By Hester Plumridge 

Novo Nordisk A/S, the world's largest maker of insulin, cut its sales guidance for the full year because of challenges to its U.S. business, even as it reported a greater-than-expected rise in net profit.

The Danish drug maker cut its sales-growth guidance in local currencies for the full year to a range of 7% to 10%, from the 8%-to-11% range it gave in January, mainly because of a difficult rebate and contract environment in the U.S. and intensifying competition within the diabetes-treatment field.

The company maintained expectations of operating-profit growth of around 10% for the full year.

When asked about industry consolidation and Pfizer Inc.'s rebuffed takeover approach for AstraZeneca PLC, Novo's rival in diabetes treatment, Chief Financial Officer Jesper Brandgaard said Novo Nordisk was focused on organic growth rather than mergers and acquisitions.

"Novo Nordisk has no intentions of participating in the current consolidation in the industry," Mr. Brandgaard said on a conference call Thursday. "We believe that the focus that Novo Nordisk has is a key driver behind the success of the company."

Novo's sales in the first quarter grew 2% to 20.34 billion Danish kroner ($3.78 billion), from 19.98 billion kroner in the same quarter of the previous year. Analysts had been expecting sales of 20.91 billion kroner. Mr. Brandgaard said it had been a "challenging start to the year."

Sales were dented by the strength of the Danish krone, the impact of generic competition to Novo's diabetes drug Prandin in the U.S. and lower U.S. prescriptions of two of its diabetes treatments, Victoza and NovoLog, after the large pharmacy-benefit manager Express Scripts Holding Co. excluded them from coverage in January.

Express Scripts--which negotiates drug prices on behalf of employers and health insurers--took the treatments off its "preferred drug" list in January, meaning patients must pay full retail prices for them. It now recommends rival treatments, including Eli Lilly & Co.'s insulin Humalog and AstraZeneca's Byetta and Bydureon.

Sales growth was driven by Novo's portfolio of modern insulins, including 21% growth for insulin Levemir. Excluding the impact of currency effects, sales grew 7% in local currencies, Novo said.

First-quarter net profit rose 8% to 6.46 billion kroner, above the 6.29 billion kroner analysts were expecting, driven by increases of Novo's drug prices in the U.S., productivity gains, a shift toward sales of higher-margin products such as Victoza and lower spending on drug promotion.

Novo Nordisk said the launch of its new insulin Tresiba was going well, with sales growing to 80 million kroner from 9 million kroner in the first quarter. Recruitment in a clinical trial to look at cardiovascular outcomes of Tresiba is progressing ahead of plans, the company said.

Novo Nordisk shares were down by just over 3% in morning trading Thursday.

Write to Hester Plumridge at Hester.Plumridge@wsj.com

Subscribe to WSJ: http://online.wsj.com?mod=djnwires

Novo Nordisk (NYSE:NVO)
Historical Stock Chart
From Mar 2024 to Apr 2024 Click Here for more Novo Nordisk Charts.
Novo Nordisk (NYSE:NVO)
Historical Stock Chart
From Apr 2023 to Apr 2024 Click Here for more Novo Nordisk Charts.