NEW YORK, April 10, 2014 /PRNewswire/ --

Today, Analysts Review released its analysts' notes regarding Puma Biotechnology, Inc. (NYSE: PBYI), Alnylam Pharmaceuticals, Inc. (NASDAQ: ALNY), INSYS Therapeutics, Inc. (NASDAQ: INSY), Peregrine Pharmaceuticals Inc. (NASDAQ: PPHM), and VIVUS Inc (NYSE: ESC). Private wealth members receive these notes ahead of publication. To reserve complementary membership, limited openings are available at: http://www.AnalystsReview.com/register

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Puma Biotechnology, Inc. Analyst Notes 

On April 7, 2014, Puma Biotechnology, Inc. (Puma Biotechnology) presented positive results from the Phase II clinical trial of its investigational drug PB272 (neratinib) for the neoadjuvant treatment of breast cancer (I-SPY 2 TRIAL) in an oral presentation at the American Association for Cancer Research (AACR) Annual Meeting 2014 in San Diego, California. According to Puma Biotechnology, the I-SPY 2 TRIAL (Investigation of Serial Studies to Predict Your Therapeutic Response with Imaging And moLecular Analysis 2) is a collaborative effort among academic investigators from approximately 20 major cancer research centers across the country, the U.S. Food and Drug Administration, Quantum Leap Healthcare Collaborative, and the Foundation for the National Institutes of Health (FNIH) Cancer Biomarkers Consortium including major supporters such as The Safeway Foundation and the Bill Bowes Foundation. The full analyst notes on Puma Biotechnology, Inc. are available to download free of charge at:

http://www.AnalystsReview.com/04102014/PBYI/report.pdf

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Alnylam Pharmaceuticals, Inc. Analyst Notes 

On April 7, 2014, Alnylam Pharmaceuticals, Inc. (Alnylam) announced that the European Patent Office (EPO) has upheld the McSwiggen EP 1423406 ('406) patent in oral opposition proceedings in Munich, Germany. According to the release, the McSwiggen patent estate is owned by Alnylam, and was recently obtained through the Company's acquisition of Sirna Therapeutics from Merck. Additionally, the Company stated that the McSwiggen patent family comprises a core component of Alnylam's overall intellectual property (IP) estate for the advancement of RNAi therapeutics as a new class of medicines. Commenting on the news, Laurence Reid, Ph.D., Senior Vice President and Chief Business Officer of Alnylam, stated, "We are pleased with the European Patent Office's decision to uphold the '406 patent from our McSwiggen patent family, a key component of the IP estate we recently obtained through our acquisition of Sirna Therapeutics from Merck. This patent has broad and significant claims describing chemical modifications of RNAi therapeutics, which we believe are critical for the development and commercialization of all RNAi therapeutics. Our IP estate remains a cornerstone in our efforts to advance RNAi therapeutics to patients in need." The full analyst notes on Alnylam Pharmaceuticals, Inc. are available to download free of charge at:

http://www.AnalystsReview.com/04102014/ALNY/report.pdf

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INSYS Therapeutics, Inc. Analyst Notes 

On March 31, 2014, INSYS Therapeutics, Inc. (INSYS) announced that it has completed its previously disclosed three-for-two stock split, effected through a stock dividend. According to the release, the record date for the stock split was the close of business on March 17, 2014, and share distribution occurred on March 28, 2014. Additionally, INSYS said that consequent to the dividend, shareholders received one additional share of the Company common stock, par value $0.0002145, for each two shares they held as of the record date. INSYS President and CEO, Michael L. Babich, stated, "This action increases the liquidity of our stock, and reflects our confidence in the strength and continuing growth of our Company. We are committed to remaining profitable and continuing to build shareholder value with our marketed products and through our robust R&D pipeline." The full analyst notes on INSYS Therapeutics, Inc. are available to download free of charge at:

http://www.AnalystsReview.com/04102014/INSY/report.pdf

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Peregrine Pharmaceuticals Inc. Analyst Notes 

On April 7, 2014, Peregrine Pharmaceuticals Inc.'s (Peregrine Pharmaceuticals) stock went up by 2.72% to $1.89 per share. For the past three-month trading period, the Company's stock went up by 19.62%, compared to the Nasdaq Composite which went down by 1.77%. The full analyst notes on Peregrine Pharmaceuticals Inc. are available to download free of charge at:

http://www.AnalystsReview.com/04102014/PPHM/report.pdf

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VIVUS Inc. Analyst Notes 

On April 7, 2014, VIVUS Inc.'s (VIVUS) stock went down 6.09%, at $5.09 per share. Over the past five-day trading period, VIVUS shares went down by 11.00%, compared to the Nasdaq Composite which went down by 2.83% over the same trading session. The full analyst notes on VIVUS Inc. are available to download free of charge at:

http://www.AnalystsReview.com/04102014/ESC/report.pdf

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