By Jon Ostrower 

Boeing Co. reported a 19% jump in quarterly profit, beating expectations, and executives predicted that orders for its fuel-efficient jets will remain strong in 2015 despite concerns that falling oil prices could hamper demand.

The aerospace giant on Wednesday said it expects to deliver between 750 and 755 commercial jetliners in 2015, another industry record that could put it on pace to beat rival Airbus Group NV for the fourth year. Boeing Chief Executive Jim McNerney said the company also expects its order book this year to grow faster than it can build jets, increasing a backlog of jetliner orders that already stands at $440 billion based on list prices.

Boeing also gave some disappointing news, saying that manufacturing costs for its advanced 787 Dreamliners continued to climb faster than forecast. It said it expects to post "core" earnings, excluding part of its pension expenses driven by market volatility, of $8.20 to $8.40 a share for 2015, compared with $8.60 reported for 2014.

But Boeing's revenue guidance of $94.5 billion to $96.5 billion for 2015 topped expectations for $93.25 billion, indicating expectations of strong growth from the $90.76 billion reported for 2014. And Boeing projected a healthy increase in cash flow, a measure of financial performance closely watched by analysts.

Investors cheered the results and outlook, sending Boeing shares up more than 6% in early afternoon trading to $140.77 each--one of the stock's biggest jumps in years. The shares closed up $5.4% at $139.64.

With oil prices at the lowest levels since 2009, analysts have cautioned that new jet orders may be delayed as older less-efficient airplanes are less expensive to operate and stay in service longer. Mr. McNerney said cheaper fuel is beneficial to airlines and Boeing's long-term growth prospects. He added airline fleet planning schedules have "not substantially changed" as a result of the oil prices.

Boeing's commercial business had a record 2014, delivering 726 commercial jetliners in 2014 and 195 in the fourth quarter, which helped it generate $90.8 billion in revenue last year and $24.5 billion in the quarter, up 3%.

The company announced in December it would lift its stock buyback by $2 billion to $12 billion and increase its dividend 25%.

For the fourth quarter, Boeing reported profit of $1.47 billion, or $2.02 a share, up 19% from $1.23 billion, or $1.61 a share, a year earlier. Core earnings, and a metric closely watched by analysts, rose to $2.31 from $1.88.

But revenue at the defense, space and security division fell 14% to $7.59 billion. Boeing is restructuring the defense unit to counter military budget pressures and compete for a number of coming Pentagon competitions, including a new bomber. Mr. McNerney suggested that its St. Louis jet fighter plant might be home to the new $80 billion U.S. Air Force bomber program. Boeing is bidding for the deal in partnership with Lockheed Martin Corp., and faces competition from Northrop Grumman Corp. A winner is expected to be announced this summer.

Boeing's Dreamliner has been a sales success, drawing more than 1,000 orders since its first orders in 2004. Mr. McNerney said he expects orders to increase late in 2015 as it gets closer to available delivery dates.

But the Dreamliner has proved stubbornly expensive to make--on top of years of delays--with each jet costing more to build than Boeing can sell it for. The program has accumulated $26.15 billion in such losses over 228 deliveries, the company said, increasing around $1 billion during the quarter and exceeding even the largest estimates of around $800 million. Boeing expected those losses, known as deferred production costs, to top out around $25 billion, and now is signaling they could rise to around $28 billion.

Chief Financial Officer Greg Smith attributed the higher-than-expected costs to delayed contract renegotiations with suppliers as they master production, as well as to increased labor costs to introduce the new, longer 787-9 Dreamliner model into its factories and to investments that will improve productivity over the long term.

Mr. Smith said those per-unit losses would continue through the next nine months and maintained that the program would break even on each delivery by the end of 2015. Those losses will begin to reverse in 2016 when the company boosts Dreamliner output to 12 jets each month.

Boeing's accounting system enables it to spread the high early costs of the program over its expected average costs and revenues across 1,300 deliveries. By its own measures, the flagship long-range jet program is profitable and contributing to its quarterly earnings.

Chelsey Dulaney and Doug Cameron contributed to this article

Write to Jon Ostrower at jon.ostrower@wsj.com

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