NEW YORK, July 6, 2015 /PRNewswire/ -- This BCC Research
report provides a comprehensive discussion of NGS technologies,
clinical applications, industry structure, important clinical
sequencing initiatives, global markets, patent status and
companies. Market data covers the years 2014, 2015 and 2020.
Use this report to:
- Identify the main sequencing technologies and learn why genetic
variation is important in clinical testing.
- Examine the global NGS diagnostic markets, characterized and
quantified by disease type, test complexity, test purpose and
geography.
- Focus on the top research initiatives that are contributing to
clinical NGS applications.
- Learn about the main industry acquisitions and strategic
alliances from 2013 through 2015, including key alliance
trends.
Highlights
- The global clinical next-generation sequencing (NGS) market was
valued at $886.1 million in 2014.
This market is expected to grow at a compound annual growth rate
(CAGR) of 31.3%, from $997.1 million
in 2015 to nearly $3.9 billion by
2020.
- NGS-based diagnostic market for reproductive health applications
is expected to increase from $572.9
million in 2015 to $1.7
billion by 2020, at a CAGR of 24.8% from 2015 to 2020.
- The global market for NGS-based cancer applications is expected
to grow at a CAGR of 34.7%, from $206.3
million in 2015 to $915.7
million by 2020.
Introduction & Scope
INTRODUCTION
STUDY GOALS AND OBJECTIVES
BCC Research's goal for this study is to provide an in-depth
analysis of the clinical next-generation sequencing (NGS) industry,
an emerging industry with enormous
market potential. The approach of analyzing the industry is taken
in terms of workflow (e.g., sequencers, sequence capture,
informatics) and key indications where NGS
diagnostics will have market share by 2020. BCC Research examines
the markets for NGS diagnostics for the years 2014, 2015 and 2020.
The global NGS diagnostic markets are characterized and quantified
by disease indication, test complexity, test purpose and geography.
Market segments that provide exceptional growth opportunities
include cancer, rare genetic diseases and reproductive health. The
report provides a comprehensive discussion of NGS technologies,
clinical applications, industry structure, important clinical
sequencing initiatives, global markets, patent status and
companies. The report is designed to aid companies in their
strategic planning efforts for clinical genetic testing.
REASONS FOR DOING THE STUDY
The Human Genome Project (HGP) moved DNA sequencing technology to
the forefront of life science research as a genetic analysis tool.
The HGP relied heavily on Sanger
sequencing by capillary electrophoresis to decipher the DNA
sequence of the bases in the human genome. The HGP led to
significant improvements in the efficiency and costs of DNA
sequencing. During this time period, the sequencing industry
consolidated, resulting in one dominant company, Applied Biosystems
(now Thermo Fisher Scientific).
Beginning in 2005, the launch of next-generation sequencing
technologies radically changed the structure of the industry and
opened up exciting new market applications.
The costs of sequencing have rapidly reduced to the point where it
is now feasible for complex NGS tests to be priced in the range of
other multiplex genetic tests. As a result, opportunities emerged
in clinical applications that are currently reaching fruition. The
NGS clinical market is beginning to establish a foothold in the
molecular diagnostic industry and holds great commercial promise.
More than 85 clinical laboratories are now offering NGS-based
testing services. For many applications, the clinical benefits have
been proven. At the same time, payers and insurance companies are
beginning to provide coverage for these tests, further enhancing
their commercial potential. The outstanding growth potential for
NGS diagnostics makes it particularly timely to update an earlier
report, published in 2013.
CONTRIBUTION OF THE STUDY AND INTENDED AUDIENCE
This report fills a gap in the industry by focusing solely on
clinical applications run on next-generation sequencing
instruments. Because this industry shows great promise,
information about the market will be particularly useful to
companies and other institutions. The report provides a roadmap for
understanding the ways in which next-generation sequencing will be
used in the diagnostic business during the next five years. It is a
useful guide for strategic and business planning, as well as for
learning about the impact new sequencing technologies will have in
clinical diagnostics. This market report will be useful to many
companies involved in the clinical, genetic testing and sequencing
industries. It will be particularly valuable for companies in such
industries as life science research tools, NGS instruments,
molecular diagnostics, informatics clinical laboratories,
pharmaceutical, biotechnology, microfluidics, lab-on-a-chip and
sample preparation.
SCOPE AND FORMAT
The scope of the report includes clinical NGS technologies,
applications, industries, initiatives, patents and companies. The
markets for NGS-based diagnostics are given
for the years 2014, 2015 and 2020. This report reviews the main
sequencing technologies and explains why genetic variation is
important in clinical testing. It then discusses some of the top
research initiatives that are contributing to clinical NGS
applications. Market driving forces are also discussed. The report
examines the markets by test complexity, indication and test
purpose. Test complexity refers to the multiplexing (e.g., the
number of genes covered) and coverage (e.g., the extent to which
the genome is covered) of the test. Examining the market by test
complexity provides valuable insight into which products (e.g.,
sample preparation, NGS instrument, informatics) will be in demand
in the future. The report provides market data and forecasts for
NGS diagnostics by specific applications, including those for
cancer, rare diseases, complex disorders and reproductive
health.
Specific geographic markets are discussed, including North America, Europe, China, Japan
and the rest of the world. Market data covers the years 2014, 2015
and 2020.
Industry sectors analyzed include NGS instruments, target
enrichment, informatics, clinical laboratory testing services,
reproductive health diagnostics, HLA typing, liquid
biopsy, immune sequencing and fusion diagnostics. More than 170
companies in the clinical NGS industry are profiled in this report.
BCC Research provides a summary of the main industry acquisitions
and strategic alliances from 2013 through 2015, including key
alliance trends.
METHODOLOGY
Both primary and secondary research methodologies were used in
preparing this study. BCC Research examined each of the key
end-user market segments that will be
commercially important during the next five years: cancer, rare
genetic disorders, complex disorders and reproductive health. Based
on this analysis, the current and future applications of NGS
technologies are evaluated in each of the major clinical market
segments and sales revenues are forecast for 2015 through 2020.
Based on analysis of both secondary and primary market sources, as
well as the key trends in the industry, the report provides the
current and projected market size for the various clinical NGS
segments for the years 2014, 2015 and 2020.
Read the full report:
http://www.reportlinker.com/p01556799-summary/view-report.html
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