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LONDON MARKETS: Shire Leads FTSE 100 Lower; Banks, Miners Off

By Sara Sjolin, MarketWatch LONDON (MarketWatch) -- Shire PLC led U.K. shares lower on Monday after a rival was cleared to market a generic version of one of Shire's drugs, while banks and miners declined ahead of euro-zone events later in the week. The FTSE 100 index fell 0.6% to 5,481.55, after closing out last week with a 0.6% gain. Pharma firm Shire tumbled the most in the index, down more than 10%, after the U.S. Food and Drug Administration approved a rival's generic version of its hyperactivity drug Adderall XR. Analysts at Goldman Sachs said that the approval is a "negative relative to our expectations" and that they had not expected a generic approval before 2014. "We assume Shire loses 50% of its market share," they said. Among other stocks driving losses in the U.K., mining firms headed south while metals prices were mixed. Heavyweight Rio Tinto PLC (RIO) lost 1%, Evraz PLC shed 0.8% and Vedanta Resources PLC gave up 0.9%. Banks were lower as investors looked toward a much anticipated European Union summit at the end of the week for any announcements on closer fiscal integration in the region and the creation of a banking union. Standard Chartered PLC ticked 0.9% lower, Lloyds Banking Group PLC (LYG) shed 0.7% and Barclays PLC gave up 0.6%. Food retailer Wm Morrison Supermarkets PLC dropped 2.3% after announcing that group Finance Director Richard Pennycook plans to step down from the board and leave the firm at the end of June 2013.

Stock News for Companhia Vale (RIO)
DateTimeHeadline
03/27/201705:20:00Savannah Reports Maiden Resource Estimate for Ravene Deposit
03/10/201705:00:00Indonesian Ministry of Energy and Mineral Resources strongly...
03/09/201703:57:00Rio Tinto Chairman Jan du Plessis to Step Down -- Update
03/09/201703:07:00Rio Tinto Chairman Jan du Plessis to Step Down
03/09/201703:00:00BT Appoints Rio Tinto's Jan du Plessis as Its Next Chairman
03/08/201719:26:00Rio Tinto Chairman to Stand Down - Report
02/24/201702:04:00Australia Stocks Led Lower by Miners
02/22/201703:02:00Commodities Report: Mining Back to Unearthing Profit -- WSJ
02/21/201716:26:00Mining Companies Soar Back to Profit--3rd Update
02/21/201712:29:00Mining Companies Soar Back to Profit--2nd Update
02/21/201703:02:00Copper's Shine Returns Mining Firms Ride Copper Copper Pays Off...
02/19/201709:43:00Mining Giants Ride Copper's Wave
02/09/201717:28:00Shell CFO Among 3 Directors Named to Rio Tinto Board
02/09/201710:52:00Workers at BHP Billiton Copper Mine In Chile Go On Strike...
02/08/201705:16:00Rio Tinto Rewards Investors After Return to Profit
02/08/201701:42:00Rio Tinto Returns to Profit, Plans Share Buyback
02/07/201720:28:00Workers at World's Biggest Copper Mine Prepare for Strike
02/07/201700:34:00Rio Tinto Gifts Bunder Diamond Project to Government of Madhya...
02/04/201718:15:00Rio Tinto, Other Miners Get Pickup From Prices
02/04/201707:29:00Rio Tinto, Other Miners Get Pickup From Prices

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