By Josie Cox 

The Russian ruble hit a fresh record low against the U.S. dollar Monday, burned by continuing fighting in Ukraine over the weekend and European Commission President José Manuel Barroso warning that the situation was approaching "a point of no return."

The dollar rose by 1.2% to 37.50 against the ruble in early trade, surpassing the previous record set on Friday. Moscow's Micex slipped into the red having clung to a slim gain earlier in the day, while the dollar-traded RTS index lost 1.5%. Since last Monday, the Micex is down just over 3.5%, while the RTS has declined by almost 7%.

On Sunday, Ukrainian government forces lost more ground to Russian-backed separatists in heavy fighting in the east of the country. While on Saturday, European leaders threatened to impose more sanctions on Moscow if it doesn't end its support for the rebels.

"While guns are firing there is no way one could expect the market situation to normalize. The peak isn't passed yet," said Igor Akinshin, a dealer at Alfa Bank in Moscow.

Egor Fedorov, an analyst at ING Bank in Moscow said that pressure was also being heaped on the currency by reports the U.K. has proposed banning Russian banks from the SWIFT network.

"That could result in short-term disruptions in interbank payments and security settlements," Mr. Fedorov said. Andrew MacFarlane, a strategist at Mitsubishi UFJ Securities International PLC said that for the time being, "obtaining full European Union agreement on that may prove difficult."

European stocks put in a lackluster performance Monday too, chiefly weighed by the geopolitical tensions but also by data showing that manufacturing activity in the euro zone slowed even more sharply than first estimated in August, due in part to a weaker performance than first estimated from Germany.

By midmorning the Stoxx Europe 600 was flat on the day, while the U.K's FTSE lost 0.1%, Germany's DAX 0.2% and France's CAC 0.3%. In the U.S., the S&P 500 was indicated falling 0.1%. Futures, however, don't necessarily reflect moves after the opening bell.

The euro continued its slow slide against the greenback, touching a near-year low of $1.3119 before rate announcements from both the European Central Bank and the Bank of England later in the week.

Several banks, including BNP Paribas, RBC and Nomura, expect the ECB to trim interest rates in a further bid to fuel the sluggish recovery.

Last month, ECB President Mario Draghi hinted that the central bank could be preparing further stimulus, even raising the prospect of quantitative easing. Some economists have said, however, that the central bank is likely to want to gauge the impact of its June measures and assess the take up of the targeted longer-term refinancing operation before taking further action.

Back in equity markets Swiss drug maker Novartis AG led the pan-European index, adding more than 3% after a positive testing of its LCZ696 heart drug. Fabian Wenner, an analyst at Kepler Cheuvreux, raised his target price to 87 Swiss francs from 81 francs.

France's Iliad SA, which is trying to buy U.S. operator T-Mobile, was one of the biggest losers on the index after the telecom operator reported a fall in first-half net profit on Friday.

In commodities markets Brent crude oil lost 0.15% to trade at $103.04 a barrel, while gold added 0.1% to $1,288.50.

-- Andrey Ostroukh in Moscow contributed to this article

Write to Josie Cox at josie.cox@wsj.com

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