By Brent Kendall 

WASHINGTON--Corporate deal making is at an eight-year high at the same time the Obama administration's antitrust enforcers are on their strongest footing ever, setting up a tug-of-war over industry consolidation.

The corporate executives and government officials now on opposite ends of the rope are in different places than when President Barack Obama took office in 2009, during the financial crisis. The president had pledged to reinvigorate antitrust enforcement, but his appointees at the Justice Department and Federal Trade Commission arrived at a time when the business community's appetite for significant mergers was limited.

Now, with the merger market emboldened by a favorable economic climate, antitrust enforcers, too, are gaining confidence, in part because of a favorable political climate. Members of both parties worry about companies growing in a way that could harm the economy.

"I think there's no question both agencies have taken a somewhat more aggressive approach to antitrust enforcement over the past several years, particularly in the second half of the Obama administration," said antitrust lawyer Barry Nigro of Fried, Frank, Harris, Shriver & Jacobson LLP.

"The more the government wins, the greater the level of confidence," Mr. Nigro added. And, "there are just a lot more deals than there were five or six years ago," he said.

Developments this week highlighted the breadth of the antitrust agencies' recent efforts. On Wednesday, the Justice Department filed suit to block General Electric Co.'s planned $3.3 billion sale of its appliance business to Electrolux AB. Like some others facing antitrust challenges, the companies vowed to vigorously defend the deal.

Hours before, the department confirmed it was investigating whether the nation's top airlines colluded on expansion plans.

On Tuesday, the department won a major appeals-court decision affirming an earlier court ruling against Apple Inc. that found the company liable for conspiring with publishers to raise the prices of e-books.

Department officials also are gearing up to scrutinize any mergers between top U.S. health insurers, which are courting one another for deals.

Two blocks down Pennsylvania Avenue, FTC officials were celebrating a win over would-be merger partners Sysco Corp. and US Foods Inc. The big food distributors abandoned their $3.5 billion deal Monday after a federal judge sided with the FTC.

Now, agency officials are getting ready for another court case, set to begin next month, in their l awsuit challenging a $1.9 billion combination of infection-prevention provider Steris Corp. and U.K. peer Synergy Health PLC.

Other pending deals are getting a close look from the agencies. The Justice Department is closely scrutinizing Expedia Inc.'s $1.3 billion takeover of rival Orbitz Worldwide Inc. and Halliburton Co.'s plan t o buy oil-field services rival Baker Hughes Inc.

The FTC, meanwhile, has been scrutinizing the proposed merger of office-supply retailers Staples Inc. and Office Depot Inc., a deal the agency derailed when the companies tried it nearly 20 years ago.

Corporate clients looking to do deals are aware of the agencies' enforcement activities and are moving antitrust risk assessments toward the top of their deal checklists, said Mr. Nigro, the antitrust attorney.

Despite the uptick in enforcement, many deals still are getting approved, even after detailed reviews by the government. The FTC recently cleared Reynolds American Inc.'s acquisition of rival cigarette maker Lorillard Inc. and on Thursday gave a green light to Dollar Tree Inc.'s deal to buy Family Dollar Stores Inc. after the discounters agreed to divest 330 stores.

"I don't think the level of activity is materially different from historical norms, recognizing that there is some streakiness to it," said William Blumenthal of Sidley Austin LLP, former general counsel at the FTC. As the pool of deals increases, the number that raise problems are likely to increase, too, he said. "That's just the numbers."

Some policy watchers, however, say government officials have shown a clear willingness to go to court, and that they are on a winning streak.

"The DOJ and FTC litigation success is influential," said George Washington University law professor William Kovacic, a former FTC chairman during George W. Bush's administration. "That's how you get the attention of companies and the bar."

What's tougher to gauge, he said, is whether the previous administration would have brought similar cases. He said that some of the deals being challenged appear to threaten the type of concentration that has traditionally concerned enforcers of both political parties.

The government's run of successes includes Comcast Corp.'s decision in April to abandon its planned acquisition of Time Warner Cable Inc., amid enforcers' concerns that a bigger Comcast could harm video programmers and the broadband market.

Days later, Justice Department objections helped sink a deal in the semiconductor industry, between Applied Materials Inc. and Tokyo Electron Ltd. In March, the department watched as two leading movie-theater advertising firms, National CineMedia Inc. and Screenvision LLC, folded tent on their planned tie-up, just ahead of a trial on the government's lawsuit to block the merger.

The Sysco matter was the commission's highest-profile merger case in eight years. The FTC's three Obama appointees had a lot riding on the outcome because the commission's two Republicans didn't support the lawsuit.

Last month, a federal judge in Washington ruled that combining the nation's top two food distributors was likely to suppress competition and hurt restaurants and other food-service businesses.

The Sysco ruling made investors in Staples and Office Depot jittery about whether it might embolden the FTC to take a harder line on the proposed tie-up of the two retailers. Shares in both companies dropped after the ruling.

The Justice Department's antitrust chief, Bill Baer, and other officials at an American Bar Association conference this spring suggested companies at times may be pushing the envelope in an exuberant climate for deals. "There are some ideas that should never get out of the boardroom," Mr. Baer said.

On Wednesday, antitrust lawyer Joe Sims, representing Electrolux in the GE deal, said the department's effort to block the transaction was inconsistent with the agency's 2006 decision under the Bush administration to approve Whirlpool Corp.'s acquisition of Maytag Corp. The biggest different between the two Justice Department outcomes, he said, "is we have a different set of decision-makers."

Antitrust lawyers say Mr. Baer at the Justice Department and Debbie Feinstein, the competition chief at the FTC, aren't shy about following their convictions in making decisions.

Both have served multiple stints at the antitrust agencies, and both have extensive private-practice experience--at the law firm Arnold & Porter--representing merging companies.

"Both of them take their government representation very seriously, just as they did when they were representing companies and individuals," said Fried Frank's Mr. Nigro.

Not everyone regards the agencies' latest antitrust moves as a sign of strength. Some critics cite the agencies' handling of airline-industry consolidation as an example.

Cleveland State University law professor Christopher Sagers, said the Justice Department allowed the airline industry to grow more concentrated when it settled a 2013 lawsuit and allowed American Airlines' AMR Corp. and US Airways Group Inc. to merge.

"DOJ missed its shot," Mr. Sagers said. "It was the antitrust mistake of the century."

Thomas Gryta and Drew Fitzgerald contributed to this article.

Write to Brent Kendall at brent.kendall@wsj.com

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