Targeted Genetics Reports Second Quarter Financial Results

Date : 07/28/2005 @ 7:30AM
Source : PR Newswire
Stock : Targeted Genetics (MM) (TGEN)
Quote : 0.66  -0.04 (-5.71%) @ 4:42PM
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Targeted Genetics Reports Second Quarter Financial Results

Targeted Genetics Reports Second Quarter Financial Results

SEATTLE, July 28 /PRNewswire-FirstCall/ -- Targeted Genetics Corporation (NASDAQ:TGEN) today announced its financial results for its second quarter ended June 30, 2005. As previously announced, the Company will hold a conference call with analysts at 10:30 a.m. EDT today. The call will be broadcast live over the Internet and can be accessed, along with replay information, at http://www.targetedgenetics.com/.

For the second quarter of 2005, the Company reported a net loss of $5.3 million, or $0.06 per share, compared to $4.5 million, or $0.05 per share for the second quarter of 2004. For the six months ended June 30, 2005, the Company reported a net loss of $10.0 million, or $0.12 per share, compared to $9.3 million, or $0.12 per share for the same period in 2004.

Revenue for the three months ended June 30, 2005 was $1.5 million, compared to $2.8 million for the second quarter of 2004, and was $3.5 million for the six months ended June 30, 2005, compared to $4.1 million for the same period in 2004. Revenue in 2005 and 2004 consisted primarily of development revenue earned under the HIV/AIDS vaccine collaboration with the International AIDS Vaccine Initiative (IAVI) and reflect decreased activity levels as planned compared to 2004.

"We've continued to make good progress during the first half of the year by both advancing our clinical programs and leveraging value from our leadership position in AAV development infrastructure and capabilities through new collaborations. In our inflammatory arthritis program, we met our goal of providing data mid-year, and based on having met the primary endpoints in the study, we are now positioned to move the program forward and begin the next clinical trial in the third quarter," said H. Stewart Parker, president and chief executive officer of Targeted Genetics. "Our HIV/AIDS vaccine program is the initial step in a comprehensive development strategy and we are moving the program forward with the goal of presenting additional clinical trial data at the end of the year. We also continue to make progress in our preclinical programs and are excited about the breakthrough work of our collaborators in congestive heart failure and Huntington's disease."

Operating expenses were $6.6 million for the second quarter of 2005, down from $7.1 million for the second quarter of 2004. This decrease reflects a decrease in general and administrative expense from $2.1 million in 2004 to $1.7 million in 2005, primarily as a result of the sale of the Company's cell therapy subsidiary in July 2004. Operating expenses remained relatively flat at $13.2 million for the six months ended June 30, 2005, compared $13.3 million for the same period in 2004. Year to date operating expenses reflect a decrease in general and administrative expenses and an increase in research and development expenses associated with the Company's arthritis and AIDS vaccine clinical programs, and its preclinical programs in congestive heart failure and Huntington's disease.

Second quarter highlights include:

-- Reported preliminary results of the Phase I clinical trial of tgAAC94 in patients with inflammatory arthritis; demonstrated safety and observed improvements in arthritic signs and symptoms that support continued study of tgAAC94;

-- Highlighted Targeted Genetics' AAV technology assets in eight presentations at the 8th Annual Meeting of the American Society of Gene Therapy;

-- Announced issuance of three additional patents covering Targeted Genetics' AAV vector patent portfolio and approach to increase carrying capacity of AAV vectors, providing expanded potential for future product development and partnering opportunities;

-- Announced breakthrough research by collaborator Dr. Beverly Davidson of the University of Iowa in Huntington's Disease.

About Targeted Genetics

Targeted Genetics Corporation develops molecular medicines for the prevention and treatment of acquired and inherited diseases. The Company has clinical product development programs targeting inflammatory arthritis and AIDS prophylaxis. The Company also has a promising pipeline of preclinical product development programs focused on, congestive heart failure, Huntington's disease, and hyperlipidemia. For more information about Targeted Genetics, visit its website at http://www.targetedgenetics.com/.

Safe Harbor Statement under the Private Securities Litigation Reform Act of 1995:

This release contains forward-looking statements regarding our intellectual property, research programs and clinical trials, our product development and our potential development platforms including AAV vectors and other statements about our plans, objectives, intentions and expectations. In particular, the statements regarding the Company's pipeline and potential application of the research to any future product candidates are forward- looking statements.

These statements, involve current expectations, forecasts of future events and other statements that are not historical facts. Inaccurate assumptions and known and unknown risks and uncertainties can affect the accuracy of forward-looking statements. Factors that could affect our actual results include, but are not limited to, results of animal research are not necessarily indicative of results in humans, the timing, nature and results of our research, potential development of alternative technologies or more effective products by competitors, our ability to obtain and maintain regulatory or institutional approvals, our ability to obtain, maintain and protect our intellectual property and our ability to raise capital when needed, as well as other risk factors described in the section entitled "Factors Affecting Our Operating Results, Our Business and Our Stock Price" in our Quarterly Report on Form 10-Q for the period ended March 31, 2005. You should not rely unduly on these forward-looking statements, which apply only as of the date of this release. We undertake no duty to publicly announce or report revisions to these statements as new information becomes available that may change our expectations.

Investor and Media Contact: Stacie D. Byars Director, Communications Targeted Genetics Corporation 206-521-7392

TARGETED GENETICS CORPORATION (unaudited, in thousands, except per share information)

Quarter ended Year-to-date ended June 30, June 30, Statement of Operations Information: 2005 2004 2005 2004

Revenue under collaborative agreements $1,462 $2,761 $3,462 $4,081

Operating expenses: Research & development 4,808 4,828 9,347 9,065 General & administrative 1,660 2,066 3,545 3,816 Restructure charges 119 221 338 416 Total expenses 6,587 7,115 13,230 13,297 Loss from operations (5,125) (4,354) (9,768) (9,216)

Investment income (loss) (33) 21 67 145 Interest expense (136) (117) (265) (237) Net loss $(5,294) $(4,450) $(9,966) $(9,308)

Net loss per common share $(0.06) $(0.05) $(0.12) $(0.12)

Shares used in computation of net loss per common share 85,628 81,604 85,628 77,239

TARGETED GENETICS CORPORATION (in thousands)

June 30, December 31, Balance Sheet Information: 2005 2004 (unaudited)

Cash and cash equivalents $25,609 $34,096 Other current assets 761 1,057 Property and equipment, net 2,150 2,495 Other assets 31,850 32,317 Total assets $60,370 $69,965

Current liabilities $4,576 $3,995 Long-term obligations and other liabilities 15,992 16,208 Shareholders' equity 39,802 49,762 Total liabilities and shareholders' equity $60,370 $69,965

DATASOURCE: Targeted Genetics Corporation

CONTACT: Stacie D. Byars, Director, Communications of Targeted Genetics

Corporation, +1-206-521-7392

Web site: http://www.targetedgenetics.com/

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