By Chelsey Dulaney 

Actavis PLC outlined new details of its planned acquisition of Allergan Inc. on Tuesday, including plans to appoint two Allergan directors to its board and a $2.1 billion breakup fee.

Actavis on Monday agreed to pay $66 billion in cash and stock for Allergan in a combination that would make Actavis one of the globe's largest drug makers by sales, led by Allergan's antiwrinkle treatment Botox.

Allergan and Actavis expect a deal, which must be approved by shareholders and regulators, would close in the second quarter next year and be accretive within the first year. The combined company would have $23 billion in sales next year, more than 30,000 employees and a market capitalization of $128 billion, about 12 times Actavis's equity value just two years ago.

In a regulatory filing Tuesday, Actavis set a breakup fee of $2.1 billion if the deal fails to go through. The company's board currently has 14 directors, including Chief Executive Brent Saunders, according to its website.

The deal appears to have shielded Allergan from a hostile takeover by Valeant Pharmaceuticals International Inc., which had teamed up with activist investor William Ackman and his hedge fund Pershing Square Capital to bid $53 billion for Allergan. Valeant CEO Michael Pearson said Monday that the company will review Actavis's offer but indicated the price was now too steep for a counteroffer.

Shares of Allergan, up 88% this year, and Actavis, up 48% this year, were largely inactive premarket.

Write to Chelsey Dulaney at Chelsey.Dulaney@wsj.com

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