By Angela Chen 

Mylan NV said it will make a formal offer, worth about $33 billion in cash and stock, to buy generic drug maker Perrigo Co., the latest move in a three-way takeover tussle.

Mylan, which had indicated earlier this month that it was considering such a bid, said its offer consists of $60 in cash and 2.2 Mylan shares for each share of Perrigo. Based on Thursday's close, the offer values Perrigo at about $222 a share.

Perrigo shares closed Thursday at $201.63 and were off 1.4% in recent trading.

Mylan shares, meanwhile, have surged this month after the company received its own takeover approach from Teva Pharmaceutical Industries Ltd. worth about $40 billion.

Perrigo has thus far rejected Mylan's advance, and Mylan has spurned Teva.

The three-way fight underscores the deal-making surge that is under way in an industry grappling with slowing growth. At the heart of the frenzy is a quest for new revenue amid pricing pressure from cash-strapped governments and insurers, and increased competition. Indeed, both EpiPen and Copaxone could face generic competition as soon as this year, analysts say.

Mylan and Perrigo generally compete in different segments of the generic-drug business. Mylan is best known for selling generic prescription drugs, though its top-selling product is the EpiPen emergency treatment for allergic reactions. Perrigo makes over-the-counter cough-and-cold remedies and infant formula for chains like Wal-Mart Stores Inc. and Walgreens, which sell the products under their own names.

Write to Angela Chen at angela.chen@dowjones.com

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