By Rex Crum, MarketWatch

SAN FRANCISCO (MarketWatch) -- IBM Corp. stood out among a slate of tech losses Thursday as investors turned against the computer-services giant following a disappointing quarterly earnings report.

IBM (IBM) was off by $7.53 a share, or almost 4%, at $188.98 after the company said late Wednesday that it earned $2.38 billion, or $2.29 a share, for its first quarter ended in March. During the same period a year ago, IBM earned $3.03 billion, or $2.70 a share. Revenue declined by 4% to $22.5 billion.

Excluding one-time items, IBM would have earned $2.54 a share, which was in line with estimates of analysts surveyed by Thomson Reuters, who had also forecast IBM to report $22.91 billion in revenue.

The results showed IBM's lowest quarterly revenue since it reported $21.71 billion in the first quarter of 2009. The main source of IBM's sales drop was the company's hardware sales, which declined 23% from a year ago to $2.4 billion. The company has been moving more into software and cloud-based services and is in the middle of selling its low-end server business to Lenovo Group.

Still, such moves have yet to spur meaningful sales or earnings improvements at IBM. Analyst Brian Marshall, of ISI Group, said the company "has a long history of proactively discarding unattractive businesses" such as hard-disk drives, printers and PCs, but that Chief Executive Virginia Rometty and Chief Financial Officer Martin Schroeter need to take more dramatic action in order to transform the company.

"Unfortunately, the pace of change in tech has only accelerated and we believe the focus now needs to turn to building attractive new multi-billion dollar business lines rather than shedding old ones," Marshall said.

In spite of IBM's losses, much of the tech sector rallied, with SanDisk Corp. (SNDK) among the top gainers. The memory and storage-chipmaker's shares rose 10% to $83.65 after SanDisk reported upbeat quarterly sales and earnings late Wednesday.

Twitter Inc. (TWTR) was up by 4% at $46.19 after the company said MoPub, its new mobile-advertising product, will be able to reach more than 1 billion devices and rival Facebook Inc.'s (FB) user base.

Gains also came from Apple Inc. (AAPL), Netflix Inc. (NFLX), Micron Technology Inc. (MU) and Amazon.com Inc. (AMZN).

The Nasdaq Composite Index (RIXF) reversed course from its early losses and rose 15 points to 4,101. The Philadelphia Semiconductor Index (SOX) was also up by 1.5%.

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