Among the companies expected to trade actively in Wednesday's session are FedEx Corp. (FDX), Oracle Corp. (ORCL) and Renren Inc. (RENN).

FedEx said severe winter weather lowered its operating income in the third quarter by about $125 million--resulting in the company missing market estimates--as repeated storms disrupted operations, lowered shipping volume and raised costs. FedEx's report is the first glimpse of just how badly the brutal winter hurt not only the air-express business, but the entire U.S. freight and transportation industry. Shares fell 57 cents to $138 premarket.

Oracle said fiscal third quarter net income rose 2.4% as the corporate-software company continues to show it can fend off online competitors. But Oracle's adjusted profit and revenue growth wasn't as strong as analysts expected. Shares fell 3.1% to $37.64 premarket.

Renren Inc. (RENN) swung to a fourth-quarter profit as the Chinese social-networking company booked a gain tied to a former subsidiary, masking a sharp drop in revenue and higher expenses. The company's revenue outlook for the current quarter missed Wall Street's expectations. Shares fell 9% to $3.43 premarket.

Horizon Pharma Inc. (HZNP) agreed to acquire Vidara Therapeutics Inc. in a cash-and-stock deal valued at about $660 million, as the specialty pharmaceutical company aims to expand its range of products. Shares rose 19% to $17.50.

Pacific Sunwear of California Inc. (PSUN) said its loss widened in the fiscal fourth quarter as the teen-focused specialty retailer reported a decline in net sales during a challenging holiday season. However, the company's outlook for the current quarter surpassed market expectations. Shares rose 9% to $3.27 premarket.

SolarCity Corp. (SCTY) said it swung to a profit in the fourth quarter as revenue nearly doubled. However, the company that installs rooftop solar panels for homeowners and businesses also projected a first-quarter adjusted loss that was wider than expected. Shares fell 64 cents to $76.46 premarket.

 
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Adobe Systems Inc. (ADBE) said its fiscal first-quarter profit slipped 28% as the software company reported higher expenses, masking a slight increase in revenue. But the adjusted bottom-line topped the company's expectation.

General Mills Inc. (GIS) said its fiscal third-quarter sales fell on lower volume, blaming weakness in the overall food industry and bad weather. The cereal maker's net sales missed Wall Street expectations, while earnings met the company's estimates.

Steel Dynamics Inc. (STLD) forecast a surprise drop in first-quarter earnings from last year's level, as the steel producer said severe cold weather led to higher energy costs and lower production and shipments.

Tempur Sealy International Inc. (TPX) said Lawrence Rogers, president and chief executive of Sealy, is retiring from those roles roughly a year after the mattress maker he led was acquired by its larger peer.

Vera Bradley Inc. (VRA) said its fiscal fourth-quarter earnings fell 23% on weaker revenue and as the handbag and accessories designer was hurt by an inventory write-down related to retired patterns and other items. The company also projected fiscal first-quarter and fiscal year earnings that missed expectations.

Write to John Kell at john.kell@wsj.com and Tess Stynes at tess.stynes@wsj.com.

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