By Jenny Gross

LONDON--Ineos Group Holdings SA said Wednesday it is shutting its petrochemicals plant at Grangemouth, Scotland, and will now decide whether to restart the neighboring refinery.

Ineos, in a statement, said it took the decision after workers voted against its plan to save the business.

"This is a hugely sad day for everyone at Grangemouth," said Calum MacLean, chairman of Grangemouth Petrochemicals. "There was only ever going to be one outcome to this story if nothing changed and we continued to lose money."

It is anticipated that a liquidation process will commence in a week, Ineos said.

Ineos, based in Switzerland, said it will now decide whether to restart the refinery, which the company shut last week ahead of a planned 48-hour strike by union workers. Unite called off the strike, but Ineos said it would keep the site shutdown because of financial distress unless it received a guarantee of no further strikes.

Steam from the Grangemouth site powers the BP PLC (BP)-operated Forties Pipeline System, which carries about 400,000 barrels a day of North Sea output from fields to shore. A prolonged shutdown could block the flow of Forties and squeeze oil supply in the region.

The Ineos site at Grangemouth employs about 1,400 full-time workers.

Write to Jenny Gross at jenny.gross@wsj.com; Twitter: @jgginlondon.

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