By Margot Patrick and Max Colchester 

LONDON-- Standard Chartered PLC said Thursday that Chief Executive Peter Sands will step down in June and be replaced by former J.P. Morgan Chase & Co. executive Bill Winters, under pressure from shareholders and some executives who had grown frustrated with the bank's leadership.

The shake-up was far-reaching: The London-based, Asia-focused lender also said Chairman John Peace will step down in 2016 and that three longtime board members were also resigning. They will be replaced by two new independent directors.

While pressure has been building for months on Messrs. Peace and Sands, the magnitude of the shake-up surprised analysts and some bank executives. Mr. Sands, who was entering his ninth year as CEO, is one of the longest-serving chiefs of a major Western bank. Investors greeted the move, sending Standard Chartered's shares up about 2%.

Mr. Sands, who for months said he wasn't leaving even as the bank's share price tumbled, said it was "the right moment" to hand over the reins to Mr. Winters. "I am delighted that a banker of Bill's caliber will be leading the group through the next phase of development," he said.

Mr. Winters, who set up London-based asset-management firm Renshaw Bay after leaving J.P. Morgan in 2009, called Standard Chartered "a special bank." The 53-year-old American was co-CEO of J.P. Morgan's investment bank during a 26-year career at the U.S. lender. He also served at the U.K. Independent Commission on Banking, which played a key role in reforming Britain's banking sector after the financial crisis. He will join Standard Chartered on May 1 and start the CEO job in June.

While Mr. Winters in recent years has been a CEO candidate at other U.K. banks, his appointment Thursday is a surprise. He has little direct experience in Standard Chartered's core emerging markets or in commercial or retail lending. Mr. Peace said Mr. Winters "brings substantial financial experience from leading a successful global business and has an exceptional understanding of the global regulatory and conduct environment."

Mr. Peace dismissed concerns about Mr. Winters's limited experience and stressed that shareholders are supportive of the appointment. Mr. Peace declined to comment on how long Mike Rees, Standard Chartered's deputy CEO, plans to work for the bank.

Standard Chartered for a decade rode a wave of growth in Asian lending markets. But a slowdown in some of its key markets and rising regulatory costs have weighed on its results and led some analysts to question its strategy and capital adequacy. Mr. Sands laid out plans in January to shed thousands of jobs in Standard Chartered's retail bank and shut its stock-trading business, but the plans were regarded by many as insufficient to address the bank's broader problems.

That put pressure on Mr. Sands and Mr. Peace to prove they could turn the bank around or make way for those who could. In recent weeks, Mr. Sands was privately pressed by some executives and shareholders to resign, according to people familiar with the matter. At the World Economic Forum in Davos, Switzerland, last month, some clients who met with Standard Chartered executives expressed concerns to them about whether bank management was getting distracted, The Wall Street Journal reported.

"I was never going to be here forever," Mr. Sands said Thursday.

Analysts at Citigroup said the market was looking for a fresh start. "We believe investors will welcome this material change in [Standard Chartered's] leadership," they said.

Mr. Winters was only approached for the job a few weeks ago, according to a person familiar with the CEO search. Mr. Winters was seen as a strong candidate for his network of contacts, the fact that he ran the European and Asian investment bank at J.P. Morgan and because he got on well with Mr. Peace, the person said.

There were a handful of other candidates, some based in Asia, but U.K. regulatory requirements and political scrutiny made it very hard to lure them to a London-based role, people familiar with the matter said.

Temasek Holdings Pte. Ltd., Standard Chartered's biggest shareholder with 18%, said Mr. Winters brings "considerable experience as well as an excellent reputation for building good teams." The Singapore state investment company has been pressing the bank for years to make changes to its governance and appoint more independent directors, a slow process that was accelerated with the naming Thursday of two new directors.

Gay Huey Evans, a former Barclays and Citigroup executive who has also worked for the U.K.'s financial regulator, and Jasmine Whitbread, the chief executive of nonprofit organization Save the Children International, will join the board in April.

Longtime directors Ruth Markland, Paul Skinner and Oliver Stocken will step down in the coming months.

Standard Chartered will release full-year results Tuesday that are expected to show a rise in bad loans from customers hit by the commodities selloff. Some analysts said they expect Mr. Winters to take steps to boost the bank's capital buffers by selling new shares, a move that Mr. Sands has long resisted.

Write to Margot Patrick at margot.patrick@wsj.com

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