RNS Number : 9520U
Acambis PLC
21 May 2008
Directors' interests in shares - purchase of shares
Cambridge, UK and Cambridge, Massachusetts - 21 May 2008 - Acambis plc ('Acambis') (LSE:
ACM) announces that on 21 May 2008 share
purchases under the Company's recently completed Placing and Open offer were made by all
eligible Directors:
Peter Fellner, Chairman
Ian Garland, Chief Executive Officer
Elizabeth Jones, Chief Financial Officer
Dr Michael Watson, Executive Vice President, Research and Development
Ross Graham, Chairman of Audit Committee
Director Number of shares Price paid per share Total number of Percentage
of
purchased shares following issued
share
purchase capital
held
Peter Fellner 10,500 115p 40,500 0.028%
Ian Garland 7,000 115p 27,000 0.019%
Elizabeth Jones 3,530 115p 13,616 0.009%
Michael Watson 3,500 115p 13,500 0.009%
Ross Graham 7,247 115p 27,955 0.019%
Enquiries
Acambis plc +44 (0) 1223 275 300
Ian Garland / Elizabeth Jones / Lyndsay Wright
Brunswick +44 (0) 20 7404 5959
Jon Coles / Justine McIlroy / Annabel Entress
About Acambis
Acambis is a leading vaccine company developing novel vaccines that address significant
unmet medical needs or substantially improve
standards of care. ChimeriVax*-JE, Acambis' most advanced product in its development-stage
pipeline, has to date shown an excellent safety
and efficacy profile following pivotal Phase 3 trials. It is currently undergoing paediatric
trials in the endemic region and is partnered
with sanofi pasteur. Acambis' proprietary ChimeriVax* technology, developed in association
with St Louis University, has also been used to
develop ChimeriVax*-West Nile, which is undergoing Phase 2 clinical testing, making it the
most advanced investigational vaccine against the
West Nile virus. Acambis has established a global collaboration with sanofi pasteur for
further development and commercialisation of the
vaccine. ChimeriVax* has also been applied to development of sanofi pasteur's tetravalent
dengue vaccine, which has successfully
demonstrated proof-of-concept in a Phase 2 trial by generating 100% seroconversion to all four
dengue virus serotypes.
Acambis' ACAM-CDIFF* is the only vaccine in development against Clostridium difficile
bacteria, a leading cause of hospital-acquired
infections. C. difficile is estimated to cause at least 360,000 cases of C.difficile-associated disease in the US alone, and annual costs
to US and European healthcare systems are estimated to be in excess of $7bn a year. Acambis'
influenza programme aims to develop a universal
vaccine against influenza, for which a universal 'A' strain vaccine, ACAM-FLU-A*, was recently
tested in a Phase 1 trial and pre-clinical
challenge study. Acambis is currently undertaking pre-clinical testing of a vaccine candidate,
dl5-29, against genital herpes.
Acambis is recognised internationally as the leading producer of smallpox vaccines for
emergency-use stockpiles held by the US
Government and several other governments around the world. Acambis developed its ACAM2000*
smallpox vaccine under contracts with the US
Government.
Acambis is based in Cambridge, UK and Cambridge, Massachusetts, US, and is listed on the
London Stock Exchange (ACM). More information
is available at www.acambis.com.
"Safe Harbour" statement
Statements contained within this news release may contain forward-looking comments, which
involve risks and uncertainties that may cause
actual results to vary from those contained in the forward-looking statements. In some cases,
you can identify such forward-looking
statements by terminology such as 'may', 'will', 'could', 'forecasts', 'expects', 'plans',
'anticipates', 'believes', 'estimates',
'predicts', 'potential', or 'continue'. Predictions and forward-looking references in this
news release are subject to the satisfactory
progress of research which is, by its very nature, unpredictable. Forward projections reflect
management's best estimates based on
information available at the time of issue.
This information is provided by RNS
The company news service from the London Stock Exchange
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