By David Benoit 

Nelson Peltz scored a key recommendation in his fight to join the board of DuPont Co., as an influential proxy adviser backed his campaign to shake up the chemical giant.

Institutional Shareholder Services Inc. said Monday that DuPont shareholders should elect Mr. Peltz and John Myers, two of the four nominees Mr. Peltz's Trian Fund Management LP had put forward.

"This is not a broken company--but there is compelling evidence that the dissidents are onto something in their critique," ISS wrote. "Operating efficiency is not what it should be, yet instead of addressing the core issues, the board and management, at least in their communications with shareholders, are more inclined to obfuscation than accountability."

DuPont said in a statement that ISS reached the "wrong conclusion" and that the opinion was "ignoring the success of our transformative strategy and the value-destructive nature of Trian's break up agenda."

The company defended its current board as having the "right mix of experience and skills" and reiterated its concern that what it called Trian's "shadow management team" could harm the company.

DuPont shares rose 4.6% in afternoon trading to $74.79.

DuPont and Trian have been engaged in what has become a bitter proxy fight over the future of the chemical maker.

While both sides had tried to make offers to settle the campaign, both have been steadfast on the one breaking point: Whether Mr. Peltz deserves a seat on the board.

ISS came down on the side of Mr. Peltz on that issue, rejecting DuPont's arguments that his ideas have been reviewed already and that he would set up a "shadow management" that would interfere with running the business.

"The testimonials from prior boards on which Peltz has served suggest this is ultimately not a 'shadow management team' so much as a commitment to ensuring informed and effective advocacy participation in the boardroom," ISS wrote, adding that Mr. Peltz's election "thus seems clearly in the best interest of all shareholders."

ISS declined to pick a side on whether to break up the company, something Trian pressed for, although it more recently has said it would be open to other ideas.

"Arguably the biggest question raised in this entire proxy contest--should DuPont be broken up--turns out, after analysis of the numerous other aspects of the dissident critique, to be the easiest to answer," ISS wrote. "We don't know, and neither does anyone else outside the DuPont boardroom."

Trian says DuPont has underperformed its peers and that its underlying businesses are weighed down by a large corporate structure. The activist Trian says the board and management's performance warrants new voices and shareholder oversight.

DuPont has maintained that its stock has outperformed, that it is already reshaping itself with the plan to spin off its performance chemicals business and cut costs. It argues its board and management have performed well and engaged with shareholders and that Trian's ideas about breaking up the company would destroy value.

Write to David Benoit at david.benoit@wsj.com

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