By Anora Mahmudova, MarketWatch

NEW YORK (MarketWatch) -- U.S. stocks moved lower in early trade Thursday, as investors weighed disappointing earnings from Google and IBM against estimate-beating results from Goldman Sachs and Morgan Stanley.

Ahead of the opening bell, better-than-expected weekly jobless claims figures briefly boosted markets. Investors await manufacturing data from the Philadelphia Federal Reserve due at 10 a.m. Eastern.

Investors will focus on earnings, as 25 companies on the S&P 500 are scheduled to report profits on Thursday, according to FactSet.

The S&P 500 (SPX) was 5 points, or 0.3%, lower at 1,857.57, after three days of gains sent it into positive territory for the year.

The Dow Jones Industrial Average (DJI) shed 51 points, or 0.1%, to 16,398.58.

The Nasdaq Composite (RIXF) fell 20 points, or 0.5%, to 4,066.30.

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The number of people who applied for unemployment-insurance benefits ticked up by 2,000 to 304,000 in the week that ended April 12, a slight increase from the lowest level since 2007, signaling that employers are maintaining a slow pace of layoffs, according to government data released Thursday.

At 10 a.m. Eastern Time, the Federal Reserve Bank of Philadelphia will publish its monthly reading on regional manufacturers, with the gauge expected to show a slight improvement to 10 in April, from 9 in March.

Thursday has one of the busiest earnings schedules in the results season, and there also were notable reports late Wednesday.

Shares of IBM Corp. (IBM) dropped 4% after the tech bellwether late Wednesday reported an eighth-straight quarter of revenue declines and missed analyst expectations.

Google Inc. (GOOG) (GOOGL) dropped 4% after a disappointing earnings report published late Wednesday.

American Express Co.(AXP) fell 2% after it reported quarterly revenue that missed expectations late Wednesday.

Banking giant Goldman Sachs Group Inc. (GS) gained 1.3% after it reported first-quarter earnings above expectations.

Peer firm Morgan Stanley (MS), rose 3.7% after its profit topped estimates.

General Electric Co. (GE) said it made an adjusted 33 cents a share in the first quarter, slightly beating FactSet estimates of 32 cents a share. Shares gained 1.9%.

UnitedHealth Group Inc.(UNH) slid 5.6% after its earnings beat expectations, but revenue missed.

In other earnings news on Thursday, DuPont Co. (DD) reported adjusted first-quarter earnings of $1.58 a share, up from $1.56 in the year-ago period. Shares slipped 1%.

PepsiCo Inc. (PEP) posted quarterly earnings and revenue that beat expectations. Shares were up 0.4%.

Chipotle Mexican Grill (CMG) shares rose 2.5% as its first-quarter profit and revenue surged, largely attributed to a 13.4% jump in same-store sales.

Shares of Sabre (SABR), the travel-tech firm which owns the Travelocity website, and Weibo (WB), China's microblog equivalent of Twitter, are expected to attract attention when they debut on the market Thursday. Sabre said late Wednesday its initial public offering had priced at $16 a share, while Weibo priced at $17, the low end of its range, while selling fewer shares than expected.

In other financial markets, European stocks traded mostly lower amid escalating tensions in Ukraine after three pro-Russia activists were killed and 13 wounded in fighting. Asia markets closed mostly higher. Oil prices inched higher, while metals were little changed.

More must-reads from MarketWatch:

Wrong way: Ford, GM return to the bad old days

4 reasons the first quarter was better than it appeared

Why today's market is no stock picker's paradise

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