By Annie Gasparro And Chelsey Dulaney 

McDonald's Corp. warned that sales and profits will remain under pressure for the next several months as it reported a 21% drop in earnings for the latest quarter, rounding out a dismal year for the fast-food chain that prompted core changes to its business.

The world's largest restaurant chain by revenue has struggled with weak sales in all major markets, most notably the U.S., amid changing consumer tastes and other hurdles. In the fourth quarter, customer traffic fell in Asia, Europe and the U.S.

"2014 was a challenging year for McDonald's around the world," Chief Executive Don Thompson said in a news release. "As we begin 2015, we are taking decisive action to regain momentum in sales, guest counts and market share." But, he added, "our business continues to face meaningful headwinds."

The results also offered a smidgen of positive news, as McDonald's logged its first monthly increase in same-store sales in the U.S. in more than a year. A key metric for the industry, sales at McDonald's locations that have been open at least 13 months rose 0.4% in the U.S. in December.

McDonald's said it would spend less on expansion and other projects this year, with a budget of $2 billion marking its lowest capital-expenditure plan in more than five years.

"We're exercising further financial discipline," Chief Financial Officer Pete Bensen said, as McDonald's works to regain momentum and improve the sales and profitability of its 36,000 restaurants around the world.

Investors had a muted reaction, with McDonald's shares oscillating slightly up and down in recent trading.

"The very little stock movement shows just how low expectations are," said Bill Smead, chief executive of Smead Capital Management, which owns about 168,000 shares of McDonald's stock.

Mr. Smead's fund has decreased its stake in McDonald's since the chain's problems surfaced in 2012, but he said he was confident in the long-term potential. "They have the best brand awareness, the best restaurant locations," he said.

In recent months, McDonald's has posted its worst U.S. same-store sales in more than a decade. Its increasingly complicated menu has slowed service, and younger customers are trading Big Macs for what they view are healthier, fresher options at made-to-order fast-casual chains like Chipotle Mexican Grill Inc.

The company also has been losing customers to more upscale burger and sandwich rivals such as Five Guys Holdings LLC and Chick-fil-A Inc. that focus on just a few menu items.

Mr. Thompson has outlined plans to fix the problems over the past few months--such as paring down the menu, more customizable options and higher-quality ingredients. This month, McDonald's launched a new marketing campaign in the U.S. with commercials and new packaging for food that focus on sprucing up its longtime "I'm lovin' it" slogan, under Chief Marketing Officer Deborah Wahl who joined in March. Despite her moves and the appointment of a U.S. chief in October, McDonald's still expects this month's same-store sales to decline.

Janney Capital Markets analyst Mark Kalinowski said he was surprised by the negative outlook among McDonald's franchisees in the U.S.

"Recent changes by McDonald's--perhaps most notably to advertising--don't seem to be generating any meaningful near-term lift in sales trends," he said in a note to investors ahead of Friday's release.

Overall, for the fourth quarter, McDonald's reported a profit of $1.1 billion, or $1.13 a share, down from $1.4 billion, or $1.40 a share, a year earlier. Revenue fell 7.3% to $6.57 billion. Analysts polled by Thomson Reuters had expected earnings of $1.22 a share on revenue of $6.68 billion.

McDonald's said global same-store sales fell 0.9%, including a 1.7% slide in the U.S. despite the uptick in December.

In the company's Asia-Pacific, Middle East and Africa region, sales at existing locations fell 4.8% as it continues to take a hit from a scandal with one of its meat suppliers that was accused of intentionally selling expired meat to restaurants in July. McDonald's performance in the region has improved somewhat, and it expects it to continue recovering over the next few months.

In Europe, McDonald's sales fell 1.1% as consumer-confidence issues in Russia added to broader economic softness in France and Germany. Russian authorities last year began inspecting many McDonald's restaurants and shutting some, widely seen as retaliation for U.S. sanctions in response to Russia's military incursion in Ukraine. More recently, sharp falls in oil prices and the Russian currency have hit the country's economy.

Write to Annie Gasparro at annie.gasparro@wsj.com and Chelsey Dulaney at Chelsey.Dulaney@wsj.com

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