By Josie Cox 

European markets slipped Monday as tensions between Russia and the West intensified and the Middle East digested its deadliest day of fighting between Israelis and Palestinians since the most recent conflict began.

The Stoxx Europe 600 closed the session 0.5% lower, with losses extending across all the continent's main bourses. Germany's DAX lagged with a 1.1% slide. In currency markets, the ruble fell against both the euro and U.S. dollar, while Russia's Micex and the dollar-traded RTS Index ended the session down 2.7% and 2.9% respectively, hitting fresh two-month lows.

In the U.S, stocks pulled back too, with the Dow Jones Industrial Average declining 0.5% in late European trade at the beginning of what is one of the busiest weeks of the quarter for corporate earnings reports.

Over the weekend, the U.S. leveled its most explicit allegations yet of Russia's involvement in the downing of a Malaysia Airlines flight last Thursday that left 298 people dead, and subsequent efforts to conceal evidence.

European leaders threatened broad new sanctions against Moscow, departing from their initially muted reaction and marking a turning point in the standoff between the West and the Kremlin.

Also weighing on market sentiment, unrest flared across the Middle East over the weekend. Israel said 13 soldiers were killed and Gaza officials said 96 Palestinians were killed on Sunday.

Initially markets showed a muted reaction to the developments Monday, with strategists at BNP Paribas noting that the tensions between Russia and the West will likely exert greater pressure on President Vladimir Putin to adopt a conciliatory approach, but later the sense of apprehension spread.

Deutsche Bank strategist Jim Reid described the situation as extremely dangerous and delicate. He added that despite the understandable conclusion that the market may be reaching, that diplomacy is the only sensible outcome, the risk of destabilization cannot be discounted.

"This story still has a long way to run," he said.

Alberto Gallo, a strategist at Royal Bank of Scotland Group, warned that investors may be putting too much faith in central banks to rein in tensions and stabilize markets.

"Central banks may manage to overshadow geopolitical tensions for now and the near future," he wrote in a note, but also said that emerging market bonds particularly, could become exposed to significant risks.

On the buy side, Talib Sheikh, a manager of the J.P. Morgan multi-asset income fund, which is part of a multi-asset platform with over $25 billion under management, said that volatility was already edging higher in the wake of this, and that there could be some forced unwinding of risk-on positioning, if it continued to do so.

Typical safe-harbor assets such as gold and U.S. government bonds, having rallied in the direct aftermath of the plane crash, were trading stronger Monday too.

Gold added 0.3% to hit $1,313.70 an ounce while the 10-year U.S. Treasury yield stood at 2.46%, down from around 2.57% before the crash on Thursday. Yields fall as bond prices rise.

UBS economist Paul Donovan said that if tensions in Russia and Gaza escalate further, energy prices would be the first to react. Brent crude, however, was trading little changed on the day, at $107.19 a barrel.

Elsewhere, the corporate earnings season moved into focus Monday.

Shares in Julius Baer Group AG led the pan-European index, closing 8.5% higher, after the Swiss bank said that assets under management rose 8% in the first half of this year and announced plans to take over Israeli lender Bank Leumi's Swiss private banking operation.

In the U.K., shares in Tesco PLC advanced 1.3%, after the U.K.'s biggest retailer said Chief Executive Philip Clarke would leave the company in October to be replaced by Unilever executive Dave Lewis. That news offset the company's latest profit warning.

Finally, Dutch electronics heavyweight Philips NV on Monday reported a 23% fall in net profit due in part to unfavorable exchange rates. It did try to pacify investors, though, stating that earnings should improve in the second half of the year, driven by cost savings and higher sales, particularly at its health care division. Shares in the group closed down 1.1%.

Corrections & Amplifications

Russia's Micex index closed Monday down 2.7%. An earlier version of this article said it closed down 3.6%. (July 21, 2014)

Write to Josie Cox at josie.cox@wsj.com

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