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WSJ BLOG/Health: New Caution Urged Over Sole Oral MS Drug On the Market

(This story has been posted on The Wall Street Journal Online's Health Blog at http://blogs.wsj.com/health.) The FDA says the only oral multiple-sclerosis drug on the market -- Novartis's Gilenya -- shouldn't be used in patients with a recent history of stroke or some heart problems. As WSJ reports, a safety review of the treatment was prompted by a report in November of a 59-year-old patient dying in the U.S. less than a day after taking the first dose of the drug. Although the agency said an exact cause of the patient's death couldn't be identified, it continues to recommend that doctors closely monitor the hearts of patients after they have been given the first dose of the drug because the treatment can lower a person's heart rate temporarily. Patients who have had a stroke or heart trouble within the past six months shouldn't take the drug, the FDA says. It also shouldn't be used in patients taking some kinds of medicines to treat heart arrhythmias. The FDA warning comes after Europe's drug regulator last month requested stronger safety warnings. The U.S. agency is currently reviewing another oral MS drug from Biogen Idec designed to work through a different mechanism than Gilenya. -For continuously updated news from The Wall Street Journal, see WSJ.com at http://wsj.com.

Stock News for Novartis (NVS)
DateTimeHeadline
10/23/201407:33:40Novartis 3Q 2014 -- Forecast
10/10/201404:08:25Oxford Biomedica Inks New Collaboration Pact with Novartis
10/03/201411:32:27EU Approves Acquisition of Novartis Animal Health Division by...
09/22/201412:43:39Germany's Merck to Buy Sigma-Aldrich for $17 Billion--2nd Update
09/01/201412:45:13EUROPE MARKETS: Novartis Climbs, Iliad Drops: European Movers
09/01/201412:01:47EUROPE MARKETS: Novartis Up, Iliad Drops: European Movers
09/01/201408:27:44Ruble Hits New Record Low Against Dollar
08/29/201412:46:16Zurich Stocks Rise; Novartis Drug Test Results Eyed -- Market...
08/18/201412:40:12Zurich Stocks Mostly Higher; Swisscom Down -- Market Talk
08/01/201412:26:48LONDON MARKETS: FTSE 100 Slumps For Third Day As Miners, Banks...
07/28/201402:37:21Novartis Gets EU Approval For Glaucoma Drug
07/25/201407:44:11Drug Companies Oppose Moves to Reimburse Off-Label Medicine
07/17/201418:27:37ADR Shares End Lower; SAP Shares Trade Actively
07/16/201418:17:45Novartis 2Q Results -- Forecast
07/15/201417:53:10ADR Shares End Mixed; British American Tobacco Shares Trade Actively
07/15/201416:58:23Novartis, Google Team Up on Lenses -- Update
07/07/201415:20:45Novartis Wins 'Breakthrough' Status for Leukemia Treatment
07/02/201417:32:10ADR Shares End Mixed; Telefonica, Veolia Environnement Shares...
06/19/201409:25:15Actavis Generic Exelon Patch Found to Infringe on Patents
06/18/201417:07:21ADR Shares End Higher

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