DETROIT—U.S. safety regulators are investigating complaints that the power brake assist can fail on some Ford F-150 pickup trucks.

The National Highway Traffic Safety Administration said the probe covers about 250,000 pickups from 2011 and 2012 with 3.5-liter six-cylinder engines.

The agency said it has 32 complaints alleging that electric vacuum assist pumps can fail, causing loss of power brakes and increased braking effort. Two crashes were reported, but no injuries.

In all the complaints, no warnings were issued. The agency says the complaints are increasing, with about 60% coming in the past nine months.

Investigators will look into the cause of the problem and how often it happens. The probe could lead to a recall.

Ford said it is cooperating. Customers with problems should contact their dealer.

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