By Josie Cox 

European stocks tumbled Wednesday, pressured by a fresh bout of downbeat earnings and U.S. economic growth figures dramatically undershooting expectations.

Early afternoon, and having already ended the previous session 1.5% lower on weak corporate earnings, the Stoxx Europe 600 was down 1.1%, mirroring similar declines on Germany's DAX 30, France's CAC 40 and London's FTSE 100.

The S&P 500 was indicated opening 0.5% lower on Wall Street after data showed that the U.S. economy slowed sharply at the start of the year as businesses slashed investment, exports tumbled and consumers showed signs of caution.

"This is a hugely disappointing number and it isn't surprising that we're seeing a real sea of red across equity screens globally," said Philip Lawlor, a partner at London-based Smith & Williamson Investment, which has around GBP15.5 billion of funds under management.

"Equities in Europe are starting to hit the upper band of valuation parameters and investors are starting to look for reasons to take profit, " he said, adding that the weak U.S. data figures are serving that purpose.

Stocks across the whole region have been buoyed by the European Central Bank's asset purchase program, sending many indexes to all-time highs. In recent days though, some investors appear to be turning more cautious on the asset class.

"The argument that European equities look cheap on a relative basis [...] can no longer be made," Michael Barakos, chief investment officer for European equities at J.P. Morgan Asset Management wrote in a recent note.

"We'll need to see earnings growth materialize in order to move sustainably higher," he added.

On Wednesday, however, the earnings season looked mixed at best.

Shares in British American Tobacco PLC, Finnish stainless steelmaker Outokumpu Oyj and Belgian food retailer Delhaize Group were some of the hardest hit by lackluster quarterly figures, while Barclays PLC shares also slipped into the red.

The British bank said it had taken a new GBP800 million ($1.2 billion) charge in the first quarter for potential fines over its foreign-exchange activities, dragging its net profit for the period down to GBP465 million from GBP965 million in the same period last year.

In currency markets on Wednesday, the weak U.S. GDP figures continued to pressure the dollar against the euro, building on the previous day's moves.

The bloc's single currency had already risen to a near three-week high against the dollar on Tuesday, as the greenback was hit by a disappointing U.S. consumer confidence report and the former supported by hopes that Greece might be able to secure some extra funding in the short-term.

On Wednesday, the euro was trading close to 0.7% higher after the U.S. data, at over $1.104.

In debt markets, Government bonds across much of Europe, and especially Germany, sold off sharply, though investors were quick to call the move a blip rather than a sustained reversal in the recent rally.

Yields on German 10-year government debt, which rise as bond prices fall, pushed to 0.25% for the first time in around a month, while yields also rose on government debt in France, Austria and Switzerland, as well as in the Nordics and southern Europe.

Later in the session investors will look to the Federal Open Market Committee's policy statement, released at the conclusion of its two-day meeting, which could shed more light on when the central bank might raise rates. Most market participants, however, don't anticipate major policy changes.

"We don't expect any specific forward guidance on the timing of the liftoff, but September remains our base-case," currency strategists at BNP Paribas wrote in a note.

Write to Josie Cox at josie.cox@wsj.com

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