By Don Clark 

Moore's Law helped bring numerous startups into existence, as cheaper chip technology drove developments like personal computers, smartphones and the Internet. But the force that sparked so much innovation lately has thrown cold water on semiconductor startups.

In 2004, venture capitalists helped 62 chip startups get off the ground with seed or first-round funding, according to Dow Jones VentureSource. Since then, investors have become increasingly wary. Just four startups received first-round infusions in 2013 and seven in 2014, with no seed investments in chip companies either year.

The money flowing to semiconductor companies in such early rounds shrank from more than $400 million to $94 million over that time frame.

"No one will take the risk," said Alex Lidow, chief executive of Efficient Power Conversion Corp., who opted to fund his chip startup with his own money and contributions from a manufacturing partner in Taiwan.

The primary reason is cost. Moore's Law, as Intel's co-founder amended it in 1975, states that chip makers will squeeze roughly twice as many transistors on a chip every couple of years. That progress brings many technical benefits, but designing products with more transistors takes more time and money, as does testing them.

International Business Strategies, a Silicon Valley consulting firm, estimated that it costs $132 million to design and test a typical chip at the current state-of-the-art width of chip components, 14 nanometers, or billionths of a meter. At 65 nanometers, a component size introduced about a decade ago, a comparable chip cost $16 million.

Consequently, chip ventures require more startup capital than many types of early-stage company. They are also less likely to pay off quickly or reliably. For instance, a chip made using the latest 14 nanometer process would need to bring $987 million in revenue to meet a return benchmark of 7.5 times the cost of its design, IBS estimates. A 64-nanometer chip would need to take in $123 million to meet the same benchmark.

The story of Tabula Inc. illustrates the enormous pressures on chip startups. The company was founded in 2003 to develop a novel programmable chip. It used Intel's 14-nanometer process and designed a product with more 5 billion transistors.

"The complexity and time and expense associated with doing design at that level was tremendous," said Dennis Segers, who served as Tabula's CEO since 2006. "It proved to be a challenge to us."

The company also faced high expenses to develop software to program its chip, and delays in getting customers to adopt those new development tools, Mr. Segers said. As a result, despite raising more than $200 million, Tabula's investors threw in the towel. The company, which employed 120 people at its peak, recently closed its doors and is selling off its remaining assets.

Big companies are still designing plenty of chips. And some startups founded in the past decade continue to get more money.

Movidius, a company based in Ireland that makes chips used in visual-processing applications, announced on Tuesday a $40 million funding round, one of the biggest for a semiconductor startup in two years.

One investor who has continued to invest in semiconductor startups is Lip-Bu Tan, who is CEO of chip-design software company Cadence Design Systems Inc. as well as chairman of the venture-capital firm Walden International. Some of the recipients are foreign, including India-based Ineda Systems Inc., which makes chips for wearable devices.

"I decided to be a contrarian," Mr. Tan says. "I doubled, tripled down on my bets."

He is the exception, though, and some people worry about the dearth of new entries to the chip sector. The decline in startups means fewer mature companies. Also, in the past, such ventures often were acquired by larger chip companies, helping them develop new products.

"If you look at the semiconductor business, the majority of the innovation has been contributed by startups," said Andy Rappaport, who recently retired from the venture firm August Capital, where he concentrated largely on chip companies.

As venture capitalists shy away from chips, Mr. Rappaport expects some large companies will step up to fill in the gap. Meanwhile, startups that have emerged are devising new strategies to survive. Some are developing products that exploit older production processes.

Others are trying new materials. Mr. Lidow's EPC, for example, is developing chips based on gallium nitride rather the silicon that has been semiconductor industry's mainstay.

But most others will have to adapt to the harsh realities of keeping up with the competition, which means greater spending to stay in the technology race.

"Moore's Law is a discipline for all of us," said Randhir Thaku, executive vice president and general manager of the Silicon Systems group at Applied Materials Inc., the big maker of semiconductor production tools, "to make sure that we behave."

Write to Don Clark at don.clark@wsj.com

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