By Ilan Brat 

It used to be easy for people like Kristen D'Amico, who can't stand the taste of pumpkin pie. She merely had to say no to a slice of it on Thanksgiving Day.

Not anymore.

A rising tide of products flavored with pumpkin pie spice has flooded grocery store shelves and restaurant menus, and not just near her home in Deltona, Fla. Friends tease the 34-year-old stay-at-home mother with gleeful photos and text messages about pumpkin lattes, coffee creamers and pies. Relatives mock her, she says, at Thanksgiving dinner for shunning pumpkin in all its forms.

The pumpkin craze "really is an epidemic," she says, adding that she must have missed the indoctrination session where people "were brainwashed, and I'm like, 'What's wrong with these people?' "

Pumpkin pie spice--a blend of sugar, ground cinnamon, nutmeg and allspice--evokes the taste and smell of pumpkin pie. And it is being used in everything from English muffins to dog food, beer and cornbread. "Smells like heaven, right?" says Meghan McAndrews of General Mills, promoting the Betty Crocker recipe.

The ragged band of people immune to the charms of pumpkin pie spice feel increasingly misunderstood and shunned despite their best efforts to thwart its highly commercialized advance. Haters have organized anti-pumpkin days and railed against the ubiquitous flavor in raps and online diatribes. Still, the onslaught continues with pumpkin-spice hummus and Country Crock Pumpkin Spice spread. Beeradvocate.com lists 100 top-rated pumpkin beers. There is a pumpkin spice shade of nail polish and a pumpkin spice whey-protein flavor.

It's all too much for Jesse McDonald, a 35-year-old indie rapper, who remembers in his childhood in Halifax, Nova Scotia, touching the slimy, stringy guts of a pumpkin while carving his first jack-o'-lantern. Ever since, he has had an aversion to the feel, smell and taste of pumpkin.

Two years ago, Mr. McDonald, whose stage name is Jesse Dangerously, returned home from a U.S. tour and put out a song titled "Pumpkin Spice Swag," envisioning a pumpkin-spice Armageddon, where the world is overrun with pumpkin-spice police and pumpkin-spice iPhones.

But fans mistook his complaints for an ode. One baked him a pumpkin-spice birthday cake and another sent him a pumpkin-spice-scented hat, which he says took six months to air out.

Ms. D'Amico, who with a friend runs a YouTube channel called PlanetMommyhood, has tired of the horrified looks she provokes by mentioning how much she hates pumpkin and pumpkin pie spice.

She recently posted on the site's Facebook page something about pumpkin spice engulfing her food and beverage options--and got harsh reactions from dozens of friends and followers.

"I didn't say that your baby is ugly. I said that pumpkin spice is gross. Calm down!" she says. "I'm praying; this is a nightly prayer, that it goes away."

Len Gigante, a retired hostage negotiator, tried to launch a National Anti-Pumpkin Day three years ago, but says he got nowhere. He thinks it might be a losing battle.

Some blame Starbucks Corp. for turning the seasonal pumpkin-spice trend into a mass-market mammoth with the 2003 introduction of its pumpkin-spice latte. Pumpkin-flavored offerings in 2013 drew retail sales of nearly $350 million, up 14% from the previous year, according to Nielsen, the market-research firm. Pumpkin growers, meanwhile, have seen increased demand boost the average price of whole pumpkins by 33% to $13.30 per hundred pounds since 2006, according to the U.S. Department of Agriculture.

When Nashville author Jon Acuff recently spotted a bag of pumpkin-pie spice flavored pumpkin seeds, he said he knew the trend had gone too far. Its sickening pervasiveness threatens to spoil his pumpkin-inspired fondness for the cheerful autumn days of his childhood in Massachusetts, he says. "We're flying too close to the sun on wings made of pumpkin spice."

But there is no unanimity about pumpkin pie. For one thing, pumpkins are a squash. And some recipes suggest making "pumpkin pie" with butternut squash. A pumpkin soup tastes nothing like a pumpkin pie. Pumpkin pie spice is a smell as well as a taste. The smell and taste bother people, and some people just don't like pumpkin itself. John Oliver, on his HBO show "Last Week Tonight" unleashed a three-minute attack on the flavor. He said, "I, personally, for instance, would rather drink a cable-knit-sweater-spice latte."

In early November, after a cold front moved into the Northeast, Katie Pyle stopped into a Starbucks in Hoboken, N.J., for her first pumpkin-spice latte of the year. Then she dashed off a message to her Facebook followers, condemning "the haters. I just had my first pumpkin spice latte of the season and it was FRICKIN' DELICIOUS."

The post became one of her most popular ever among her small group of followers, generating 45 likes and several laudatory comments.

"It's a cold-winter drink, and I feel like it's something that I use to get myself through the miserable, cold weather," she says.

Nielsen Senior Vice President of Consumer Insights Andrea Riberi says pumpkin could soon have competition as the number of cranberry-flavored products multiply. And that leaves a sour taste in many mouths, too.

But Americans' emotional ties to pumpkins will linger, says Cindy Ott, a professor at Saint Louis University who in 2012 published the book, "Pumpkin: The Curious History of an American Icon."

Pumpkins, treasured for their abundant production by the American colonists and later used as a last-resort animal feed by farmers in the late 1800s, rekindle Americans' reverence for the small family farm, she says.

"The pumpkin's been around a long time, so it's not like it's going to go anywhere," she says.

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