International stocks trading in New York closed mostly higher on Wednesday.

The BNY Mellon index of American depositary receipts edged up 0.43% to 143.62. The European index increased 0.59% to 144.94, the Asian index improved 0.3% to 148.16, the Latin American index eased 0.57% to 188.54 and the emerging markets index rose 0.21% to 237.21. ING Groep NV (ING, INGA.AE) was among the companies with ADRs that traded actively.

ING Groep NV (ING, INGA.AE) reported a rise in second-quarter profit as it continues to reap the benefits from its repositioning toward consumer and business lending in Europe. However, ADRs of the Netherlands' largest bank fell 4% to $16.37 as analysts voiced disappointment over weaker profitability and rising costs.

Deutsche Bank AG (DB, DBK.XE) has fired two senior trading executives for alleged lax supervision of a pair of more junior employees whose communications with clients allegedly violated the lender's policies, The Wall Street Journal reported Wednesday. The employees, who worked in the bank's New York office, are the latest traders to draw scrutiny for what they told clients in negotiations over the price of complex debt securities. ADRs edged up four cents to $34.06.

Write to Tess Stynes at tess.stynes@wsj.com

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