By Anora Mahmudova, MarketWatch

NEW YORK (MarketWatch) -- U.S. stocks fell on Tuesday with the financials leading the losses on the S&P 500. Investors were cautious as the crisis in Ukraine continued to flare up.

Premarket optimism stemming from deal news in the pharmaceutical industry was short-lived.

The S&P 500 (SPX) was 6 points, or 0.3%, lower at 1,877.60. Financials and consumer discretionary sector stocks led the losses. The Dow Jones Industrial Average (DJI) fell 77 points, or 0.5%, to 16,452.91. The Nasdaq Composite (RIXF) dropped 17 points, or 0.3%, to 4,119.33.

Follow MarketWatch's live blog of today's stock-market action.

"Traders are being cautious, as they should be, because of the situation between Ukraine and Russia," says Kim Caughey Forrest, senior equity analyst at Fort Pitt Capital.

"Today's trading is very atypical, there is very little volume and deal news, which usually a positive for markets is being ignored," she added.

The sole economic report on Tuesday was data on the U.S. trade deficit, which narrowed in March, as the nation boosted exports of gas, oil and commercial aircraft, the Commerce Department said. The deficit fell 3.6% to $40.4 billion, slightly above the consensus of $40 billion.

Twitter tumbles, Office Depot surges on earnings

In deal news, Merck (MRK) agreed to sell its consumer-products business, including the allergy-treatment Claritin and nasal decongestant Afrin, to German drug maker Bayer AG (MRK) for $14.2 billion. Shares fell 1.9%.

Office Depot Inc. shares (ODP) surged 18% to $4.94, after the electronics retailer raised its outlook for 2014 operating profit and said it plans to close at least 400 U.S. stores by the end of 2016.

Shares of Athenahealth (ATHN) fell 12%, after David Einhorn of Greenlight Capital said at a conference Monday that the health-information technology firm is "overpriced" and "caught up in a bubble."

American International Group Inc. (AIG) shares were hit, falling 2.8% after reporting a substantial fall in first-quarter profits.

Discovery Communications, Inc. (DISCA) shares dropped 3% after disappointing first-quarter results. The owner of Discovery Channel and Animal Planet said profit edge down 0.4% as higher expenses cut into revenues.

Twitter Inc. (TWTR) shares tumbled 10% as hundreds of millions of shares held by insiders became available for sale in the open market. The stock took a hit even after Twitter management sought to reassure investors by announcing that major investors were not planning to unload huge chunks of their shares.

DirecTV (DTV) shares rose 1.5% even as the company said first-quarter earnings fell 19%. The company, however, continued to boost its subscriber numbers, surpassing 38 million customers.

Quarterly results from media and entertainment conglomerate Disney (DIS), upscale grocer Whole Foods (WFM) as well as e-commerce and daily-deals company Groupon Inc. (GRPN) are due after Wall Street's regular close.

Disney (DIS) is projected to report second-quarter earnings of 96 cents a share, according to a consensus survey by FactSet, while Whole Foods is projected to report earnings of 41 cents a share in the second quarter. Groupon Inc. is forecast to post a loss of 3 cents a share in the first quarter.

European stocks lower, Asian market closed

Ahead of Wall Street's open, European stocks reversed earlier gains and moved lower.

On Tuesday, the Organization for Economic Cooperation and Development said the European Central Bank should immediately cut its benchmark interest rate, to end a period of too-low inflation in the euro zone.

Asian stocks were slightly higher, with Australia up after the country's central bank held interest rates steady. Markets in Japan, South Korea and Hong Kong were closed.

In the commodities markets Tuesday, gold (GCM4) futures fell slightly. Crude for June delivery (CLM4) gained slightly but still remained below the $100 a barrel level. Meanwhile, the pound (GBPUSD) bought $1.6980 and traded at levels not seen since at least 2009 after strong U.K. services data.

More must-reads from MarketWatch:

Mickey Mouse decouples from the U.S. economy

5 utility companies that are now takeover targets

A $68 million welcome to Apple

Subscribe to WSJ: http://online.wsj.com?mod=djnwires

Walt Disney (NYSE:DIS)
Historical Stock Chart
From Mar 2024 to Apr 2024 Click Here for more Walt Disney Charts.
Walt Disney (NYSE:DIS)
Historical Stock Chart
From Apr 2023 to Apr 2024 Click Here for more Walt Disney Charts.