By Julie Jargon 

McDonald's Corp. reported first-quarter results that new Chief Executive Steve Easterbrook labeled "disappointing," as U.S sales fell more than expected despite new promotions and other turnaround initiatives in its critical home market.

Sales at U.S. stores open at least 13 months fell 2% in the three months through June, compared with the 1.5% drop analysts polled by Consensus Metrix had expected. Global same-store sales slipped 0.7%, worse than the 0.4% decline Consensus Metrix had forecast.

McDonald's net profit sank 13% in the quarter.

Mr. Easterbrook, who became CEO on March 1, has made a number of changes to try to revive a business that has been losing customers to fast casual outlets and rival fast food chains, including eliminating antibiotics from chicken, introducing better burgers, adding customizable options and emphasizing the freshness of its ingredients. McDonald's also has recently debuted new lemonades, Sirloin burgers and Artisan grilled chicken sandwiches.

But McDonald's said recent products and promotions, such as the sirloin burgers, didn't achieve the expected consumer response.

McDonald's shares slid 0.5% in early afternoon trading, leaving them down about 2% since Mr. Easterbrook took over.

"We believe trends are improving and change is happening faster at McDonald's than it has in the past," RBC Capital Markets analyst David Palmer said in a research note. "That said, this change is driving a gradual improvement rather than a 'big bang' to sales."

Mr. Easterbrook acknowledged that the quarterly results were "disappointing," but said "we are seeing early signs of momentum." He said he expects McDonald's to post positive global same-store sales in the third quarter.

He said McDonald's will continue to work on simplifying its menu and testing all-day breakfast service. McDonald's has been testing all-day breakfast in some markets, the results of which have been encouraging, according to a memo reviewed by The Wall Street Journal, which said franchisees are preparing to roll it out nationwide as soon as October, pending a vote.

Mr. Easterbrook didn't specify a timeframe for a broad rollout of all-day breakfast, but said restaurants will have to simplify their kitchen procedures in order to accommodate it. "If we believe all-day breakfast is a sufficient sales driver, the net net has to be simplification and only on that basis we would be moving forward," he said.

Chief Financial Officer Kevin Ozan said that a wage increase McDonald's approved for workers at its U.S. company-owned restaurants will pressure profit margins in the second half of the year. On July 1, McDonald's began paying workers at its roughly 1,500 company-owned restaurants in the U.S. at least $1 an hour more than the local minimum wage. To help offset higher labor costs, Mr. Ozan said, the company raised menu prices at the end of May, leaving its U.S. prices overall for the second quarter 2% higher than a year earlier.

McDonald's also has been struggling in Asia, where food-safety concerns have scared off many customers. In its division that includes Asia, same-store sales in the quarter fell 4.5%. Europe was the one bright spot, where same-store sales increased 1.2%.

McDonald's reported a profit of $1.2 billion, or $1.26 a share, down from $1.39 billion, or $1.40 a share, a year earlier. Revenue slid 9.5% to $6.5 billion. Analysts polled By Thomson Reuters had forecast $1.23 a share in earnings and $6.45 billion in revenue.

McDonald's has announced some structural moves to improve results, such as selling thousands of restaurants to franchisees and cutting $300 million in costs. Analysts have asked McDonald's if it plans to do something more dramatic, such as spinning off some of its real estate.

During the call, Mr. Ozan said the company is evaluating several financial initiatives to boost shareholder value and that he will update investors at a conference in November. When asked if the company's real estate will be part of the analysis, Mr. Ozan said, "We're looking at everything."

Chelsey Dulaney contributed to this article.

Write to Julie Jargon at julie.jargon@wsj.com

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