By Carla Mozee, MarketWatch

LONDON (MarketWatch) -- U.K. stocks vacillated between small gains and losses Wednesday, with news of a probe by regulators putting GlaxoSmithKline PLC shares among the session's decliners.

The FTSE 100 was up 2 points at 6,846.40, with sector losses led by miners as prices for gold, platinum and other metals were under pressure. Anglo-American shares gave up 1.9%, Rio Tinto PLC lost 1.6% and BHP Billiton PLC (BHP) fell 1.4%.

Glaxo shares sat near the bottom of the benchmark, losing 1.4% as the drug maker said British regulators are looking into its commercial practices. No details of the action were included in a Tuesday statement, but Glaxo said it will fully cooperate with the U.K.'s Serious Fraud Office.

The probe comes as Glaxo tries to clear up allegations from Chinese officials that executives orchestrated the bribery of doctors and health-care groups in China to boost drug sales.

But Smith & Nephew PLC shares rose 3%, scaling to the top of the FTSE, but they came off a stronger spike after medical-device maker Stryker Corp. (SYK) said it hadn't made a bid for the London-based artificial joints maker.

London Stock Exchange Group also advanced, rising 2.4% as the exchange operator was added to Credit Suisse's Europe focus list. The LSE's rating remained at outperform.

The FTSE 100 on Tuesdaylogged a 0.4% advance that left the index with its highest close in more than a week.

Outside of daily market moves, Bank of England Gov. Mark Carney on Tuesday called on bankers to reform behavior that lead to misdeeds in the financial sector that risk undermining public support for free markets.

More news from MarketWatch:

France's consumer spending drops in April.

A 401 (k) on autopilot risks going off course

Subscribe to WSJ: http://online.wsj.com?mod=djnwires

GSK (NYSE:GSK)
Historical Stock Chart
From Mar 2024 to Apr 2024 Click Here for more GSK Charts.
GSK (NYSE:GSK)
Historical Stock Chart
From Apr 2023 to Apr 2024 Click Here for more GSK Charts.