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LONDON MARKETS: Shire Leads FTSE 100 Lower; Banks, Miners Off

By Sara Sjolin, MarketWatch LONDON (MarketWatch) -- Shire PLC led U.K. shares lower on Monday after a rival was cleared to market a generic version of one of Shire's drugs, while banks and miners declined ahead of euro-zone events later in the week. The FTSE 100 index fell 0.6% to 5,481.55, after closing out last week with a 0.6% gain. Pharma firm Shire tumbled the most in the index, down more than 10%, after the U.S. Food and Drug Administration approved a rival's generic version of its hyperactivity drug Adderall XR. Analysts at Goldman Sachs said that the approval is a "negative relative to our expectations" and that they had not expected a generic approval before 2014. "We assume Shire loses 50% of its market share," they said. Among other stocks driving losses in the U.K., mining firms headed south while metals prices were mixed. Heavyweight Rio Tinto PLC (RIO) lost 1%, Evraz PLC shed 0.8% and Vedanta Resources PLC gave up 0.9%. Banks were lower as investors looked toward a much anticipated European Union summit at the end of the week for any announcements on closer fiscal integration in the region and the creation of a banking union. Standard Chartered PLC ticked 0.9% lower, Lloyds Banking Group PLC (LYG) shed 0.7% and Barclays PLC gave up 0.6%. Food retailer Wm Morrison Supermarkets PLC dropped 2.3% after announcing that group Finance Director Richard Pennycook plans to step down from the board and leave the firm at the end of June 2013.

Stock News for Companhia Vale (RIO)
DateTimeHeadline
12/18/201412:00:14Norway Central Bank to Decide Oil Fund Exclusions
12/17/201419:10:10U.S. Court Rejects Vale Bid to Dismiss Rio Tinto Lawsuit
12/16/201415:52:20Joy Global's Joyless Year -- Ahead of the Tape
12/15/201417:10:18Tax Disputes Flair as Africa Fights 'Secret' Oil Deals
12/15/201413:23:59LONDON MARKETS: FTSE 100 Sheds Gains As Oil, Mining Stocks Drop
12/15/201413:23:54LONDON MARKETS: FTSE 100's Sheds Gains As Oil, Mining Stocks...
12/15/201413:01:34LONDON MARKETS: FTSE 100 Gains On Respite For Oil Shares
12/12/201418:27:28BSG Resources Seeks Judicial Review of UK's Role in Guinea Mine...
12/09/201416:03:38LONDON MARKETS: Tesco Hits 14-year Low In London After Warning
12/09/201411:54:10LONDON MARKETS: Tesco Tumbles In London To 14-year Low After...
12/09/201404:46:10LONDON MARKETS: FTSE 100 Down As Tesco Sinks, Chinese Worries...
12/09/201404:32:56LONDON MARKETS: FTSE 100 Down As Tesco Sinks, Chinese Data Weigh
12/09/201404:26:38LONDON MARKETS: FTSE 100 Down As Tesco Sinks, Chinese Data Weighs
12/08/201418:56:14EUROPE MARKETS: European Stocks Retreat From Seven-year High...
12/08/201405:33:29EUROPE MARKETS: European Stocks Drop From Seven-year High On...
12/08/201404:33:48LONDON MARKETS: FTSE 100 Under Pressure As Global-slowing Worries...
12/05/201416:47:41Vale May Consider Settling Suit Over Guinea Mining Rights
12/05/201408:26:04LONDON MARKETS: FTSE 100 Moves Toward Small Weekly Gain
12/04/201412:57:56LONDON MARKETS: U.K. Stocks Fall As ECB Puts Further Stimulus...
12/04/201408:41:14LONDON MARKETS: Resource-sector Shares Weigh On FTSE 100

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