By Tess Stynes 

Bristol-Myers Squibb Co. reported stronger-than-expected fourth-quarter revenue, boosted by strong sales of its key drugs and despite a hit from the divestiture of its diabetes business last year and impacts from a stronger dollar.

The drug maker is poised for a management shift as the leaders who transformed the drug maker into a leader in immunotherapies exit. Most recently, Bristol Chief Operating Officer Giovanni Caforio was been tapped as its new chief executive, effective in May. The successor to current CEO Lamberto Andreotti faces the task of maintaining Bristol's early lead in immunotherapy drugs. Mr. Andreotti, who plans to retire as CEO later this year, was among the Bristol executives that conceived and executed its makeover.

Bristol pioneered the move into immunotherapies--drugs that work by unleashing the body's immune system to fight cancer--starting with its $2.4 billion purchase of Medarex and then its winning approval, in 2011, of skin-cancer immunotherapy Yervoy. Late last year, Bristol received approval for a second immunotherapy, Opdivo, also for skin cancer. Opdivo recently has shown positive results in studies in treating other cancers.

In the latest quarter, Yervoy sales surged 41% to $366 million, while Opdivo contributed sales of $5 million.

Overall, Bristol reported a profit of $13 million, or a penny a share, down from $726 million, or 44 cents a share, a year earlier. Excluding a pension-related charge and other items, per-share earnings fell to 46 cents from 51 cents.

Revenue decreased 4.1% to $4.26 billion. However, excluding impacts of the divested diabetes business, global revenue rose 6%, or 9% excluding currency fluctuations.

Analysts polled by Thomson Reuters expected per-share profit of 41 cents and revenue of $4.03 billion.

In its hepatitis C segment, Daklinza and Sunvepra posted combined sales of $207 million.

Sales of leukemia drug Sprycel increased 9% to $398 million. Sales of blood-thinner Eliquis--sold by Bristol and collaboration partner Pfizer Inc.--soared to $281 million from $71 million. The drug, previously approved for uses such as stroke prevention in atrial fibrillation, received regulatory approvals in August to treat recurring deep vein thrombosis and pulmonary embolism.

Last week, Johnson & Johnson reported fourth-quarter sales slipped 0.6% despite surging prescription-drug sales, in a sign of what the stronger dollar may mean for U.S. companies counting on overseas markets.

For the year, Bristol forecast per-share earnings of $1.55 to $1.70 and revenue between $14.4 billion and $15 billion, assuming current currency rates. Analysts polled by Thomson Reuters expected per-share profit of $1.71 and revenue of $15.61 billion.

Write to Tess Stynes at tess.stynes@wsj.com

Access Investor Kit for Bristol-Myers Squibb Co.

Visit http://www.companyspotlight.com/partner?cp_code=P479&isin=US1101221083

Subscribe to WSJ: http://online.wsj.com?mod=djnwires

Bristol Myers Squibb (NYSE:BMY)
Historical Stock Chart
From Mar 2024 to Apr 2024 Click Here for more Bristol Myers Squibb Charts.
Bristol Myers Squibb (NYSE:BMY)
Historical Stock Chart
From Apr 2023 to Apr 2024 Click Here for more Bristol Myers Squibb Charts.