By Peter Loftus 

Merck & Co. said it plans to lay off research-and-development workers at three East Coast sites in a shake-up of its early-stage drug-hunting efforts that also includes a new focus on the health effects of micro-organisms that populate the human body.

A Merck spokeswoman said the job cuts, and some employee transfers, would affect less than 10% of "discovery, preclinical and early development" employees in Kenilworth, N.J., Rahway, N.J., and North Wales, Pa. The company's headquarters are in Kenilworth.

The move marks the latest round of layoffs and reorganization for Merck's research unit, which was once known for cutting-edge drug development but which hit a fallow period late last decade.

Other large drugmakers including Pfizer Inc. and GlaxoSmithKline PLC also have cut R&D spending or reorganized research units in recent years to become more productive relative to their spending.

The Merck spokeswoman said the company is making the changes to allow it to have "earlier access to emerging external science and technology to augment our leading discovery and development capabilities."

At the same time, Merck plans to start new laboratories in Cambridge, Mass., and the San Francisco Bay Area, part of a trend among large drug makers to try to tap into hot clusters of biotechnology start-up activity and academic research.

Write to Peter Loftus at peter.loftus@wsj.com

 

(END) Dow Jones Newswires

July 12, 2016 14:31 ET (18:31 GMT)

Copyright (c) 2016 Dow Jones & Company, Inc.
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