/28/201608:37:00Rio Tinto to Buy Back $1.359 Billion Debt

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