By Hester Plumridge 

LONDON--Polish prosecutors have charged 13 people in connection with a bribery investigation into GlaxoSmithKline PLC, Poland's Anti-Corruption Bureau said Monday.

A statement from the Polish agency came after the British Broadcasting Corp. reported that Glaxo is facing a criminal investigation for allegedly bribing doctors in Poland to promote its best-selling asthma drug Advair--marketed in Europe as Seretide--between 2010 and 2012.

The agency said it had received information about "possible irregularities." It declined to comment further.

Glaxo said in a statement Monday that an internal investigation "found evidence of inappropriate communication in contravention of GSK policy by a single employee. The employee concerned was reprimanded and disciplined as a result." Glaxo said it was cooperating fully with Polish authorities.

The newly disclosed probe comes as the U.K. company faces separate allegations its employees bribed doctors in China and the Middle East.

Chinese authorities last summer accused Glaxo of bribing doctors and, since then, have been investigating the company. Glaxo has said it appears some of its senior staff in China broke the law and is cooperating with the investigation.

In Iraq, a person familiar with Glaxo's Mideast operations emailed the company late last year to report allegations of bribery, in emails seen this month by The Wall Street Journal.

Glaxo is now investigating its business units in nine countries in the Gulf and Middle East region, and said in a statement it takes the allegations seriously and has put a temporary stop to interactions between employees and government officials in the region "to ensure any activity is in compliance with our policies and procedures."

In 2012, Glaxo paid a $3 billion fine--the largest healthcare-fraud settlement in U.S. history--after pleading guilty to illegally marketing drugs and withholding safety data. Glaxo said in December it was stopping all payments to doctors globally to attend conferences or speak about its drugs, a policy it expects to be in place world-wide by 2016.

Write to Hester Plumridge at Hester.Plumridge@wsj.com

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