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WSJ BLOG/Health: New Caution Urged Over Sole Oral MS Drug On the Market

(This story has been posted on The Wall Street Journal Online's Health Blog at http://blogs.wsj.com/health.) The FDA says the only oral multiple-sclerosis drug on the market -- Novartis's Gilenya -- shouldn't be used in patients with a recent history of stroke or some heart problems. As WSJ reports, a safety review of the treatment was prompted by a report in November of a 59-year-old patient dying in the U.S. less than a day after taking the first dose of the drug. Although the agency said an exact cause of the patient's death couldn't be identified, it continues to recommend that doctors closely monitor the hearts of patients after they have been given the first dose of the drug because the treatment can lower a person's heart rate temporarily. Patients who have had a stroke or heart trouble within the past six months shouldn't take the drug, the FDA says. It also shouldn't be used in patients taking some kinds of medicines to treat heart arrhythmias. The FDA warning comes after Europe's drug regulator last month requested stronger safety warnings. The U.S. agency is currently reviewing another oral MS drug from Biogen Idec designed to work through a different mechanism than Gilenya. -For continuously updated news from The Wall Street Journal, see WSJ.com at http://wsj.com.

Stock News for Novartis (NVS)
DateTimeHeadline
04/10/201412:25:40Zurich Stocks See Gains
04/09/201408:34:24Novartis Names New Alcon, Sandoz Division Heads -- Update
04/09/201402:50:35Novartis Names New Alcon, Sandoz Division Heads
04/03/201417:12:35ADR Shares End Lower; Vodafone Shares Active
04/02/201416:55:18ADR Shares End Higher; Noah Education Shares Active
03/31/201417:16:48ADR Shares End Higher; ING, Novartis Shares Active
03/31/201412:29:09EUROPE MARKETS: European Stocks End Mixed On Inflation Jitters
03/31/201411:07:25Supreme Court to Review Teva Appeal in Copaxone Patent Case
03/31/201410:29:55EUROPE MARKETS: European Stocks Push Higher After Weak Inflation
03/31/201406:22:12EUROPE MARKETS: European Stocks Pare Gains After Weak Inflation...
03/31/201404:55:55EUROPE MARKETS: European Stocks Firm Ahead Of Inflation Data
03/31/201403:25:12Novartis Heart Failure Pill Trial Ends Early on Positive Result
03/26/201413:54:19EUROPE MARKETS: Europe Stocks Higher As ECB Stokes Stimulus Hopes
03/22/201404:16:47Novartis Chairman Stresses Need for R&D Investment
03/21/201413:26:03Glaxo Wins Battle Over Asthma Drug
03/14/201417:12:21ADR Shares End Lower; GlaxoSmithKline Shares Active
03/14/201412:10:09HSBC Taps Symonds as Chairman of European Retail Unit
03/14/201411:55:38HSBC Appoints Former Novartis CFO as Chairman of European Retail...
03/07/201408:12:10EUROPE MARKETS: European Stocks Head For Weekly Loss Ahead Of...
02/26/201412:40:17Novartis to Shut U.K. Plant, Cut 361 Jobs

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