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LONDON MARKETS: Shire Leads FTSE 100 Lower; Banks, Miners Off

By Sara Sjolin, MarketWatch LONDON (MarketWatch) -- Shire PLC led U.K. shares lower on Monday after a rival was cleared to market a generic version of one of Shire's drugs, while banks and miners declined ahead of euro-zone events later in the week. The FTSE 100 index fell 0.6% to 5,481.55, after closing out last week with a 0.6% gain. Pharma firm Shire tumbled the most in the index, down more than 10%, after the U.S. Food and Drug Administration approved a rival's generic version of its hyperactivity drug Adderall XR. Analysts at Goldman Sachs said that the approval is a "negative relative to our expectations" and that they had not expected a generic approval before 2014. "We assume Shire loses 50% of its market share," they said. Among other stocks driving losses in the U.K., mining firms headed south while metals prices were mixed. Heavyweight Rio Tinto PLC (RIO) lost 1%, Evraz PLC shed 0.8% and Vedanta Resources PLC gave up 0.9%. Banks were lower as investors looked toward a much anticipated European Union summit at the end of the week for any announcements on closer fiscal integration in the region and the creation of a banking union. Standard Chartered PLC ticked 0.9% lower, Lloyds Banking Group PLC (LYG) shed 0.7% and Barclays PLC gave up 0.6%. Food retailer Wm Morrison Supermarkets PLC dropped 2.3% after announcing that group Finance Director Richard Pennycook plans to step down from the board and leave the firm at the end of June 2013.

Stock News for Companhia Vale (RIO)
DateTimeHeadline
05/04/201620:15:00Rio Tinto's Incoming CEO Focused on Cash, Projects
05/04/201600:30:00Most Asian Stock Markets Fall Amid Renewed Weakness in Oil
04/28/201609:00:00Anglo American to Sell Brazilian Businesses to China Molybdenum...
04/28/201608:37:00Rio Tinto to Buy Back $1.359 Billion Debt
04/27/201619:12:00Rio Tinto Prices Offers for US$1.5 Billion Debt Repurchase
04/21/201613:15:00Rio Tinto Plans to Buy Back $1.5 Billion in Debt -Update
04/21/201609:34:00Rio Tinto Plans to Buy Back $1.5 Billion in Debt due in 2017...
04/19/201618:12:00ADRs End Higher; Mining Firms Rise
04/19/201613:43:00Correction to Rio Tinto Trims Iron-Ore Production Update
04/18/201621:00:00Rio Tinto's Iron-Ore Shipments Fall Sharply
04/18/201619:27:00Rio Tinto's Iron-Ore Shipments ​Fall Sharply
04/18/201604:10:00Oil Prices Fall 5% in Late Asia Trading
04/18/201604:02:00Australia Stocks Pulled Lower by Energy Firms
04/18/201604:01:00Oil Prices Fall 5% in Late Asia Trading -- 3rd Update
04/17/201622:10:00Stocks Fall Sharply in Asia
04/14/201619:21:00Rio Tinto, Sinosteel Sign Iron-Ore Supply Deals
04/14/201603:37:00Rio Tinto Abandons Plan to Revise Supplier Payment Terms
04/13/201618:26:00ADRs End Higher; Steelmakers, Mining Companies Rise
04/09/201605:48:00Rio Tinto Doubles Payment Term to Help Free Up Cash
04/08/201611:00:00Rep. McCarthy Visits Rio Tinto Minerals’ Boron Mine

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