ADVFN - Advanced Financial Network.
HOME» NASDAQ » M » MDVN Stock Price » MDVN Stock News

Medivation Share News

 Medivation (mm) Stock Price
MDVN Stock Price
 Medivation (mm) Stock Chart
MDVN Stock Chart
 Medivation (mm) Stock News
MDVN Stock News
 Medivation (mm) Company Information
MDVN Company Information
 Medivation (mm) Stock Trades
MDVN Stock Trades

Baxter Bumps Up Schedule For 2nd Late-Stage Alzheimer's Study

By Jon Kamp Of DOW JONES NEWSWIRES Baxter International Inc. (BAX) is pushing up the start time for a second, late-stage study designed to test the company's Gammagard drug as a potential Alzheimer's disease treatment based on positive data in a smaller-scale study. The opportunity to tap the large and potentially lucrative Alzheimer's market remains years away for the Deerfield, Ill., company, which declined to issue a timeline for the new study. But moving up the launch plan is a positive sign for the program, analysts said. The smaller-scale study of 24 Alzheimer's patients showed cognitive and functional benefits for those on Gammagard at 18 months compared with patients who initially received a placebo, Baxter announced late Tuesday. Imaging scans also showed benefits for Gammagard patients on measures of brain atrophy and enlargement in the brain. These data require validation in larger-scale research before Baxter can open up a big, new market, and that entails some risk. Medivation Inc. (MDVN) reported last month that an experimental Alzheimer's treatment in development with Pfizer Inc. (PFE) failed to show effectiveness in a large late-stage study, for example, marking a major setback. Baxter already has one late-stage study for Gammagard underway, which could produce preliminary results by the second half of 2012. The company previously planned to start the other late-stage study after the first one, which includes 360 patients, but now plans to run them concurrently. This is being done based on the strength of the smaller study's data, said Hartmut Ehrlich, vice president of research and development in Baxter's BioScience business, in a release. A Baxter spokesman confirmed Wednesday that the second late-stage study's timeline has been bumped up but said it's too early to say what the timeline might look like. The company needs to discuss the study design with the Food and Drug Administration. Morgan Stanley analyst David Lewis called Tuesday's data "far from definitive" but said "the decision to run the second Phase III trial concurrently with the first is an important and perhaps positive signal from Baxter." Alzheimer's is a progressive, brain-damaging disease that is expected to grow in prevalence as baby boomers age. Because there are limited treatment options today, it remains a sought-after market for drug makers. Baxter is chasing that prize with Gammagard, an existing, decades-old drug made from donated human plasma. It is one of many intravenous immunoglobulin, or IVIG, drugs, and it is commonly used to treat malfunctioning immune systems. The aim of using the drug against Alzheimer's is, essentially, to replenish what may be a depleted reservoir of natural antibodies that can remove an Alzheimer's-linked substance called beta-amyloid from the brain. UBS analyst Bruce Nudell said he remains "cautiously optimistic" on the Alzheimer's opportunity for Baxter. William Blair's Ben Andrew estimated Baxter won't receive FDA approval or broad reimbursement coverage before about 2015, suggesting that opportunity is still a distant one. Baxter shares recently traded 0.5% lower to $58.76. -By Jon Kamp, Dow Jones Newswires; 617-654-6728; jon.kamp@dowjones.com

Stock News for Medivation (MDVN)
DateTimeHeadline
04/29/201606:00:00Sanofi CEO Seeks Talks With Medivation Over $9.3 Billion Offer
04/29/201603:03:00Abbott to Acquire St. Jude -- WSJ
04/29/201603:03:00Cancer Drugs Entice Big Buyers -- WSJ
04/29/201603:00:00Sanofi CEO Seeks Talks With Medivation Over $9.3 Billion Offer...
04/28/201618:10:00Drugmakers Place Big Bets on Cancer Medicines
04/28/201617:42:00Abbott Agreed to Buy St. Jude in $25 Billion Deal--6th Update
04/28/201617:15:00Drugmakers Place Big Bets on Cancer Medicines
04/28/201617:02:24Additional Proxy Soliciting Materials (definitive) (defa14a)
04/28/201616:57:34Proxy Statement (definitive) (def 14a)
04/28/201616:17:53Current Report Filing (8-k)
04/28/201606:52:00Sanofi Makes Offer for Medivation in $9.3 Billion Deal -- 2nd...
04/28/201606:34:27Additional Proxy Soliciting Materials - Non-management (definitive...
04/28/201604:11:00Sanofi Makes Offer for Medivation in $9.3 Billion Deal -- Update
04/28/201603:20:00Sanofi Makes $9.3 Billion Bid for Medivation
04/28/201603:00:00Sanofi Makes Offer for Medivation in $9.3 Billion Deal
04/12/201617:43:00Medivation Has Rejected Buyout Approach From Sanofi -Bloomberg
04/08/201617:07:39Statement of Changes in Beneficial Ownership (4)
04/08/201617:06:45Statement of Changes in Beneficial Ownership (4)
04/08/201617:05:50Initial Statement of Beneficial Ownership (3)
04/08/201617:02:17Amended Current Report Filing (8-k/a)

Medivation and other NASDAQ stock quotes are delayed by at least 20 minutes.
All other stock price and quote data is delayed by at least 15 minutes unless otherwise stated. By accessing the services available at ADVFN you are agreeing to be bound by ADVFN's Terms & Conditions
Contact Us | Copyright 1999-2015 ADVFN PLC. | Privacy Policy | Investment Warning | Data accreditations | Investor Relations

ADVFNADVFN ItalyADVFN GermanyADVFN FranceADVFN BrazilADVFN JapanADVFN UKADVFN US noad