U.S. stocks closed lower Monday, as the Dow Jones Industrial Average lost 130 points to 13880, the Standard & Poor's 500 Index fell 17 points to 1496, and the Nasdaq Composite slipped 1.5% to 3131. Among the companies with shares actively trading after hours are Idenix Pharmaceuticals Inc. (IDIX), Yum Brands Inc. (YUM) and Hologic Inc. (HOLX).

Idenix said it will discontinue its clinical development program for two of its investigational treatments for hepatitis C, after the U.S. Food and Drug Administration said the treatments would remain on clinical hold. Shares fell 3% to $4.59 after hours Monday.

Yum Brands' fourth-quarter earnings slipped 5.3% as the fast-food chain's same-store sales in China were hurt by negative publicity from a government review of poultry supplies there, though same-store sales in its U.S. business improved. Shares slipped 5.9% to $60.18 after hours as the company said it no longer expects earnings-per-share growth this year due to continued negative same-store sales and its expectation that it will take time to recover consumer confidence.

Hologic's fiscal first-quarter earnings plunged as the health-products company posted higher acquisition-related charges and other items that masked strong revenue growth. Shares were down 4.1% at $22.30 in recent after-hours trading as the company projected fiscal second-quarter earnings that missed expectations.

Rudolph Technologies Inc.'s (RTEC) fourth-quarter income surged on tax-related adjustments and higher revenue. But shares fell 6.4% to $12.50 after hours as the results missed Street expectations.

Thor Industries Inc. (THO) expects fiscal second-quarter sales that handily topped top expectations, amid strong growth in sales of its recreational vehicles. Shares were up 4.3% at $41.50 in recent after-hours trading.

 
   Regular Session Gainers: 

Oracle Corp. (ORCL) agreed to buy Acme Packet Inc. (APKT) for roughly $1.98 billion in cash, a deal the technology heavyweight said will accelerate the deployment of all-IP networks. Oracle will pay Acme's shareholders a per-share cash price of $29.25, a premium of 22% over Friday's close. Word of the deal lit a fire under networking names, namely fellow-broadband equipment maker Sonus Networks Inc. (SONS), BroadSoft Inc. (BSFT) and Procera Networks Inc. (PKT). Acme shares jumped 24%, while Oracle was off 3%.

Brown & Brown Inc.'s (BRO) fourth-quarter earnings rose 17% as the insurance agency and brokerage firm continued to report top-line growth from commissions and fees. Results beat Wall Street expectations.

Medical-device maker Cyberonics Inc. (CYBX) said a former employee voluntarily dismissed without prejudice a lawsuit he filed against the medical-device maker in a Massachusetts federal court. The lawsuit had raised "the potential for this case broadening to something larger" like a qui tam, or "whistleblower" suit, Jefferies analyst Raj Denhoy said in a note to clients.

Humana Inc. (HUM) kept an upbeat outlook for 2014 at its investor day Monday, as 2014 will be an important year for health insurers as major changes under the health-care law click into place.

MWI Veterinary Supply Inc.'s (MWIV) sizeable fiscal first-quarter beat-and-raise, coupled with cash flow more than doubling, shows why the company's stock has been an investor favorite, surging nearly six-fold the past four years. A strong IPO Friday for Pfizer Inc.'s (PFE) animal-health business Zoetis Inc. (ZTS) further highlights the big money and investor optimism for the space.

 
   Regular Session Decliners: 

Cabela's Inc. (CAB) shares fell after being downgraded to hold from buy by Feltl & Co. primarily on valuation. The firm is also concerned about credit-card-interchange income that last week came in significantly lower than expectations, a shortcoming noted by other investment firms. Interchange fees are paid by merchants to card issuers when a consumer swipes a card. Feltl feels the credit card-business is healthy with low charge-offs and delinquencies and rising receivables, but lower-than-expected interchange income "leads us to be more hesitant in our rating until we have more visibility into future trends."

Comfort Systems USA Inc.'s (FIX) 20% run over the last three months led BB&T to cut its rating to hold from buy, noting the valuation feels "full" and its sees tough times in the near future for the HVAC installation and maintenance provider. "While we continue to believe that nonresidential construction spending could recover more fully late this year or early next, we doubt that Comfort's [first half] outlook has improved since November," the firm said.

Gannett (GCI) shares started 2013 with a 10% jump after a second-half surge, so perhaps it should be no surprise that there's some sell-on-the-news activity after the media company's modest 4Q beat. "Results were slightly better [than expected], but no blowout," Evercore's Doug Arthur told Dow Jones. Meanwhile, print-ad demand remains in the doldrums, with that revenue down 6.5% once an extra week of activity is stripped out. Still, that decline was GCI's least of 2012, showing how the company has yet to see the bottom on that front after not seeing any print-ad growth since 2006.

Harris Teeter Supermarkets Inc.'s (HTSI) shares continued to slide after the supermarket chain reported fiscal first-quarter earnings below analysts' estimates as the supermarket chain responded to "aggressive pricing by competitors as well as low inflation and sluggish holiday sales (particularly Thanksgiving)," said BB&T in a Friday note to clients, as it cut its rating to hold.

Mercury General Corp. (MCY) swung to a surprise fourth-quarter loss as the insurance company recorded lower revenue driven by investment losses, while its catastrophe losses nearly tripled due to Hurricane Sandy. Results missed Wall Street estimates.

Royal Caribbean Cruises Ltd. (RCL) swung to a fourth-quarter loss as the cruise-ship company recorded a massive impairment charge, although net yields--a key industry metric measuring revenue per available cruise day--beat expectations. For the year ahead, the company projected earnings well below Wall Street forecasts.

After jumping more than 15% since late-December, Tiffany & Co. (TIF) retreated Monday after Monness Crespi Hardt cuts the jeweler to neutral, due to the rally and an "uncertain retail environment." The investment bank expects shares to be at current levels later this year.

Ultratech Inc. (UTEK) shares fell, following a Friday note by D.A. Davidson, downgrading the company to underperform. Davidson says "based on the revised 2013 outlook for 5%-10% EPS growth, combined with rising competition in the back end advanced packaging market, we believe UTEK no longer deserves a significant valuation premium over its peer group." The firm notes that it believes per-share earnings growth will be limited based on a combination of reduced advanced packaging sales--the company's highest margin produce line--and increased spending to try to seed the market with new products.

Yahoo Inc.'s (YHOO) biggest shareholder has sold 11 million shares, as it seeks to maintain a consistent percentage holding in the Internet firm amid Yahoo's aggressive stock buyback program.

-Write to Nathalie Tadena at nathalie.tadena@dowjones.com

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